Objective: To determine levels of trace elements [copper (Cu), zinc (Zn), selenium (Se), and cobalt (Co)] heavy metals [arsenic (As), mercury (Hg), lead (Pb), cadmium (Cd)] in the plasma mothers infants investigate relationship between those neural tube defects (NTD).Methods: A total 100 neonates diagnosed with NTD placed Neonatal Intensive Care Unit Yuzuncu Yil University, Turkey May 2013 December 2016 comprised study group. The control group consisted 70 healthy not or any other congenital...

Aim: Liver and kidney are exposed to a lot of oxidant substances that both from exogen endogen sources. The aim this study was investigate the antioxidant effects C vitamine, Melatonine (MLT) N-acetylcystein (NAC) in carbon tetrachlorur (CCl4) induced oxidative stress mouse. Methods: involved 6 groups; control group (Group 1), CCl4 2), + vitamine 3), MLT 4), NAC 5) combined (CCl4 NAC) 6) with each containing 10 mice. Starting 4th day 0,4 ml/kg were given intraperitoneally (i.p.) all groups...

Venous thromboembolism has multifactorial origin and occurs in the context of complex interactions between environmental genetic predisposing factors. Oxidative stress plays an important role physiopathology venous thrombosis. Current study examined oxidative asymmetric dimethylarginine development DVT with parameters such as serum malondialdehyde (MDA), glutathione peroxidase (GSH-Px), catalase, ADMA, homocysteine, folic acid, vitamin B 6 , 12 levels. Serum MDA levels were found...

Background/aim: The purpose of this study is to evaluate serum pentraxin-3 (PTX-3) levels in Sars-CoV-2 virus infection (COVID-19) patients and investigate whether PTX-3 predicts the disease prognosis. Materials methods: This was conducted on 88 confirmed COVID-19 who were hospitalized due symptomatic pneumonia between April 15 August 15, 2020. divided into two groups as survived non-survived patients. Both compared according demographic features, comorbid conditions measurement other...

It has been reported that many modifications occur with the increase of oxidative stress during storage in erythrocytes. In order to delay these negative changes, we evaluated whether addition substances likely protect antioxidant capacity stored blood would be useful. Therefore, investigated effects resveratrol, tannic acid, and caffeic acid lipid peroxidation erythrocytes blood. Donated was taken into four CPD containing bags. One bag used as control, others were supplemented (30 μ g/mL),...

Abstract Background: Activation products from neutrophils and the complement system might cause endothelial dysfunction, which is central to aetiology of pre‐eclampsia. This study aimed investigate activity myeloperoxidase (MPO), its association with advanced oxidation protein (AOPP), in women pre‐eclampsia eclampsia. Materials method: Twenty‐one pregnant pre‐eclampsia, 11 eclampsia 19 healthy were studied. Serum levels malondialdehyde (MDA), AOPP, ascorbic acid (AA) activities MPO catalase...

We have investigated the effects of active and passive smoking on renal functions in terms glomerular filtration rate, microalbuminuria, β-2 microglobulin excretion.The volunteers included this study were classified into three groups as smokers (n = 24), 20), controls 20). Blood urine samples collected from all groups. Serum glucose, urea, creatinine, cotinine levels blood measured. Also, microalbumin, microglobulin, creatinine measured samples.Serum found to be higher both when compared...

Osteoporosis is a major public health problem associated with many factors, and it affects more than 50% of women over 50 years old. In the current study, our purpose was to investigate effects phosphodiestarase-5 inhibitors on osteoporosis via nitric oxide/3′,5′-cyclic guanosine monophosphate/protein kinase G signalling pathway. A total female albino Wistar rats were separated into five groups. The first group appointed as healthy control no ovariectomy. All animals in other groups...

BACKGROUND Oxidative DNA damage is associated with male infertility. The aim of this study was to evaluate the oxidative sperm cells and blood leukocytes determine levels MDA NO in seminal plasma idiopathic infertile men. MATERIAL AND METHODS enrolled 52 patients, including 30 22 fertile MDA, NO, 8-OHdG/106dG were estimated using spectrophotometry high-pressure liquid chromatography (HPLC)-based methods plasma. association parameters assessed, particularly counts motility. RESULTS mean...

ObjectivesWarts are abnormal skin growths caused by human papilloma virus (HPV) infections within the of patients. Genital warts usually appear in perianal and perigenital regions. Asymptomatic may be activated after years damage natural immunity. The inflammation that occurs during this process lead to an imbalance between prooxidant antioxidant systems. aim study was investigate erythrocyte glutathione peroxidase (GSH-Px) activity, serum paraoxonase enzyme levels, oxidative stress levels...

Abstract Increased oxidative stress is a well‐known phenomenon in dialysis patients. However, the contribution of hypertension to peritoneal patients has not yet been assessed. The present study aimed investigate if had an additional effect on A total 50 treated with were divided into two groups: mean last three blood pressure results as 135/90 mmHg and above considered hypertensive, lower normotensive. control group included 25 healthy individuals. Serum malondialdehyde (MDA), advanced...

Objective In stored red blood cells (RBCs), which are used in diseases (e.g., acute loss and leukaemia), storage lesions arise by oxidative stress other factors over time. This study investigated the protective effects of resveratrol serotonin on RBCs. Methods Blood from each donor (n = 10) was placed different bags containing 70 mL citrate phosphate dextrose (total volume: 500 mL) divided into three groups 30): control, 60 µg/mL resveratrol, serotonin. Malondialdehyde (MDA) glutathione...

In this study, we investigated the effects of erythropoietin (Epo), and pentoxifylline (Ptx) on oxidant antioxidant systems in experimental short bowel syndrome. Spraque-Dawley rats were divided into four groups all animals underwent 75% small resection. Group E was treated with 500 IU kg(- 1) Epo subcutaneously (s.c.), group P 50 mg day(- s.c. Ptx E+P plus for a period 28 days. C, which is control group, no drug treatment given. At end days experimented killed ileum samples excised...

Behçet's disease (BD) is a chronic inflammatory disorder of unknown aetiology, and recognised as multi-system vasculitis. It has been postulated that an imbalance the oxidant antioxidant systems related to are important in its pathogenesis. Previous publications have reported increased levels enzymatic defence patients with BD. The non-enzymatic systems, including vitamin C uric acid, were looked for present study. For this aim, serum malondialdehyde (MDA), end product lipid peroxidation,...

Objective: To examine serum lipid levels in patients with obsessive–compulsive disorder (OCD) and to test whether panic symptoms affect concentrations OCD patients. Methods: We assessed 33 healthy control subjects matched for sex age. Results: had higher low-density lipoprotein, very-low-density tryglyceride levels, but lower high-density lipoprotein than normal subjects. also found that only attacks concentrations, compared Serum of pure did not differ from values. Conclusion: These...

Abstract We report the concentrations of superoxide dismutase (SOD), glutathione peroxidase (GSH‐Px) and malonaldialdehyde (MDA) an end product lipoperoxidation in human whole blood. Method for measuring was based on spectrophotometer. Blood MDA level higher elderly than children, adults. Smoking, alcohol takiing, acute exercise air pollution group's levels were increased their control groups. GSH‐Px activity significantly lower group, trained group those controls. SOD decreased elderly,...

Hypothyroidism is associated with a number of functional renal disorders primarily affecting water and salt handling. In this study, we aim to investigate in overt subclinical hypothyroidism. We utilised urinary beta-2 microglobulin (beta2M) as sensitive marker tubular dysfunction. Urinary beta2M excretion tests for functions were repeated before after T4 replacement therapy. Forty-four patients (28 disease, 16 disease) 31 healthy control subjects involved the study. There was significant...

Sepsis causes life-threatening tissue and organ dysfunctions caused by endogenous mediators in response to infection. Melatonin is a powerful anti-inflammatory agent effective reducing cellular damage. This study aimed evaluate the changes serum liver levels of VEGF, TGF-β MMP-2 melatonin-treated septic rats.Twenty-one Wistar-albino male rats were included this study. Rats randomly divided into three groups. Group 1 sham-operated control (C) group, 2 caecal ligation puncture (CLP) group 3...

Objectives: Agmatine is a cationic amine resulting from the decarboxylation of l-arginine. has neuroprotective, anti-inflammatory, anti-stress, and anti-depressant properties. In this study, plasma agmatine, arginine decarboxylase, agmatinase levels were measured during manic episode remission period in patients with bipolar disorder. Methods: Thirty healthy volunteers 30 who meet Bipolar Disorder Manic Episode diagnostic criteria included study. Additionally, changes patient group between...