Osteoporosis is a major public health problem associated with many factors, and it affects more than 50% of women over 50 years old. In the current study, our purpose was to investigate effects phosphodiestarase-5 inhibitors on osteoporosis via nitric oxide/3′,5′-cyclic guanosine monophosphate/protein kinase G signalling pathway. A total female albino Wistar rats were separated into five groups. The first group appointed as healthy control no ovariectomy. All animals in other groups...

This study aimed to investigate the possible protective effect of paricalcitol on experimental amikacin-induced nephrotoxicity model in rats. Wistar albino rats (n = 32) were allocated into four equal groups eight each, control (Group C), P), A), and paricalcitol-treated A + P) groups. Paricalcitol was given intra-peritoneally at a dose 0.4 μg/kg/d for 5 consecutive days prior induction nephrotoxicity. Intra-peritoneal amikacin (1.2 g/kg) used induce day 4. Renal function parameters,...

Antioxidant enzymes play an important role in body defense and free radical removal. Cephalosporins are β-lactam antibiotics. In this work, the effects of cefazolin, cefuroxime cefoperazone which cephalosporins on some selected antioxidant enzyme levels malondialdehyde (MDA) as lipid peroxidation product were investigated kidney, liver, brain tissues albino female rats. Ninety-six rats randomly divided into 16 groups equal number (n = 6). 50 mg/kg 25 cefuroxime, 100 injected...

This study was conducted to investigate the effects of chronic fluorosis on trace elements and vitamin levels in goats. Thirty-three goats exhibiting clinical signs 10 healthy from same region were used. Animals with divided into 2 groups according their age as 1-3 years old 4-6 old. Blood samples collected all Fluoride concentrations determined an ionometer. Na, K, Cl measured ion-selective equipment serum mineral substance obtained by atomic absorption spectrophotometer. Ca, Mg, P...

Hearing loss can occur in newborns exposed to high-level noise; noise exposure cause more physiological stress and lead DNA damage. This study was designed determine damage newborn rats sound at different concentrations. For this purpose, 28 (3-6 days old) were divided into four groups of 7 each group (Control Groups 40 decibel (dB), 70 dB, 110 dB]. In the experimental groups, dB (7.5-15 kHz) applied for 30 min a day days. levels serums obtained from determined by enzyme-linked immunosorbent...

Tularemia has become a re-emerging zoonotic disease in Turkey recently. The aims of this study were to determine the seroprevalence tularemia humans and their animals living rural risky areas our region investigate risk factors. Between January July 2012, people Van province (located at eastern part Turkey) domestic included study. sample size was determined by using cluster sampling method like an event with known prevalence planned as cross-sectional epidemiological Proportional random...

In this study, the cardiac effects of anemia and venous thromboembolism (VTE), reportedly caused by hemolyzed erythrocytes occurring in sheep with babesiosis, were investigated using markers D-dimer (DD). The study included 34 sheep: 24 infected Akkaraman (1-3 years old, diagnosed babesiosis based on clinical laboratory findings) a control group 10 noninfected healthy same breed age. Hematocrit (Hct) levels measured blood obtained from both groups. Cardiac troponin I (cTnI), creatine...

Objective: Worldwide, phytotherapy methods acquire great importance, and studies in this field are increasing their importance each day. This study, it was aimed to examine total antioxidant, oxidant status, oxidative DNA damage, glucose hemoglobin A1c levels the effects of barley grass juice on these parameters rats with diabetes mellitus. Material Method: Four groups were formed for study 6 male weighing 250-350 g used group. Control Group; physiological saline injected via...

Objective: Doxorubicin is a potent antineoplastic agent used in the chemical treatment of cancer. However, due to their cardiotoxic effects, its use limited and currently subject for extensive research. Cardiomyopathy caused by doxorubicin still remains as major concern this drug. This study was aimed contribute issue which needs novel preventive side effect. Materials Methods: Boron boron-containing molecules are medical research properties such antioxidant nature. They tested various...

Advanced age, called geriatrics, negatively affects the aging–related physiological changes on bodysystems. non–steroidal anti–inflammatory drugs (NSAIDs) used in geriatric pets or humans have negative effects kidneys. For this purpose, , of Meloxicam and Flunixin Meglumine, which are NSAIDs frequently Veterinary Medicine, liver kidney structure function male rats were evaluated. Twenty–four (30–36 month old) twenty–four 3–month–old young Wistar albino study. Six groups created, with eight...

This study was carried out to reveal the importance of procalcitonin, C reactive protein, nitric oxide levels, and adenosine deaminase activity in diagnosis prognosis disease naturally infected sheep with Babesia ovis. Thirty diagnosed clinically parasitologically as having ovis were allocated 2 groups. The first group treated only imidocarp dipropionate second flunixine meglumin. On seventh day after treatment, blood samples collected again from babesiosis-infected treatment responses...

Many health problems are seen due to aging. One of these is in the reproductive system. Reproductive system caused by lower urinary symptoms, prostate diseases, low fertility, testicular dysfunction. The aim this study was compare parameters geriatric (3 years old) and young months rats. A 3-year-old rat equivalent an average 90-95-year-old human. For purpose, sperm analysis, histopathology, oxidative stress were examined In analysis results, it determined that motility ratio decreased...

The aim of this study was to determine Neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), cystatin C (Cyc-c), and interleukin-18 (IL-18) levels which are frequently used as biomarkers in geriatric rats compare with those young rats. For purpose, 12 Wistar albino (30-36 months old) (six males six females) (2-3 were study. 24-hour urine samples all groups collected, blood collected for biochemical analysis under anesthesia. mean body weight the statistically...

In this study, the effect of used immunostimulating drugs with FMD vaccine on immunoglobulins was aimed to investigate in sheep. For purpose 40 healthy sheep were divided into 4 groups. Blood and serum samples taken from all animals 0 days before study. measured immediately, IgA, IgG, IgM, IgE Zn values biochemical parameters stored for measurement. Group I applied only vaccine, group II Levamisole III Zinc last IV AD3E vaccine. After 21 days, blood groups again hematologic compared...

Cryptosporidium is a protozoon of zoonotic importance causing infections with diarrhoea and other clinical symptoms in man, domestic, wild animals.The present study was conducted to determine the prevalence cryptosporidiosis diarrhoeic calves which were up 1 month old Van, Turkey, using Kinyoun's acid-fast Nested PCR methods.In this A total 164 faecal samples collected from diarrheic at different farms located Turkey during January 2019 September 2019.The stained method then examined...

This study aimed to determine the levels of homocysteine and cardiac markers in cows with hypocalcemia. research was conducted a total 20 cows, including 10 hypocalcemia healthy controls. Hypocalcemia diagnosed by determining low blood calcium (Ca) levels, standard treatment initiated those disease. Blood samples were taken before again 12 h after treatment, there no significant difference between groups. Ca, ionized (Ica), magnesium (Mg), phosphorus (P) lower, while troponin I (cTnI),...