A5050212520- Hemodynamic Monitoring and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Optical Imaging and Spectroscopy Techniques
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Blood Pressure and Hypertension Studies
- Anesthesia and Neurotoxicity Research
- T-cell and B-cell Immunology
- Non-Invasive Vital Sign Monitoring
- Respiratory Support and Mechanisms
- Immune Cell Function and Interaction
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Nausea and vomiting management
- Acute Ischemic Stroke Management
- Meningioma and schwannoma management
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Immunotherapy and Immune Responses
- Glioma Diagnosis and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cancer, Stress, Anesthesia, and Immune Response
- Renal function and acid-base balance
Shenzhen Children's Hospital
2025
Yale University
2016-2025
Indiana University – Purdue University Indianapolis
2023-2025
Indiana University School of Medicine
2023-2025
Institute of Software
2024
Chinese Academy of Sciences
2024
Mayo Clinic
2023
First Affiliated Hospital Zhejiang University
2022
Zhejiang University
2022
Committee on Publication Ethics
2021
The COVID-19 outbreak has led to 80,409 diagnosed cases and 3,012 deaths in mainland China based on the data released March 4, 2020. Approximately 3.2% of patients with required intubation invasive ventilation at some point disease course. Providing best practices regarding for an overwhelming number amid enhanced risk cross-infection is a daunting undertaking. authors presented experience caring critically ill Wuhan. It extremely important follow strict self-protection precautions. Timely,...
Awake craniotomy is currently a useful surgical approach to help identify and preserve functional areas during cortical subcortical tumor resections. Methodologies have evolved over time maximize patient safety minimize morbidity using this technique. The goal of study analyze single surgeon's experience the evolving methodology awake language sensorimotor mapping for glioma surgery.The authors retrospectively studied patients undergoing brain surgery between 1986 2014. Operations initial...
The coronavirus disease 2019, named COVID-19 officially by the World Health Organization (Geneva, Switzerland) on February 12, 2020, has spread at unprecedented speed. After first outbreak in Wuhan, China, Chinese anesthesiologists encountered increasing numbers of infected patients since December 2019. Because main route transmission is via respiratory droplets and close contact, anesthesia providers are a high risk when responding to devastating mass emergency. So far, actions have been...
The pandemic of coronavirus disease 2019 (COVID-19) has several implications relevant to neuroanesthesiologists, including neurological manifestations the disease, impact anesthesia provision for specific neurosurgical procedures and electroconvulsive therapy, health care provider wellness. Society Neuroscience in Anesthesiology Critical Care appointed a task force provide timely, consensus-based expert guidance neuroanesthesiologists during COVID-19 pandemic. aim this document is focused...
We have shown that CD8(+) CTLs are the key mediators of accelerated rejection, and T cells represent prime targets CD154 blockade in sensitized mouse recipients cardiac allografts. However, current protocols require at time sensitization, whereas delayed treatment fails to affect graft rejection recipients. To elucidate mechanisms costimulation blockade-resistant improve efficacy CD154-targeted therapy, we found alloreactive were activated despite hosts. Comparative CD8 cell activation study...
Meng, Lingzhong; Tran, Nam Phuong; Alexander, Brenton S.; Laning, Kathleen; Chen, Guo; Kain, Zeev H.; Cannesson, MaximeAuthor Information
Importance Propofol sedation is widely used for endoscopic procedures, but it poses risks of hemodynamic and respiratory depression. The addition esketamine as an adjuvant may reduce propofol requirements associated adverse events. Objective To evaluate the effects low-dose added to propofol-based on desaturation hypotension during same-visit bidirectional endoscopy. Design, Setting, Participants This multicenter, double-blind, placebo-controlled randomized clinical trial assessed patients...
The association between cerebral desaturation and postoperative delirium in thoracotomy with one-lung ventilation (OLV) has not been specifically studied.A prospective observational study performed thoracic surgical patients. Cerebral tissue oxygen saturation (Scto2) was monitored on the left right foreheads using a near-infrared spectroscopy oximeter. Baseline Scto2 measured patients awake breathing room air. minimum lowest measurement at any time during surgery. hypersaturation were an...
Abstract Acute pancreatitis (AP) remains a significant clinical challenge. Mitochondrial dysfunction contributes significantly to the pathogenesis of AP. Milk fat globule EGF factor 8 (MFG‐E8) is an opsonizing protein, which has many biological functions via binding αvβ3/5 integrins. Ligand‐dependent integrin‐FAK activation STAT3 was reported be great importance for maintaining normal mitochondrial function. However, MFG‐E8's role in AP not been evaluated. Methods Blood samples were acquired...