A5016382948- Wound Healing and Treatments
- Trauma Management and Diagnosis
- Virus-based gene therapy research
- Mesenchymal stem cell research
- Bone Tissue Engineering Materials
- Cancer Research and Treatments
- Pluripotent Stem Cells Research
- Pleural and Pulmonary Diseases
- Uterine Myomas and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Case Reports on Hematomas
- Diabetic Foot Ulcer Assessment and Management
- Monoclonal and Polyclonal Antibodies Research
- Graphene and Nanomaterials Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Cardiac Arrest and Resuscitation
- Additive Manufacturing and 3D Printing Technologies
- Streptococcal Infections and Treatments
- RNA Interference and Gene Delivery
- 3D Printing in Biomedical Research
- Planarian Biology and Electrostimulation
- Pneumothorax, Barotrauma, Emphysema
- Periodontal Regeneration and Treatments
Grady Memorial Hospital
2023
Jackson Health System
2021
University of Miami
2021
University of Chicago
2017-2020
University of Chicago Medical Center
2017-2019
Molecular Oncology (United States)
2017-2019
With rapid advances in understanding molecular pathogenesis of human diseases the era genome sciences and systems biology, it is anticipated that increasing numbers therapeutic genes or targets will become available for targeted therapies. Despite numerous setbacks, efficacious gene and/or cell-based therapies still hold great promise to revolutionize clinical management diseases. It wildly recognized poor delivery limiting factor most vivo There has been a long-lasting interest using viral...
Advances in three-dimensional (3D) printing have increased feasibility towards the synthesis of living tissues. Known as 3D bioprinting, this technology involves precise layering cells, biologic scaffolds, and growth factors with goal creating bioidentical tissue for a variety uses. Early successes demonstrated distinct advantages over conventional engineering strategies. Not surprisingly, there are current challenges to address before bioprinting becomes clinically relevant. Here we provide...
Effective bone tissue engineering is important to overcome the unmet clinical challenges as more than 1.6 million grafts are done annually in United States. Successful needs minimally three critical constituents: osteoprogenitor cells, osteogenic factors, and osteoinductive/osteoconductive scaffolds. Osteogenic progenitors derived from multipotent mesenchymal stem cells (MSCs), which can be prepared numerous sources, including adipose tissue. We previously showed that BMP9 most BMP induces...
Due to availability and ease of harvest, adipose tissue is a favorable source progenitor cells in regenerative medicine, but has yet be optimized for osteogenic differentiation. The purpose this study was test cranial bone healing surgical defect model utilizing morphogenetic protein-9 (BMP-9) transduced immortalized murine adipocyte (iMAD) citrate-based, phase-changing, poly(polyethylene glycol citrate-co-N-isopropylacrylamide) (PPCN)-gelatin scaffold. Mesenchymal iMAD were with adenovirus...
Pocivavsek, Luka MD, PhD; Bishop, Elliot MD; Khabaz, Kameel; Ota, Takeyoshi Skelly, Christopher FACS; Hampton, David MEngAuthor Information
Objective There is a need for cancer imaging in the clinic and operating room. We have shown that fluorescently labeled antibodies can detect microscopic islands of head neck cells using modified intraoperative microscopes preclinical animal studies. Here we evaluated optimal targeting molecule clinical translation. Method assessed vitro binding EGFR (cetuximab/Erbitux panitumumab/Vectibix) an antibody mimetic (anti‐EGFR affibody) multiple cell lines (SCC5, OSC19, FADU). To compare vivo...