Background: Tuberculosis (TB) and chronic pain are global health concerns that affect millions of people, often requiring long-term, effective treatment strategies. The conventional therapies used to manage these conditions come with significant limitations. In TB, long durations, poor compliance, drug resistance, toxicity first-line drugs key challenges. Similarly, management faces issues, such as inadequate targeting, systemic side effects, tolerance analgesics, limiting traditional...

Objectives: The objective of the current studies to enhance formulation DS-loaded liposomes through utilization Response surface methodology (RSM) and involving computation approach for their validation.
 Methods: optimization was conducted using RSM, focusing 2 main key parameters including encapsulation efficiency (% EE) In-vitro drug release DR) 12 hours via QbD. To formulate an optimize liposome utilizing a 32 factorial design, with phospholipid cholesterol (CH) concentrations being...

Objectives: The ongoing research aims to enhance the development of LNH-loaded nanogel by utilizing DoE as computational method statistically validate their formulation.
 Methodology: In this Chitosan used a natural polymer and Poly (Ethylene glycol) [PEG] penetration or permeation enhancer. different LNH were synthesized using Nanoprecipitation Dispersion method, with variations in drug-polymer ratio (1/0.03, 1/0.08, 1/0.12). process parameters carefully optimizing for efficiency...

Introduction: In India, the regulatory body for catechu is Food Safety and Standards Authority of India (FSSAI). The FSSAI responsible regulating manufacture, sale, distribution food in including catechu. has set standards purity quality catechu, it also monitors market adulterated FDA (The Drug Administration) safety efficacy drugs dietary supplements United States (US). not approved as a drug or supplement, but does regulate additive. limits on amount that can be added to Objective:...

Prachi Pandey, Rahul Pal, Vinay Kumar Rao Khadam, Himmat Singh Chawra and Ravindra Pal Author informationCitations Corresponding author. Correspondence: Ms. Pandey Department of Pharmaceutics, Nims Institute Pharmacy, University Rajasthan, Jaipur-303121, INDIA. Email: pandeyprachi167@gmail.com Notes February 06, 2024; April 09, 30, 2024. Copyright License information ©2024

The field of pharmaceutical science and drug delivery has seen a remarkable transformation in recent years, marked by the emergence diverse advanced approaches development Novel Drug Delivery Systems (NDDs) their associated carriers.Nanocarriers are tiny particles that can be used to deliver drugs body.They typically less than 100 nanometres diameter, which is about 1,000 times smaller width human hair.NDDs play pivotal role enhancing therapeutic efficacy, safety, patient compliance...

The formulation development of a drug is majorly based on the solubility drugs.Nearly 40% newly developed drugs show poor water solubility.Several approaches are used for increasing such development.Nanosuspension one attractive tactic which can be enhancement solubility, stability as well bioavailability drugs.Nanosuspension defined two-phasic dosage form where solid particles size less than 1 μm dispersed in an aqueous phase with help stabilizer.Particle reduction nanoscale causes increase...

Urolithiasis, commonly known as kidney stones, is characterized by the formation of hard deposits in urinary tract. These stones can cause severe pain and discomfort, their management typically involves a combination medical interventions lifestyle modifications. According to literature, 30% 50% urolithiasis cases recur. Between 9 12% persons industrialised countries are predicted have at some time. Due high frequency stone formation, recurrent nature, prevalence adults, it has significant...

Objective: This experiment was conducted to develop a drying protocol for Withania somnifera roots (during the year 2009–2010 under National Medicinal Plants Board project, B.R. Nahata College of Pharmacy-Scientific Institute Research Organization, Mandsaur [M.P.]).Methods: The were harvested and cut into different sizes (2–4 inches) subjected sun drying, shade hot air oven in temperature ranging from 40°C 60°C. 32°C 42°C during daytime, night hours, samples kept plastic covers prevent...

Litsea glutinosa is popular in tropical and subtropical regions around the world such as India, Japan, Taiwan many parts of China. plant has important medicinal properties it traditionally used for gastrointestinal ailments diseases like abdominal pain, indigestion, diarrhea well gastroenteritis diabetes, edema, traumatic injuries colds, arthritis asthma. also known its essential oil, which provides protective action against so different types bacteria. This antioxidant anti-parasitic...

Niosomes are artificially manufactured vesicles made of Cholesterol and Non-ionic surfactant. Their capacity to encapsulate a broad variety pharmaceuticals shield them from deterioration has piqued interest in drug delivery. have demonstrated possible use the administration anti-tuberculosis medications. Worldwide, tuberculosis is serious public health concern. Even with advances science technology, remains persistent problem.Niosomes can anti-TB drugs, protecting enzymatic degradation...

: One of the most popular sectors in tech and healthcare industries right now is artificial intelligence. In search development new drugs, intelligence essential. Drug design using computer-assisted (CADD) has supplanted traditional approach. Artificial assisting businesses drugs a faster, more affordable, efficient manner, saving money manpower process creating drug molecules to treat any disease. Quantitative structure-activity relationship (QSAR) analysis, activity scoring, silico...

: Chronic wounds generally take a lot of time to recover, which becomes cause worry for the patient and also makes it difficult manage them. wound affects minds millions people worldwide, results in high mortality rate. Nanomedicine has emerged as promising tool addressing this issue chronic wounds. healing holds potential revolutionize care by offering various personalized treatments improving outcomes. Advanced dressings nanofibresscaffolds promote tissue regeneration, accelerates closure....

Targeted drug delivery systems are employed to administer pharmaceutical medication, facilitating the precise of drugs specific diseased areas. Various methods utilize carriers such as antibodies, transdermal patches, biodegradable polymers, nanoparticles (NPs), liposomes, niosomes, and microspheres. Niosomes, on other hand, represent a promising innovative category vesicular systems. Niosomes vesicles formed by hydrating combination nonionic surfactants (NIOs) cholesterol. These surfactant...

Background: This study aims to construct a hydrogel that contains PEG 4000 nanopar-ticles loaded with an extract from Fernandoa adenophylla (FA). Since Adenophylla fruit has been shown have anti-inflammatory and antifungal properties, effort was made increase the extract's effectiveness by forming it into nanoparticulate hydrogel, which may be viable substitute for traditional formulations of providing added advantages transdermal application's superior penetration qualities prolonged...

Abstract: Computer-aided drug design has revolutionized the landscape of discovery, accompanied by a new era innovation and efficiency novel therapeutic agents. This article review explores diverse innovations practical applications that have propelled CADD into forefront modern medicine. CADD, multidisciplinary field at interaction biology, chemistry, computational science, offers toolkit for identification development pharmaceutical compounds. It ability to predict molecular between...

The cosmetics industry is undergoing significant transformations all over the world. Cosmetics regulation in regulated markets significantly stricter terms of quality, safety, nomenclature, and labelling order to govern use cosmetic items. Cosmetic safety governed by a variety regulatory agencies around world, i.e. countries with their own set rules regulations. According recent study, regulations India differ from those such as United States, European Union, Australia. India's market...