A5090986107- Pain Mechanisms and Treatments
- Organ Donation and Transplantation
- Hip and Femur Fractures
- Cancer, Stress, Anesthesia, and Immune Response
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Neuropeptides and Animal Physiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Organ Transplantation Techniques and Outcomes
- Medical Imaging Techniques and Applications
- Frailty in Older Adults
- Pain Management and Opioid Use
- Pediatric health and respiratory diseases
- Advanced MRI Techniques and Applications
- Intraoperative Neuromonitoring and Anesthetic Effects
- Scoliosis diagnosis and treatment
- Anesthesia and Pain Management
- Respiratory Support and Mechanisms
- Pharmacological Effects and Toxicity Studies
- Lanthanide and Transition Metal Complexes
University of Science and Technology of China
2023-2025
CAS Key Laboratory of Urban Pollutant Conversion
2025
University of Michigan
2022
Living kidney transplantation is a common treatment for end-stage renal disease. The impact of anaesthetics on postoperative biomarkers injury in living transplant donors not well understood. 70 who underwent extraction were randomly assigned to following two groups: sevoflurane (S group) and propofol (P group). Urine blood collected before induction 1, 2, 6 days after operation. Kidney marker-1 (KIM-1), interleukin-18 (IL-18) tissue inhibitor metalloproteinase-2 (TIMP-2) measured by...
Ciprofol is a recently developed short-acting gamma-aminobutyric acid receptor agonist with higher potency than that of propofol. As new sedative drug, there are few clinical studies on ciprofol. We sought to examine the safety and efficacy ciprofol use for general anesthesia in neurosurgical individuals undergoing surgery intraoperative neurophysiological monitoring (IONM).
Background The role of nerve growth factor (NGF)/tyrosine kinase A receptor (TrKA) signaling, which is activated in a variety pain states, regulating membrane-associated δ-opioid (mDOR) expression poorly understood. hypothesis was that elevated NGF bone cancer tumors could upregulate mDOR spinal cord neurons and agonism might alleviate pain. Methods Bone (BCP) induced by inoculating Lewis lung carcinoma cells into the femoral marrow cavity adult C57BL/6J mice both sexes. Nociceptive...
Frailty, representing the physiological reserve and tolerance of body, serves as a crucial evaluation index overall status older adults. This study aimed to investigate prevalence preoperative frailty its impact on postoperative outcomes among adults with lumbar degenerative disease in China.
Purpose: This study aimed to investigate the value of Pain Sensitivity Questionnaire (PSQ) for prediction postoperative pain and relationship between sensitivity in kidney donors undergoing living-related transplantation. Patients Methods: A total 148 were selected preoperative questionnaire was administered day before surgery. Kidney assigned low PSQ group (PSQ < 6.5, n = 76) or high ≥ 72). The primary endpoint number patient-controlled analgesia (PCA). Other outcomes included: incidence...
<b>Background:</b> Clinically important deterioration (CID) is a composite endpoint that evaluates key clinical features of chronic obstructive pulmonary disease (COPD), and can provide useful information on treatment effects among patients with variable presentations COPD. <b>Aim:</b> To assess the impact budesonide/glycopyrronium/formoterol fumarate dihydrate (BGF) triple therapy vs dual therapies CID in ETHOS. <b>Methods:</b> In ETHOS (NCT02465567), ≥1 moderate/severe exacerbation prior...
<b>Rationale:</b> Nebulizers are an alternative to handheld devices for providing inhaled therapy. We identified factors and trends associated with nebulizer use in SPIROMICS. <b>Methods:</b> SPIROMICS is a prospective cohort study 2,981 enrolled participants across four strata, both never-smokers smokers without COPD. stratified logistic linear mixed models analyze among tobacco-exposed subjects preserved spirometry (TEPPS) those COPD at enrollment visit 1 (V1) after 4-7 years of follow-up...