A5042255335- Sodium Intake and Health
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Diet, Metabolism, and Disease
- Nutrition and Health in Aging
- Liver Disease and Transplantation
- Nutrition, Health and Food Behavior
- Hepatitis C virus research
- Diet and metabolism studies
- Nuts composition and effects
- Lipid metabolism and disorders
- Alcohol Consumption and Health Effects
- Renal function and acid-base balance
- Thermoregulation and physiological responses
- Cholesterol and Lipid Metabolism
- Tea Polyphenols and Effects
- Cancer, Lipids, and Metabolism
- Phytochemicals and Antioxidant Activities
- Restless Legs Syndrome Research
- Migration, Aging, and Tourism Studies
- Mangiferin and Mango Extracts
- Dialysis and Renal Disease Management
- Dietetics, Nutrition, and Education
- GABA and Rice Research
Nakamura Gakuen University
2015-2025
Nishikyushu University
2011-2018
Nutrition Sciences (Belgium)
2011-2014
Kanzaki (Japan)
2012-2014
National Kyushu Medical Center
2008-2012
Clinical Research Management
2009-2010
Kyushu University
2009
Laboratoire des Sciences de l’Information et de la Communication
2008
Academy of Nutrition and Dietetics
2008
Objective. The onset and progression of non-alcoholic fatty liver disease (NAFLD) seem to be affected by nutritive intake; however, detailed examinations have not been performed in non-obese NAFLD patients. purpose this study was identify potential factors that affect its related nutritional problems. Material methods. We investigated the distribution abdominal fat, dietary intake, biochemical data patients with compared obese Results. There no significant difference percentage diabetes or...
Nonalcoholic fatty liver disease (NAFLD) is a common chronic that ranges in severity from simple steatosis to cirrhosis. NAFLD considered be associated with hepatic metabolic disorders, resulting overaccumulation of acids/triglycerides and cholesterol. The pathogenesis progression are generally explained by the "two-hit theory." Most studies lipid metabolism have focused on acids/triglycerides; therefore, impact cholesterol still ambiguous. In this paper, we review recent viewpoint...
We previously studied fatty acid metabolism in the liver of nonalcoholic disease (NAFLD) and reported activation LXRalpha-SREBP-1c pathway hepatocytes. LXRalpha regulates cholesterol as well metabolism, its agonistic ligands are oxysterols. Moreover, there is some evidence that excess intake involved onset NAFLD. Therefore, this study, we examined expression metabolism-associated genes NAFLD by real-time PCR. Expression ACAT1 was up-regulated more noticeable non-obese rather than obese...
Water chestnut (Trapa japonica) is a thorny aquatic floating plant that contains hydrolyzable polyphenols (WCPs) such as eugeniin, 1,2,3,6-tetra-O-galloyl-β-d-glucopyranose (TGG), and trapain. Previous studies have revealed WCPs antioxidant properties can suppress postprandial blood glucose elevation in mice human participants. However, the functionality of treating obesity metabolic syndrome, which become significant issues recent years, remains unclear. Here, we aimed to determine effects...
Postprandial hyperglycemia is a risk factor not only for diabetes mellitus, but also arteriosclerosis. Therefore, controlling the rapid postprandial increase in blood glucose levels necessary. This study aimed to develop mulberry leaf and water chestnut husk tea investigate its effect on levels. We measured polyphenols 1-deoxynojirimycin contents as well antioxidant activity of an vitro experiment. The 30 participants with borderline was investigated randomized, double-blind,...
Aim: Recent studies have shown that lipid metabolic pathways are required for the entry, replication and secretion of hepatitis C virus (HCV). Although little is known about life cycle HCV in humans, activation cholesterol fatty acid biosynthesis may be critical proliferation. Methods: We assessed transcription levels genes essential liver samples obtained from patients with chronic determined their correlations. The serum low‐density lipoprotein (LDL) core antigen were also measured....
The dietary intake of patients with nonalcoholic fatty liver disease (NAFLD) is generally characterized by high levels carbohydrate, fat, and/or cholesterol, and these patterns influence hepatic lipid metabolism in the patients. Therefore, careful investigation habits could lead to better nutrition therapy NAFLD main treatment for chronic hepatitis C (CHC) interferon-based antiviral therapy, which often causes a decrease appetite energy intake; hence, nutritional support also required during...
The aim of this study was to validate the FibroScan system compared with liver histology and serum markers for diagnosis hepatic fibrosis. We also tried determine cut-off levels assess feasibility using values predict fibrosis stage.In 44 patients HCV infection, stiffness evaluated by FibroScan, a biopsy. Associations between these indices were analyzed.FibroScan showed good correlation type IV collagen, hyaluronic acid procollagen-III-peptide, platelet count. Compared histology, increased...
Abstract Recent studies have demonstrated that several cellular factors are involved in entry of hepatitis C virus (HCV) into host cells. Detailed gene expression profiles these HCV‐infected livers not been reported for humans. Transcriptional levels LDL receptor (LDLR), CD81, scavenger class B type I (SR‐BI), claudin‐1, and occludin genes liver samples from patients with chronic were investigated. Serum LDL‐cholesterol (LDL‐C) HCV core antigen also evaluated, claudin‐1 immunohistochemically...
The purpose of this study was to investigate the relationship between salt intake and urinary excretion examine validity a self-monitoring device for estimating 24-h from overnight urine samples.Twelve young, healthy female volunteers consumed test meals days 1 14 estimated on 2-15 by using device. content as follows: 10 g (days 1-5), 6 6-8), 13 9-11), (day 12), 13), 14).The average (the ratio previous day) samples 8.01±1.15 (0.73±0.11) 2-6, 5.86±0.85 (1.01±0.15) 7-9, 9.69±1.64 (0.74±0.13)...
In this study, the authors measured sodium and potassium concentrations in spot urine samples of preschool children on multiple days, evaluated individual, daily, seasonal effects. A total 104 healthy aged 4 to 5 years were studied. Urine collected from first day after waking for three consecutive days (Monday–Wednesday) four times a year (spring, summer, autumn, winter). The estimated daily volume as 500 mL creatinine excretion 300 mg, used these calculate levels. Daily levels ratios highly...
Abstract Objective The present study aimed to evaluate salt-reduction education using a self-monitoring urinary salt-excretion device. Design Parallel, randomized trial involving two groups. following parameters were checked at baseline and endline of the intervention: salt check sheet, eating behaviour questionnaire, 24 h home urine collection, blood pressure before after collection. Setting intervention group self-monitored excretion self-measuring device for 4 weeks. In control group, was...
Abstract To prevent and treat hypertension, it is important to restrict salt in one's diet since adolescence. However, an effective salt‐reduction education system has yet be established. Besides accurate evaluation, we believe that the frequent usage of a measurement device may motivate individuals avoid high intake. The present study evaluated use urinary excretion for parallel randomized trial two groups. sample comprised 100 university students who provided consent participate. A survey...
Underreporting is a problem in dietary surveys, and data on Japanese individuals with obesity are lacking. In addition, surveys of obesity, underreporting extreme energy restrictive practices for short periods time have been reported, blood total ketone levels (ketone bodies) may be able to distinguish between these factors. The present study aimed examine the relationship [energy intake (EI)/basal metabolic rate estimate (BMR)] bodies obese women. participants included 91 women aged 47±9...
Electrical properties estimated from the electrical resistance of human body can serve as indicators muscle tissue status and risk developing sarcopenia; however, to date, at least best our knowledge, no studies have performed such an assessment in older individuals with advanced dementia. The present study examined associations between grip strength, composition using bioimpedance spectroscopy (BIS) women aged 77-97 years residing dementia group homes. A total 33 participants were enrolled...
This study aimed to examine the usefulness of self-monitoring urinary salt excretion for educating individuals about risk excessive dietary intake. The subjects were 30 volunteers (15 men and 15 women) not consuming anti-hypertensive medication. measured at home 4 weeks using a device. Blood pressure (BP), anthropometric variables nutritional (by dietary-habits questionnaire) before after measurement excretion. Statistical analyses performed, including paired t-tests, Chi-square test,...
The authors investigated interannual differences in the sodium excretion levels of young healthy Japanese women as estimated from spot urine analysis at Nakamura Gakuen University 1995 to 2015. Participants included 4931 aged 18 20 years who were classified into three time periods according year health check: first (1995-2001), second (2002-2007), and third (2008-2015). Estimated daily urinary potassium ratio 120.6±31.9 mmol, 35.2±8.1 3.5±0.9, respectively. Adjusted for body weight,...
Malnutrition is an important prognostic factor for patients with liver disease and a novel nutritional assessment tool required these patients. The aim of this study was to validate the Mini Nutritional Assessment (MNA) as screening disease, by comparing MNA scores other nutrition-related parameters.Patients who were hospitalized at gastroenterology division Kyushu Beppu Medical Center enrolled. included 77 (male/female, 46/31; mean±SD age, 68.5±10.7 years; cirrhosis, 64.9%; cancer, 61.0%)....