A5100718949- Kruppel-like factors research
- Fibroblast Growth Factor Research
- Advanced Glycation End Products research
- Circular RNAs in diseases
- Body Composition Measurement Techniques
- Biotin and Related Studies
- Bone and Dental Protein Studies
- Trace Elements in Health
- Nutrition and Health in Aging
- Per- and polyfluoroalkyl substances research
- Diabetes Treatment and Management
- Selenium in Biological Systems
- Heavy Metal Exposure and Toxicity
- Proteoglycans and glycosaminoglycans research
- Effects and risks of endocrine disrupting chemicals
- Endometriosis Research and Treatment
- Parathyroid Disorders and Treatments
- Erythrocyte Function and Pathophysiology
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Obesity, Physical Activity, Diet
Central Hospital of Wuhan
2020
Jinan University
2020
Huazhong University of Science and Technology
2020
Guangdong Province Women and Children Hospital
2020
Nanjing University of Chinese Medicine
2019
Jiangsu Province Hospital
2019
There has been increasing interest in the concept that exposure to environmental chemicals may be contributing factors epidemics of diabetes mellitus (DM). Triclocarban and triclosan (TCs) are synthetic antibacterial widely used personal care products. Studies have shown TCs endocrine disruptors alter metabolic conditions. However, it remains unclear whether is a risk factor for impaired glucose tolerance (IGT) type 2 (T2DM). We explored hypothesis associated with an increased IGT T2DM. To...
Abstract Objectives Circular RNA, a type of RNA formed by covalently closed loop, possesses sophisticated abilities gene regulation in tumorigenesis and metastasis. However, the role circRNAs on lung adenocarcinoma (LUAD) remains largely unknown. Materials methods The cMras was examined both vitro vivo. expression LUAD tissues determined quantitative real‐time PCR (qRT‐PCR). Downstream targets were predicted bioinformatics tools confirmed immunoprecipitation assay luciferase assay. qRT‐PCR...
Background Cognitive decline can develop into mild cognitive impairment, a high-risk factor in the progression of Alzheimer's disease. The antioxidant micronutrient selenium may have some effect on preventing decline, but association between whole blood concentration and function remains controversial.Aim To investigate score elderly Americans.Subjects methods Data was obtained from national health nutrition survey 2011 2014. A general linear model used to adjust for possible risk factors...
This study aims to investigate the association between handgrip strength (HGS) and cardiometabolic disorders (CMD), including hypertension, diabetes, dyslipidemia, in a prospective study. The HGS CMD was examined using data from 5,271 Chinese adult participants ≥45 years old enrolled CHARLS (Chinese Health Retirement Prospective Cohort Study) during 2011-2015. Relative HGS, calculated as maximal absolute both hands divided by body mass index, used primary analysis into three groups according...
The etiology of polycystic ovary syndrome (PCOS) is complex and the pathogenesis not fully understood. Some studies have shown that dysregulation ovarian granulosa cells may be related to abnormal follicles excessive androgen in women with PCOS. Our team has also confirmed high expression status H19 PCOS patients early stage. However, relationship between miR-19b development still unknown. Therefore, we used bioinformatics predict binding sites human miR-19b, CTGF genes. After silencing...
Abstract Background Atherosclerosis (AS) is the basis of cardiovascular diseases, characterized by chronic inflammatory and lipid metabolism disorders. Although anti-inflammatory effect Klotho in AS has been clearly shown, its lipid-lowering unclear. In this study, we examined effects recombinant (Re-KL) protein on accumulation foam cells. Methods THP-1 cells were exposed to 100 nM phorbol myristate acetate for 24 h then oxidized low-density lipoprotein (ox-LDL; 80 mg/mL) induce cell...