Kristi Beshiri

ORCID: 0000-0001-5776-9070
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About
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Research Areas
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Colorectal Cancer Treatments and Studies
  • HER2/EGFR in Cancer Research
  • Lung Cancer Treatments and Mutations
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer, Hypoxia, and Metabolism
  • Lung Cancer Research Studies
  • Neuroendocrine Tumor Research Advances
  • Glioma Diagnosis and Treatment
  • Cancer-related molecular mechanisms research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Melanoma and MAPK Pathways
  • Multiple and Secondary Primary Cancers
  • Sarcoma Diagnosis and Treatment
  • Circular RNAs in diseases
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Reproductive Biology and Fertility
  • Gastric Cancer Management and Outcomes
  • Genetic factors in colorectal cancer
  • Medical Imaging Techniques and Applications
  • Cancer Cells and Metastasis
  • Ferroptosis and cancer prognosis
  • Cancer Treatment and Pharmacology
  • Extracellular vesicles in disease

Institut Gustave Roussy
2023-2024

Ospedale Policlinico San Martino
2018-2021

University of Genoa
2021

<div>AbstractPurpose:<p>This study aimed to explore metabolic tumor volume (MTV) as assessed by 18F-fluorodeoxyglucose positron emission tomography–computed tomography (18F-FDG–PET/CT) and understand its biological meaning in patients with non–small cell lung cancer (NSCLC) exposed immune checkpoint blockers (ICB).</p>Experimental Design:<p>In this study, advanced NSCLC a positive PET scan within 42 days of first-line treatment were enrolled 11 institutions across...

10.1158/1078-0432.c.7631035 preprint EN 2025-01-17

Antibody drug conjugates (ADCs) have revolutionized the treatment of many solid tumours and hematological diseases. Little is known about influence body composition on efficacy safety ADCs. All patients treated with ADCs in early phase clinical trials between 03/2015 03/2023 at Gustave Roussy were retrospectively included. A deep learning software (Anthropometer3DNet) automatically measured anthropometric parameters 3D pretreatment scans, allowing multi-slice measurements muscle mass (MBM),...

10.1016/j.esmoop.2024.102261 article EN cc-by-nc-nd ESMO Open 2024-02-01

Abstract Background: Antibody drug conjugates (ADCs) have revolutionized the treatment of many solid tumours and hematological diseases. Little is known about influence body composition on efficacy safety ADCs. Methods: All patients treated with ADCs in early phase clinical trials between 03/2015 03/2023 at Drug Development Department Gustave Roussy were retrospectively included analysis. A deep learning software (Anthropometer3DNet) automatically measured anthropometric parameters 3D...

10.1158/1538-7445.am2024-6438 article EN Cancer Research 2024-03-22

Abstract INTRODUCTION: Liquid biopsy (LB) proved its clinical utility in advanced non-small cell lung cancer, but role early-stage disease is less clear. Here, we investigated the of LB for molecular diagnosis cancer and correlation with relapse. METHODS: This retrospective, monocentric study collected results from performed patients (pts) an between January 2021 May 2023, within prospective STING (NCT04932525). LBs were executed at different time points (before, after curative treatment, or...

10.1158/1538-7445.am2024-7490 article EN Cancer Research 2024-03-22

Abstract Purpose: This study aimed to explore metabolic tumor volume (tMTV) as assessed 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG-PET/CT), and understand its biological meaning in patients with NSCLC exposed immune checkpoint blockers(ICBs). Experimental Design: In this study, advanced a positive PET scan within 42 days of first line treatment were enrolled 11 institutions across 4 countries. Total MTV was analyzed, 42% SUVmax threshold. Survival...

10.1158/1078-0432.ccr-24-1993 article EN Clinical Cancer Research 2024-10-22

e16506 Background: Small cell carcinoma of the bladder (SCCB) is a rare, highly aggressive, neoplasm without standard treatment protocol. We used Surveillance, Epidemiology, and End Results (SEER) database to study clinical features, prognostic variables, treatment, survival large population-based sample. Methods: The SEER Research Data (2000-2014) were investigated using SEER*Stat software. Patients (pts) with pure or mixed SCCB, T2-T4, any N, M0, who received either surgery radiotherapy...

10.1200/jco.2018.36.15_suppl.e16506 article EN Journal of Clinical Oncology 2018-05-20
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