A5021400482- Blood Coagulation and Thrombosis Mechanisms
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Blood properties and coagulation
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dysphagia Assessment and Management
- Magnetic and Electromagnetic Effects
- Venous Thromboembolism Diagnosis and Management
- Protease and Inhibitor Mechanisms
- Hemophilia Treatment and Research
- Electromagnetic Fields and Biological Effects
- Nutritional Studies and Diet
- Sleep and Wakefulness Research
- Tracheal and airway disorders
- Hemostasis and retained surgical items
- Erythrocyte Function and Pathophysiology
- Platelet Disorders and Treatments
- Cardiovascular and Diving-Related Complications
- Innovations in Medical Education
- Sleep and related disorders
- Vitamin K Research Studies
- Peptidase Inhibition and Analysis
- Sodium Intake and Health
- Cell Adhesion Molecules Research
- Problem and Project Based Learning
Kao Corporation (Germany)
2005-2024
Kyushu University Hospital
1997-2023
Hiroshima University
2021-2023
Nakamura Gakuen University
2009-2021
Aichi Medical University Hospital
2021
Ministry of Health Labour and Welfare
2021
Kao Corporation (Japan)
2020
Nutrition Sciences (Belgium)
2017-2019
Nippon Sport Science University
2018
Kyushu University
1996-2016
Sky (also called Rse, Brt, and Tyro3) is a member of subfamily related receptor tyrosine kinases, including Axl/Ufo/Ark c-Eyk/Mer. We obtained evidence that Gas6 (the product growth arrest-specific gene 6) ligand the kinase. Gas6, but not protein S (an anticoagulant structurally similar to Gas6), specifically bound soluble form (Sky-Fc), composed extracellular domain fused Fc human immunoglobulin G1. The native recombinant S, stimulated phosphorylation ectopically expressed in Chinese...
Editorial-Demko body mass index (BMI) or fail to comply with PAP therapy.Everyone benefits when physicians and dentists collaborate achieve the common goal of providing highest quality care for OSA patients.This journal's publication is no small feat.It has taken nearly two years planning, development, coordination by Editor-in-Chief Leslie C. Dort, DDS, capable staff in national office, who have worked diligently bring journal from a dream reality.Under expert hand Dr. assistance Deputy...
A congenital deficiency of the coagulation Factor XIII subunit (F A) is a rare autosomal recessive disorder that characterized by life-long bleeding tendency complicated difficulty in healing. Thus far, no molecular genetic analysis this has been reported. In study, we demonstrate abnormalities family with disorder. We performed Northern blot peripheral blood monocytes obtained from propositus and found 4-kb single band F mRNA whose size was identical normal subjects. Exons II-XV, which...
We systematically screened for the aetiology of thrombophilia in 115 patients with venous, arterial and small vessel thromboses. Forty-one (36% those we examined) suffering from a variety thromboses, including deep vein thrombosis, pulmonary embolism, occlusion, cerebral infarction, Moyamoya disease ulcerative colitis, were characterized either positive lupus anticoagulants or decreased activities protein S, C, antithrombin III and/or plasminogen. Eight mutation sites confirmed 11 thrombotic...
Venous thromboembolism (VTE) incidence is rising rapidly in Japan with lifestyle westernization and aging. Deficiency of protein S, an important blood coagulation regulator, a risk factor for VTE. Protein S deficiency prevalence Asians approximately 10 times that Caucasians type II deficiency, associated the Tokushima mutation (K155E), quite high Japan. However, currently available methods measuring are not precise enough detection this deficiency. We developed novel assay system...
The authors' study first focuses on the role of ferromagnetic particles in magnetic orientation fibrin polymers. Rod-like were mixed into a solution fibrinogen. polymerization process was exposed to field 8 T. Magnetic agglomerated form chains clusters which oriented parallel fields. polymers did not occur near particles. In possible effects fields fibrinolytic process, dissolution formed due observed. activities evaluated by absorbance changes at 500 nm and plate method. A distinguishable...
In this study, we investigated the possible effects of magnetic fields on fibrinolytic process. Fibrin dissolution was observed and activities were evaluated. First, processes in by fibrin plate method. We gathered solutions from dissolved fibrin, measured mean levels degradation products (FDPs) solutions. Mean FDPs exposed to 8 T higher than those not fields. Second, carried out an experiment understand how oriented a field dissolves. fibrins plates assayed. The result that gels formed at...
Summary Protein S is a vitamin-K-dependent plasma glycoprotein that serves as cofactor for activated protein C in the anticoagulation pathway, which regulates blood coagulation by inactivating factors Va and VIIIa. Mechanisms regulating expression of gene remain unknown to date. The aim this study was characterize cis-acting DNA elements human liver. We found liver cell lines (HepG2 PLC) transcribed mRNA, whereas non-liver (HEK293 HeLa cells) either weakly or not at all. Isolation analysis...