A5079865531- Microfluidic and Bio-sensing Technologies
- Redox biology and oxidative stress
- Microfluidic and Capillary Electrophoresis Applications
- Radioactive element chemistry and processing
- Lanthanide and Transition Metal Complexes
- Free Radicals and Antioxidants
- Antifungal resistance and susceptibility
- Chemical Synthesis and Characterization
- Advanced optical system design
- Catalytic Processes in Materials Science
- Medicinal Plants and Neuroprotection
- Biosensors and Analytical Detection
- Nanoplatforms for cancer theranostics
- Bioactive Compounds and Antitumor Agents
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Advanced Photocatalysis Techniques
- Catalysis and Oxidation Reactions
- Electrocatalysts for Energy Conversion
- Bacterial Identification and Susceptibility Testing
- Metal-Catalyzed Oxygenation Mechanisms
- Synthetic Organic Chemistry Methods
- Luminescence Properties of Advanced Materials
- Antibiotics Pharmacokinetics and Efficacy
- Sepsis Diagnosis and Treatment
Shanghai Ocean University
2025
Texas Tech University
2021-2024
Xuzhou Medical College
2023-2024
Sir Run Run Shaw Hospital
2022-2024
Zhejiang University
2016-2024
Huazhong University of Science and Technology
2023
Tiangong University
2022-2023
Fujian Normal University
2023
Kunming University of Science and Technology
2023
Dalian University of Technology
2020-2022
Abstract Energy‐harvesting electronic skin (E‐skin) is highly promising for sustainable and self‐powered interactive systems, wearable human health monitors, intelligent robotics. Flexible/stretchable electrodes robust energy‐harvesting components are critical in constructing soft, wearable, energy‐autonomous E‐skin systems. A stretchable tactile interface demonstrated using liquid metal nanoparticles (LM‐NPs)‐based electrodes. This relies on triboelectric nanogenerator composed of a...
Coumarin (1,2-benzopyrone), an aromatic oxygen-containing heterocyclic compound, has various biological functions. Previous studies have demonstrated that coumarin and its derivatives exhibit antifungal activity against Candida albicans. In this study, we investigated the exact mechanism by which works fungus using Annexin V-FITC/PI double staining, TUNEL assay, DAPI found it induced a series of apoptotic features, including phosphatidylserine (PS) externalization, DNA fragmentation, nuclear...
Since the outbreak of coronavirus disease 2019 (COVID-19), countries around world have suffered heavy losses life and property. The global pandemic poses a challenge to public health system, organizations are actively looking for ways quickly efficiently screen viruses. Point-of-care testing (POCT), as fast, portable, instant detection method, is great significance in infectious detection, screening, pre-disease prevention, postoperative treatment, other fields. Microfluidic technology...
Piperlongumine, a natural alkaloid substance extracted from the fruit of long pepper (Piper longum Linn.), is known to inhibit cytosolic thioredoxin reductase (TXNRD1 or TrxR1) and selectively kill cancer cells. However, details mechanism inhibition by piperlongumine against TXNRD1 remain unclear. In this study, based on classical DTNB reducing assay, irreversible recombinant was found showed an apparent kinact value 0.206 × 10−3 µM−1 min−1. Meanwhile, compared with wild-type (-GCUG),...
As the prevalence of systemic fungal infections caused by Candida albicans gradually increases, it is necessary to explore potential and effective antifungals. Carvacrol reported be lethally toxic C. albicans, involving several mechanisms. However, form specific mechanism cell death this compound has not been delineated. In study, we found that carvacrol could significantly decrease survival rates, consistent with previous researches. Further examination proved treatment membrane...
Damaged skin is susceptible to invasion by harmful microorganisms, especially
Many studies have reported that hypocrellin A (HA) exhibits effective antimicrobial activities with proper irradiation. However, its antifungal activity and the involved mechanism not been fully defined. In this study, HA-mediated cytotoxicity in Candida albicans cells was evaluated after photodynamic therapy (aPDT). The results showed 1.0 μg/ml HA significantly decreased survival rate of C. light illumination. Moreover, ROS levels were also remarkably elevated by HA. Further study found...
Abstract Although the productivity–biodiversity relationship (PBR) has been a hot topic, few studies have considered how anthropogenic pressures affect PBRs in marine microzooplankton. Here, we provide first insights into tintinnid assemblages using 18‐yr data from Jiaozhou Bay, typical coastal bay Yellow Sea. We hypothesized and verified that vary across contrasting nutrient inputs functional phylogenetic diversity would deliver more information than conventional species richness. High...
We present a large-area luminescent down-shifting layer consists of polyvinyl alcohol embedding newly synthesized ternary Eu<sup>3+</sup> complex. C-Si solar cell coated with this displayed an enhancement ~15% in external quantum efficiency.
This review correlates lanthanide-ion affinities with the polarizability of donor atoms on immobilized ligands to gain an insight into design lanthanide-selective polymer-supported reagents. Comparison for actinide ions clarifies correlation. Polymers different are classified four categories, based increasing order atom polarizability: oxygen, oxygen and nitrogen, sulfur. Hard−soft acid−base theory is important determinant ion−ligand affinities. Additional factors that affect complexation...
Thioredoxin reductase 1 (TrxR1 or TXNRD1) is a major enzyme in cellular redox regulation and considered as drug target for cancer therapy. Previous studies have reported that plumbagin caused reactive oxygen species (ROS)-dependent apoptosis via inhibiting TrxR1 activity being reduced by TrxR1, leading to selectively cell death. However, the mechanism of TrxR1-mediated cycling obscure evidence targeting still lacking. Herein, we demonstrated catalyzed reduction both selenocysteine...
Nanocrystalline transition metal carbides (TMCs, M = Ti, Zr, Hf, Nb and Ta) have been synthesized by direct electrochemical reduction of solid mixture precursors composed oxides graphite powder (TMOs-C) in molten CaCl2 at 850°C. The synthesis temperature is much lower than that the conventional carbothermic process. SEM analysis showed particle sizes as-prepared TMCs powders were about 15–30 nm. formation processes nanocrystalline monitored analyzing partially reduced samples confirmed to be...
Red and processed meat consumption has been positively related to an increased risk of diabetes in Western populations. However, the results remain inconclusive within Asian populations.This dose-response meta-analysis prospective cohort studies conducted East populations reveals a positive relation between diabetes. Furthermore, U-shaped association was identified unprocessed red diabetes.This research presents substantive evidence advocating for reduction as viable strategy mitigating
Stiff, viscoelastic hydrogels have been fabricated from hydrophobically modified poly(acrylamide-co-sodium acrylate) (HRAM). These materials are macroscopically homogeneous but microscopically heterogeneous, containing hydrophobic aggregates that bridge polymer chains in a three-dimensional network. The charge level at which the dynamic storage modulus is maximized for given concentration corresponds closely with giving maximum hydrophobicity of aggregates, suggesting link between mechanical...
Salicylic acid (SA) is an important plant hormone involved in the activation of defense responses against environmental stresses. However, there are still large unsolved mysteries about how SA pretreatment affects establishment stress tolerance. In this study, application at different concentrations and times were conducted to investigate their effects on response Arabidopsis seedlings salt stress. The with 10 or 20 μM for more than 6 h promoted resistance On other hand, 200 reduced...
Sepsis is a serious medical condition that arises from runaway response to an infection, which triggers the immune system release chemicals into bloodstream. This can result in widespread inflammation throughout body, may cause harm vital organs and, more severe cases, lead organ failure and death. Timely accurate diagnosis of sepsis remains challenge analytical diagnostics. In this work, we have developed validated detection device, utilizing 3D printing technology, incorporates multiple...
The mechanism of ionic recognition by polymer-supported reagents is probed with cross-linked polystyrene modified tetramethylmalonamide (TMMA) ligands. substrates are lanthanide ions in 0.001-8 M HCl and HNO(3) solutions. results fall into three regions acid concentration: low, mid, high. In HCl, distribution coefficients low 0.001 to 2 M, increase 4 6 then decrease 8 HCl. the low-acid region, metal ion remains its waters hydration does not coordinate carbonyl oxygens. As concentration...