A5063726596- Analytical Methods in Pharmaceuticals
- Shoulder and Clavicle Injuries
- Analytical Chemistry and Chromatography
- Trace Elements in Health
- Pulmonary Hypertension Research and Treatments
- Orthopedic Surgery and Rehabilitation
- Cardiovascular and Diving-Related Complications
- Kawasaki Disease and Coronary Complications
- Renal cell carcinoma treatment
- Otolaryngology and Infectious Diseases
- Dermatologic Treatments and Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Tuberous Sclerosis Complex Research
- Streptococcal Infections and Treatments
- Long-Term Effects of COVID-19
- Plant Micronutrient Interactions and Effects
- Coronary Artery Anomalies
- Cardiovascular and exercise physiology
- Exercise and Physiological Responses
- Dermatology and Skin Diseases
- Infectious Diseases and Tuberculosis
- COVID-19 Clinical Research Studies
- Traumatic Ocular and Foreign Body Injuries
- Herbal Medicine Research Studies
- Congenital Anomalies and Fetal Surgery
Atatürk University
2018-2022
Van Yüzüncü Yıl Üniversitesi
2012-2018
While the COVID-19 disease progresses mildly or asymptomatically in some people, its progression is severe and symptomatic others, it an issue that requires a scientific response regarding disease. The present study includes 60 people infected with COVID-19, cases were divided into following groups: asymptomatic, mild, moderate, severe. Serum Zn, Se, Cu levels of these groups analyzed by ICP-MS. All measurements patients compared those 32 healthy individuals. When patient group control...
Background: The authors studied the alterations in mean platelet volume, neutrophil-to-lymphocyte ratio, and red blood cell distribution width values together with count hospitalized patients diagnosed Fournier gangrene to determine their association disease prognosis. Methods: Records of were analyzed retrospectively. Results: Seventy-four (49 men 25 women) a age 57.60 ± 15.34 years (range, 20 95 years) included. Sixty-eight participants discharged six died during follow-up. In group,...
Chronic urticaria (CU) is a common disease characterized by the development of recurrent itchy blisters and/or angioedema lasting longer than 6 weeks. The evidence-based diagnosis CU described in most recent guideline. Metabolomics has potential to offer diagnostic biomarkers for detection and prognosis diseases predict efficacy safety pharmaceutical interventions. Determining variation metabolites found plasma patients (n = 20) 20 controls therefore been goal this investigation. Samples...
A rapid, simple, and sensitive UPLC-MS/MS method was developed validated for the determination of etodolac in rat plasma using flurbiprofen as an internal standard (IS). Etodolac IS were detected electrospray ionization negative ion multiple reaction monitoring mode by transitions (precursor to product) m/z 286.2→212.1 243.2→199.2, respectively. The new extraction procedure does not contain more than one stage. Chromatographic separation performed on reverse phase C18 column with a gradient...
Eser elementler vücudun düzgün çalışması için gereklidir. Biyolojik element konsantrasyonundaki değişiklikler çok sayıda patolojik durumda gözlenmiştir. Bu çalışmanın amacı, larenks dokularındaki eser konsantrasyonunun değerlendirilmesidir. Çalışmada kanseri teşhisi konmuş 9 hastanın kanserli dokuları ve aynı hastaların sağlıklı larekns kullanılmıştır. Larenks Al, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Ag, Cd, Sb Pb seviyeleri, Endüktif Eşleşmiş Plazma Kütle Spektrometresi (ICP-MS) kullanılarak...
Ibuprofen (IBU) is a non-steroidal anti-inflammatory drug that extensively prescribed. For the determination of IBU in pharmaceutical formulations, sensitive, simple, accurate, and rapid ultra-performance liquid chromatography method combination with tandem triple quadruple mass spectrometry (UPLC-MS/MS) has been used validated. The chromatographic separation was accomplished using C18 UPLC column, 95 Å, 2.1 x 50 mm, 1.8 µm, 0.1 percent formic acid conjunction acetonitrile (25:75 v/v. flow...
Bor, hayvan ve insan biyolojisi için çok önemli olan dinamik bir eser elementtir. Bor sitrat, borun metabolizmaya alımındaki en yaygın formlardan biridir. Bu çalışmada oral olarak bor sitrat uygulanan ratların hem plazmalarında de serumlarında ICP-MS yöntemi ile miktarı tayin edilmiş 20 mg/kg ratlardan farklı zamanlarda alınan serum plazma numunelerindeki konsantrasyonları edilerek zamana göre değişim grafiği incelenmiştir. ugulandıkdan sonra 0,25. saatte seviyesinin maksimuma ulaştığı, 48....
Macitentan is an endothelin receptor antagonist drug used in the treatment of pulmonary arterial hypertension (PAH). PAH defined as a serious disease arteries (pulmonary arteries) that connect lungs to heart. The aim our study develop and validate new, sensitive, simple, accurate reliable UV spectrophotometric method for quantification macitentan human plasma. Using wavelength 269 nm, was quantitatively analyzed. For standard solution concentrations 1–30 μg/mL plasma 2–30 μg/mL,...