A5019309870- Glaucoma and retinal disorders
- Neurological Disorders and Treatments
- Ophthalmology and Eye Disorders
- Ocular Infections and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Ocular Disorders and Treatments
- Retinal and Optic Conditions
- Ocular and Laser Science Research
- Ocular Surface and Contact Lens
- Retinal Development and Disorders
- Acne and Rosacea Treatments and Effects
- Cerebral Venous Sinus Thrombosis
- Thermography and Photoacoustic Techniques
- Forensic and Genetic Research
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Biomedical Research and Pathophysiology
- Infrared Thermography in Medicine
- Terahertz technology and applications
- Magnesium in Health and Disease
- Spectroscopy Techniques in Biomedical and Chemical Research
- Nanoplatforms for cancer theranostics
- Advanced Glycation End Products research
- Corneal surgery and disorders
- Corneal Surgery and Treatments
Federal State Scientific Institution Research Institute of Eye Diseases
2020-2024
Helmholtz Moscow Research Institute of Eye Diseases
2018-2022
Abstract One of the approaches to restoring structure damaged cartilage tissue is an intra‐articular injection tissue‐engineered medical products (TEMPs) consisting biocompatible matrices loaded with cells. The most interesting are absorbable from decellularized tissues, provided that cellular material completely removed them maximum possible preservation and composition natural extracellular matrix. present study investigated mechanical, biochemical, biological properties porcine...
In this paper, terahertz (THz) pulsed spectroscopy and solid immersion microscopy were applied to study interactions between water vapor tissue scaffolds–the decellularized bovine pericardium (DBP) collagen matrices, in intact form, cross-linked with the glutaraldehyde or treated by plasma. The water-absorbing properties of biomaterials are prognostic for future cell-mediated reactions recipient scaffold. Complex dielectric permittivity DBPs was measured 0.4–2.0 THz frequency range, while...
Purpose — to study the effect of a mid-infrared laser with wavelength 3.0 μm on eye tissue. Materials and methods . An experimental device “Laser scalpel in middle infrared range 2–8 for precision surgery” was used. The radiation spectrum generated by this coincides spectral absorption peaks such biological tissue chromophores as water, proteins cholesterol esters, which makes it possible use surgery (ophthalmology, neurosurgery, vascular surgery). In study, we chose 3 µm, peak water....
To analyze the chemical composition of sclera and trabecular meshwork in patients with primary open-angle glaucoma (POAG) to assess impact corneal-compensated intraocular pressure (IOP) on chemistry drainage area.Biopsy specimens (89 specimens) (41 obtained from POAG maximal medical therapy were analyzed determine content certain elements - carbon (C), nitrogen (N), oxygen (O), aluminum (Al), calcium (Ca), chlorine (Cl), potassium (K), magnesium (Mg), sodium (Na), phosphorus (P), silicon...
Glaucoma therapy is directed towards intraocular pressure stabilization. Pathological diurnal fluctuations of (IOP), as well its average value during 24 hours, a significant risk factor or primary open-angle glaucoma (POAG) progression. Currently, whole range pharmacological drugs used for IOP correction. They differ in hypotensive effect degree, which, turn, can depend on the time administration. Tafluprost, prostaglandin analogue, has hypotensive and effectively decrease amplitude...
Standard bacteriological examinations, which involve culturing microorganisms at 37 °C, are commonly used in clinical practice for diagnosing infectious diseases. However, the growth temperature of on ocular surface (OS) during keratitis (IK) may not coincide with laboratory standard, is due to characteristic features heat exchange eye.
A comprehensive understanding of intercellular and cell–matrix interactions is essential for advancing our knowledge cell biology. Existing techniques, such as fluorescence microscopy electron microscopy, face limitations in resolution sample preparation. Supravital lanthanoid staining provides new opportunities detailed visualization cellular metabolism interactions. This study aims to describe the structure, elemental chemical, probable origin zones extreme (neodymium) accumulation that...
This study provides a detailed analysis of the bioinorganic chemical composition lens substance in patients with senile cataract using classical and spatial statistics methods.The included 30 isolated human lenses. The light scattering ability (LSA) was evaluated an original method. Additionally, distribution elements analyzed scanning electron microscope energy dispersive spectrometer (SEM/EDS). Measurements by all methods were carried out single coordinate space, which made it possible to...
Relevance. In modern ophthalmology, for the diagnosis of inflammatory diseases ocular surface, a new technique is needed that allows significantly reducing study time, increasing informative value visual data. Scanning electron microscopy can become such method, provided determinant atlas created with set reference cultures preliminary identification microorganisms detected on surface. Purpose. The purpose our to create an microorganisms, samples which were prepared by method lanthanide...
To determine the possibilities of impression cytology (IC) with subsequent visualization sample on a scanning electron microscope in assessment normal microflora ocular surface.
To study the effectiveness of monotherapy with bimatoprost in patients decompensated intraocular pressure (IOP).90 (132 eyes) stage I-II glaucoma and IOP previously treated timolol, latanoprost travoprost were included study. Average at beginning was 25.4±2.5 mmHg. All had their hypotensive medications substituted by bimatoprost. The examined during initial appointment, as well after 4 12 weeks.IOP decrease highest group who been timolol: initially 26.2±1.8 mmHg, weeks - 21.0±2.2 20.8±1.9...
PURPOSE: There are two primary aims of this study: 1. To perform a comparative chemical analysis aqueous humour (AH), scleral tissue, and trabecular meshwork in patients with open-angle glaucoma (POAG). 2. evaluate the tissue’s composition at different POAG stages pseudoexfoliation (PEG). METHODS: The concentration certain elements — carbon (C), nitrogen (N), oxygen (O), aluminum (Al), calcium (Ca), chlorine (Cl), potassium (K), magnesium (Mg), sodium (Na), phosphorus (P), silicon (Si),...
Продолжается внедрение новых методов химического анализа в фундаментальные медико-биологические исследования. Возникают дополнительные данные о содержании малых элементов тканях, роль которых химических реакциях организма может рассматриваться по аналогии с поведением уже изученных. Существующее многообразие классификаций не полной степени отражает их группировку сходной роли метаболизме, основанной на химическом родстве. В статье рассмотрены актуальные классификации биологических систем и...
Was to assess the possibility of using chemical analysis bone mineral content by means an energy dispersive X-Ray spectroscopy determine age unidentified corpses for forensic identification. A semi-quantative microanalysis fragments 85 male and female aged between 21 91 was done through use spectrometer. The association tissue apatite composition with is confirmed a formula, connecting change, proposed. quantitive evaluation elements in normative corpse's standard laboratory, equipped...
Infectious keratitis poses a significant diagnostic challenge due to the diverse range of causative agents involved, including difficult-to-cultivate and atypical pathogens that are often missed by standard identification methods. Purpose. This study aims present clinical cases where successful preliminary verification in infectious was achieved using scanning electron microscopy (SEM) lantanoid staining. Material The article describes two patients with special status ocular surface,...