Zeev N. Kain

ORCID: 0000-0001-5819-9196
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About
Contact & Profiles
Research Areas
  • Pediatric Pain Management Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Family and Patient Care in Intensive Care Units
  • Music Therapy and Health
  • Anesthesia and Pain Management
  • Infant Development and Preterm Care
  • Anesthesia and Sedative Agents
  • Enhanced Recovery After Surgery
  • Intensive Care Unit Cognitive Disorders
  • Hemodynamic Monitoring and Therapy
  • Anesthesia and Neurotoxicity Research
  • Airway Management and Intubation Techniques
  • Nausea and vomiting management
  • Healthcare professionals’ stress and burnout
  • Childhood Cancer Survivors' Quality of Life
  • Acupuncture Treatment Research Studies
  • Pain Management and Placebo Effect
  • Opioid Use Disorder Treatment
  • Patient Satisfaction in Healthcare
  • Complementary and Alternative Medicine Studies
  • Surgical Simulation and Training
  • Healthcare cost, quality, practices
  • Child and Adolescent Health
  • Infant Health and Development
  • Health Systems, Economic Evaluations, Quality of Life

Yale University
2016-2025

Children's Hospital of Orange County
2016-2025

University of California, Irvine
2016-2025

UC Irvine Health
2017-2024

Walt Disney (United States)
2024

Orange County Healthcare Agency
2022

Chapman University
2021

University of California, Irvine Medical Center
2011-2019

Stanford University
2018

Newport (United States)
2018

Findings from published studies suggest that the postoperative recovery process is more painful, slower, and complicated in adult patients who had high levels of preoperative anxiety. To date, no similar investigation has ever been conducted young children.We recruited 241 children aged 5 to 12 years scheduled undergo elective outpatient tonsillectomy adenoidectomy. Before surgery, we assessed child parental situational anxiety temperament. After all subjects were admitted a research unit...

10.1542/peds.2005-2920 article EN PEDIATRICS 2006-08-01

To determine predictors and behavioral outcomes of preoperative anxiety in children undergoing surgery.A prospective, longitudinal study.A university children's hospital.One hundred sixty-three children, 2 to 10 years age (and their parents), who underwent general anesthesia elective surgery.In the holding area, level child parents was determined using self-reported independent observational measures. At separation operating room, rated again. Postoperative responses were evaluated 3 times...

10.1001/archpedi.1996.02170370016002 article EN Archives of Pediatrics and Adolescent Medicine 1996-12-01

In Brief Based on previous studies, we hypothesized that the clinical phenomena of preoperative anxiety, emergence delirium, and postoperative maladaptive behavioral changes were closely related. We examined this issue using data obtained by our laboratory over past 6 years. Only children who underwent surgery general anesthesia sevoflurane/O2/N2O did not receive midazolam recruited. Children's anxiety was assessed preoperatively with modified Yale Preoperative Anxiety Scale (mYPAS),...

10.1213/01.ane.0000136471.36680.97 article EN Anesthesia & Analgesia 2004-11-17

Both midazolam and parental presence during induction of anesthesia are routinely used to treat preoperative anxiety in children. The purpose this investigation was determine which these two interventions is more effective.Anxiety the child perioperative period primary end point. Secondary points included parent compliance induction. Children (n = 88) were randomly assigned one three groups: (1) 0.5 mg/kg oral midazolam; (2) anesthesia; or (3) control (no premedication). Using multiple...

10.1097/00000542-199811000-00015 article EN Anesthesiology 1998-11-01

Evaluating the effectiveness of interventions directed toward treatment preoperative anxiety in children has been hindered by absence a statistically valid measurement tool.In previous investigation, we developed an instrument (Yale Preoperative Anxiety Scale [YPAS]) that can be used to assess undergoing induction anesthesia. The purpose present investigation was modify and expand applicability holding area validate modified (m-YPAS) against recognized "gold standard" (State-Trait Inventory...

10.1097/00000539-199710000-00012 article EN Anesthesia & Analgesia 1997-10-01

Background Children and parents experience significant anxiety distress during the preoperative period. Currently available interventions are having limited efficacy. Based on an integration of literature in both anesthesia psychological milieus, authors developed a behaviorally oriented perioperative preparation program for children undergoing surgery that targets family as whole. Methods their (n = 408) were randomly assigned to one four groups: (1) control: received standard care; (2)...

10.1097/00000542-200701000-00013 article EN Anesthesiology 2007-01-01

Evaluating the effectiveness of interventions directed toward treatment preoperative anxiety in children has been hindered by absence a statistically valid measurement tool.In previous investigation, we developed an instrument (Yale Preoperative Anxiety Scale [YPAS]) that can be used to assess undergoing induction anesthesia. The purpose present investigation was modify and expand applicability holding area validate modified (m-YPAS) against recognized "gold standard" (State-Trait Inventory...

10.1213/00000539-199710000-00012 article EN Anesthesia & Analgesia 1997-10-01

In Brief OBJECTIVE: To estimate the severity of low back pain (LBP) during pregnancy, including prevalence, risk factors, impact on daily living, and health provider management. METHODS: An anonymous survey consisting 36 questions was distributed to pregnant women participating in various prenatal care clinics educational classes New Haven County, Connecticut. A total 950 surveys returned from May 2002 through October 2003. At each site, a researcher available week answer gather surveys....

10.1097/01.aog.0000129403.54061.0e article EN Obstetrics and Gynecology 2004-07-01

Although some anesthesiologists use oral sedatives or parental presence during induction of anesthesia (PPIA) to treat preoperative anxiety in children, others may these interventions simultaneously (e.g., and PPIA). The purpose this investigation was determine whether approach has advantages over treating children with alone.The child's the throughout perioperative period primary endpoint study. Parental satisfaction secondary endpoint. Subjects (n = 103) were assigned randomly one two...

10.1097/00000542-200004000-00010 article EN Anesthesiology 2000-04-01

We determined whether children who are extremely anxious during the induction of anesthesia more at risk developing postoperative negative behavioral changes compared with appear calm process.Children (n = 91) aged 1-7 yr scheduled for general and elective outpatient surgery were recruited. Using validated measures preoperative anxiety behaviors, evaluated on Postoperative Days 1, 2, 3, 7, 14. a multivariate logistic regression model, in which dependent variable was presence or absence...

10.1097/00000539-199905000-00013 article EN Anesthesia & Analgesia 1999-05-01

The purpose of this study was to determine whether larger doses anesthetics are required in the anxious patient establish and maintain a clinically sufficient hypnotic component anesthetic state. Fifty-seven women undergoing bilateral laparoscopic tubal ligation with propofol-based regimen were enrolled cross-sectional study. Trait (baseline) state (situational) anxiety assessed all patients immediately before surgery, propofol for induction maintenance anesthesia recorded. A bispectral...

10.1097/00000539-199912000-00003 article EN Anesthesia & Analgesia 1999-12-01

Background To determine whether parental presence during induction of anesthesia is an effective preoperative behavioral intervention, a randomized controlled trial with children undergoing outpatient surgery was conducted. Methods Eighty-four were randomly assigned to parent-present or parent-absent group. Using multiple and physiologic measures anxiety, the effect intervention on their parents assessed. Predictors for response examined using multivariate linear regression analysis. Results...

10.1097/00000542-199605000-00007 article EN Anesthesiology 1996-05-01

Music may decrease the anxiety experienced by patients before surgery. Previous studies of this issue were hindered with multiple methodological problems. In investigation, we examined hypothesis while using a rigorous study design and objective outcome measures. Adult undergoing anesthesia surgery randomly assigned to two groups. Subjects in Group 1 (n = 48) listened 30-min patient-selected music session, subjects 2 45) received no intervention. By self-report validated behavioral...

10.1097/00000539-200206000-00021 article EN Anesthesia & Analgesia 2002-06-01

The purpose of this study was to determine whether larger doses anesthetics are required in the anxious patient establish and maintain a clinically sufficient hypnotic component anesthetic state. Fifty-seven women undergoing bilateral laparoscopic tubal ligation with propofol-based regimen were enrolled cross-sectional study. Trait (baseline) state (situational) anxiety assessed all patients immediately before surgery, propofol for induction maintenance anesthesia recorded. A bispectral...

10.1213/00000539-199912000-00003 article EN Anesthesia & Analgesia 1999-12-01

Background To determine whether music influences intraoperative sedative and analgesic requirements, two randomized controlled trials were performed. Methods In phase 1, 35 adults undergoing urologic procedures with spinal anesthesia patient-controlled intravenous propofol sedation randomly assigned to hear favorable via headset or have no music. 2, 43 lithotripsy treatment of renal ureteral calculi receiving opioid analgesia either a no-music group. The effect on sedatives analgesics...

10.1097/00000542-199808000-00005 article EN Anesthesiology 1998-08-01

Although multiple studies document the effect of sedative premedication on preoperative anxiety in children, there is a paucity data regarding its postoperative behavioral outcomes.After screening for recent stressful life events, children undergoing anesthesia and surgery were assigned randomly to receive either 0.5 mg/kg midazolam 15 acetaminophen orally (n = 43) or 43). Using validated measures anxiety, evaluated before after administration intervention during induction anesthesia. On...

10.1097/00000542-199903000-00018 article EN Anesthesiology 1999-03-01

OBJECTIVES & AIM: The purpose of this investigation was to examine children's anxiety across the perioperative setting.Although several studies have examined preoperative in children, few researchers illustrated anxiety; that is, children throughout pre and postoperative continuum.Participants were 261 ages 2-12. Anxiety rated prior surgery, immediately after for 2 weeks at home following surgery.Low child sociability high parent predicted anxiety. Perioperative related pain negative...

10.1111/j.1460-9592.2010.03263.x article EN Pediatric Anesthesia 2010-02-23

We determined whether children who are extremely anxious during the induction of anesthesia more at risk developing postoperative negative behavioral changes compared with appear calm process.Children (n = 91) aged 1-7 yr scheduled for general and elective outpatient surgery were recruited. Using validated measures preoperative anxiety behaviors, evaluated on Postoperative Days 1, 2, 3, 7, 14. a multivariate logistic regression model, in which dependent variable was presence or absence...

10.1213/00000539-199905000-00013 article EN Anesthesia & Analgesia 1999-05-01

The purpose of this controlled study was to provide a description children's postoperative pain, including pain intensity and analgesic consumption.Participants included 261 children, 2 12 years age, undergoing routine tonsillectomy adenoidectomy surgery. Baseline demographic data were collected before surgery, standardized approach anesthesia surgical procedures used. Pain consumption recorded for weeks at home.On the first day home, although parents rated 86% children as experiencing...

10.1542/peds.2008-3529 article EN PEDIATRICS 2009-09-08

Background The minimum time interval between administration of oral midazolam and separation children from their parents that ensures good anterograde amnesia has not been previously determined. This is particular importance in a busy operating room setting where schedule delays secondary to may be tolerated. Methods Children (n = 113) undergoing general anesthesia surgery completed preoperative baseline memory testing using validated series picture cards were randomly assigned one three...

10.1097/00000542-200009000-00016 article EN Anesthesiology 2000-09-01
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