- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Abdominal vascular conditions and treatments
- Advanced Glycation End Products research
- Pancreatitis Pathology and Treatment
- Graphite, nuclear technology, radiation studies
- Aortic Disease and Treatment Approaches
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Transplantation: Methods and Outcomes
- Congenital Heart Disease Studies
- Congenital Anomalies and Fetal Surgery
- Aortic aneurysm repair treatments
- Vasculitis and related conditions
- Renal Transplantation Outcomes and Treatments
- Nuclear and radioactivity studies
- Orthopaedic implants and arthroplasty
- Body Contouring and Surgery
- COVID-19 and healthcare impacts
- Healthcare Systems and Public Health
- COVID-19 diagnosis using AI
- Bariatric Surgery and Outcomes
- Abdominal Trauma and Injuries
Columbia University Irving Medical Center
2019-2025
Columbia University
2021-2024
Donetsk National Medical University
2024
Morgan Stanley Children's Hospital
2024
Children's Hospital of Philadelphia
2020-2021
Institute of Biomedical Problems
2015
Abstract Aims Bioprosthetic heart valves (BHVs), made from glutaraldehyde-fixed heterograft materials, are subject to more rapid structural valve degeneration (SVD) in paediatric and young adult patients. Differences blood biochemistries propensity for disease accelerate SVD these patients, which results multiple re-operations with compounding risks. The goal of this study is investigate the mechanisms BHV biomaterial present models studying patients juvenile animal models. Methods We...
Single lung transplant (SLT) is an acceptable treatment modality for certain patients with end stage disease. SLT occurs when two appropriate donor lungs are split between recipients ("split singles") or one adequate and the other declined ("isolated single"). There a paucity of literature investigating outcomes in who received isolated SLT. This study analyzes characteristics survival recipients. The database at our institution was queried all transplants 2010 2021. primary outcome assessed...
Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a therapy for patients with refractory respiratory failure. The decision to decannulate someone from (ECMO) often involves weaning trials and clinical intuition. To date, there are limited prognostication metrics guide decision-making determine which will be successfully weaned decannulated.
Bioprosthetic heart valves (BHV), made from glutaraldehyde-fixed xenografts, are widely used for surgical and transcatheter valve interventions but suffer limited durability due to structural degeneration (SVD). We focused on metabolic syndrome (MetS), a risk factor SVD highly prevalent phenotype in patients affected by valvular disease with well-recognized cluster of comorbidities. Multicenter patient data (N = 251) revealed that MetS were at significantly higher accelerated required BHV...
Structure and rate of the overall incidenc mental diseases law enforcement officers in Russia are analyzed for period from 2018 to 2023. Forecast their incidence is calculated 2024–2025 using logistic regression techniques.
Revised guidelines clarify indications for extracorporeal membrane oxygenation (ECMO) support in Coronavirus disease 2019 (COVID-19) patients with acute respiratory distress syndrome (ARDS). Limited data exist to compare clinical outcomes of COVID-19 ARDS non-COVID-19-related when supported ECMO. An observational propensity-matched study was performed and ECMO-related complications between COVID-19-related (COVID) (Control). COVID- cannulated from March 1st, 2020, through June 2021, were...
Abstract Background Aortic dissection and aneurysm are the result of altered biomechanical forces associated with structural weakening aortic wall caused by genetic or acquired factors. Current guidelines recommend replacement ascending aorta when diameter is >5.5 cm in tricuspid valve patients. Aortopathies stress stiffness as well endothelial cell dysfunction synthetic vascular smooth muscle (VSMC) phenotype. We reported that these mechanisms mediated glycoxidation products [Reactive...
<sec> <title>BACKGROUND</title> Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a therapy for patients with refractory respiratory failure. The decision to decannulate someone from (ECMO) often involves weaning trials and clinical intuition. To date, there are limited prognostication metrics guide decision–making determine which will be successfully weaned decannulated. </sec> <title>OBJECTIVE</title> This study aims assist clinicians the patient ECMO, using Continuous Evaluation...
Background: The extracorporeal membrane oxygenation (ECMO) flow rate needed to adequately support patients with acute respiratory distress syndrome (ARDS) is variable. Meeting the oxygen delivery needs of these occasionally requires higher than average thus necessitating insertion an additional drainage cannula. This study addresses frequency which ARDS on ECMO require cannula and whether this need related initial selection. Flow dynamics before after reconfiguration are analyzed. Methods:...
Background: Revised guidelines clarify indications for extracorporeal membrane oxygenation (ECMO) support in patients with COVID-19-related acute respiratory distress syndrome (ARDS). Commercially available ECMO analytics software records granular perfusion data continuously throughout the run. To date, electronic-medical record (EMR) clinical has not been integrated and analyzed machine learning-based algorithms to improve patient care. Methods: Retrospective chart review was performed on...