The aim of the present study was to determine serum levels vitamin B12, folate, and homocysteine (Hcy) in mothers their babies, assess association between these neural tube defect (NTD). group included 92 baby-mother pairs, where babies had NTD, control 102 no from May 2012 2015. Plasma Hcy were measured, compared with each other. NTD diagnosed 2.6% our babies. B12 determined as 166.2 ± 63.7 pg/mL 240.3 120.3 pg/mL, 1 9 0 80.2 299.5 151.4 respectively. There a significant difference two...

Protein-energy malnutrition (PEM) results from food insufficiency as well poor social and economic conditions. Development of PEM is due to insufficient nutrition. Children with lose their resistance infections because a disordered immune system. It has been reported that the changes occurring in mediators referred cytokines system may be indicators disorders associated PEM.To determine concentrations pro-inflammatory children PEM, find out whether there was an association clinical...

Aim: Liver and kidney are exposed to a lot of oxidant substances that both from exogen endogen sources. The aim this study was investigate the antioxidant effects C vitamine, Melatonine (MLT) N-acetylcystein (NAC) in carbon tetrachlorur (CCl4) induced oxidative stress mouse. Methods: involved 6 groups; control group (Group 1), CCl4 2), + vitamine 3), MLT 4), NAC 5) combined (CCl4 NAC) 6) with each containing 10 mice. Starting 4th day 0,4 ml/kg were given intraperitoneally (i.p.) all groups...

Venous thromboembolism has multifactorial origin and occurs in the context of complex interactions between environmental genetic predisposing factors. Oxidative stress plays an important role physiopathology venous thrombosis. Current study examined oxidative asymmetric dimethylarginine development DVT with parameters such as serum malondialdehyde (MDA), glutathione peroxidase (GSH-Px), catalase, ADMA, homocysteine, folic acid, vitamin B 6 , 12 levels. Serum MDA levels were found...

It has been reported that many modifications occur with the increase of oxidative stress during storage in erythrocytes. In order to delay these negative changes, we evaluated whether addition substances likely protect antioxidant capacity stored blood would be useful. Therefore, investigated effects resveratrol, tannic acid, and caffeic acid lipid peroxidation erythrocytes blood. Donated was taken into four CPD containing bags. One bag used as control, others were supplemented (30 μ g/mL),...

To compare rectal ibuprofen with oral for the closure of hemodynamically significant patent ductus arteriosus (hsPDA) in very low birth weight (VLBW) preterm infants.In a prospective, randomized study, 72 VLBW infants who had hsPDA received either or ibuprofen. The plasma concentration and renal functions were determined both groups by high-performance liquid chromatography (HPLC) method cystatin-C (cys-C), respectively.The rate group that was similar to (86.1% versus 83.3%) after first...

ObjectivesWarts are abnormal skin growths caused by human papilloma virus (HPV) infections within the of patients. Genital warts usually appear in perianal and perigenital regions. Asymptomatic may be activated after years damage natural immunity. The inflammation that occurs during this process lead to an imbalance between prooxidant antioxidant systems. aim study was investigate erythrocyte glutathione peroxidase (GSH-Px) activity, serum paraoxonase enzyme levels, oxidative stress levels...

Objective In stored red blood cells (RBCs), which are used in diseases (e.g., acute loss and leukaemia), storage lesions arise by oxidative stress other factors over time. This study investigated the protective effects of resveratrol serotonin on RBCs. Methods Blood from each donor (n = 10) was placed different bags containing 70 mL citrate phosphate dextrose (total volume: 500 mL) divided into three groups 30): control, 60 µg/mL resveratrol, serotonin. Malondialdehyde (MDA) glutathione...

The aim of this study was to investigate the effect different doses prednisolone in puppies experimentally induced with meconium aspiration syndrome (MAS). Meconium collected from human babies first day life and released into trachea 11 newborn induce MAS. Puppies were treated 2 mg/kg (standard dose), 30 (megadose) or 0.9% saline, all administered intravenously. ended 20 h after lungs then scored for histopathology. Animals not deteriorated 8 while respiration rate, oxygenation, pH partial...

Stored bloods, are exposed to a number of negative changes called as "storage lesions" morphological, biochemical and functional, begin the first phase storage.In this study, we investigated effects caffeic tannic acid in lipid peroxidation oxidative DNA damage stored blood.The blood was taken from 10 healthy male individuals bag containing CPD.Each donor's separated into three groups.The group used control with nothing added blood.A total 30 µg/mL 15 second third group,...

There exist various harmful substances in cigarette and its smoke. Nicotine, taken as a result of active second hand smoking, turns into “cotinine” with metabolite. Cigarette is known to have toxic effects on peripherical nervous system, cardiovasvcular system endocrin system. Besides, it causes lung, larynx, kidney urinary bladder breast cancer. Some mechanisms been reported cause renal damage. It increases blood pressure leading the activation acute sympatethic formation oxidative stress....

Objective: The study was investigate serum zinc (Zn), chromium (Cr), cobalt (Co) and manganese (Mn) concentrations in relation to hormone levels polycystic ovary syndrome (PCOS).Materials Methods: Fourty women between 18-40 years of age diagnosed with PCOS. We also seleceted 40 healty volunteers as the control group. Serum Zn, Cr, Mn, follicular stimulating (FSH), luteinizing hormone(LH), Dehydroepiandrosterone sulfate (DHEA-S), total testosterone (TT), sex binding globulin (SHBG), insulin,...

This study investigated the relationship between diabetes (DM) and nitrite, nitrate MDA levels effect of melatonin pentoxifylline.Sixty mice were randomly divided into four groups. Control: no action; Diabetes group (DM): after fasting-blood-glucose (FBG) was measured, 150 mg/kg alloxane applied intraperitoneally three-times every other day; + Melatonin (DM MLT) Pentoxifylline groups PTX): following same procedures with DM, 10 50 pentoxifylline administered subcutaneously six days,...

Multiple sclerosis (MS) is a demyelinating disease
 of the nervous system. Evidence about oxidative stress plays an important role
 in pathogenesis MS increasing day by day. In our study, we aimed to
 investigate effect DNA damage and the
 disease. Blood samples were obtained from during attack
 (Group 1), between attacks 2) patients (20 male 10 female) and
 30 healthy volunteers 3). Malondialdehyde (MDA) levels as indicator of
 oxidized lipids detected...

Stored blood for use in diseases such as acute loss, injury and anemia can be maintained about a month.It was reported that some negative changes called "storage lesions" occur stored bloods time dependently.In order to delay these changes, preservatives are added bloods.In this study, we aimed determine the effects of resveratrol serotonin on oxidative DNA mitochondrial damage lipid peroxidation blood.Blood taken from 10 volunteers different bags each separated into 3 groups (control,...

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folat, methionine and homocysteine metabolism. In this study, our objective to investigate the genotype allele distributions of MTHFR C677T A1298C gene polymorphisms patients with Cerebrovascular disease, Coagulation disorder those pre-diagnosed Hypertension Van province its environments. The results analyses 109 were evaluated retrospectively. These divided into three groups as disorder. analysis, CVD T (Cardiovascular Disease...