A5046431144- Coenzyme Q10 studies and effects
- Adipose Tissue and Metabolism
- Obstructive Sleep Apnea Research
- Asthma and respiratory diseases
- Genomics, phytochemicals, and oxidative stress
- Nitric Oxide and Endothelin Effects
- Free Radicals and Antioxidants
- Metabolomics and Mass Spectrometry Studies
- Advanced battery technologies research
- Dental materials and restorations
- Oral microbiology and periodontitis research
- Antioxidant Activity and Oxidative Stress
- Tryptophan and brain disorders
- Biochemical effects in animals
- Dental Erosion and Treatment
- Cardiovascular Health and Disease Prevention
- Vitamin D Research Studies
- Neuroscience and Neuropharmacology Research
- Advanced Glycation End Products research
- Nigella sativa pharmacological applications
- Paraoxonase enzyme and polymorphisms
- Cancer, Stress, Anesthesia, and Immune Response
- Vitamin C and Antioxidants Research
- Cancer, Hypoxia, and Metabolism
- Dialysis and Renal Disease Management
Van Yüzüncü Yıl Üniversitesi
2016-2025
Hefei University of Technology
2024
Weatherford College
2023
Kahramanmaraş Sütçü İmam University
2022
Apple (United States)
2021
Eskişehir Osmangazi University
2021
Atatürk University
2008-2016
Creative Commons
2015
Bursa Uludağ Üni̇versi̇tesi̇
2012
Erciyes University
2012
Although many drugs are available for the treatment of gastric ulcers, often these ineffective. Many antidepressant have been shown to antiulcer activity in various models experimental ulcer. One such drug, mirtazapine, has reported an effect that involves increase antioxidant, and a decrease oxidant, parameters. To date, however, there is no information regarding similar antidepressant, fluvoxamine. This study aimed investigate effects fluvoxamine determine its relationship with...
Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by repetitive thoughts and behaviors. The kynurenine pathway has been increasingly implicated in disorders. This study aimed to investigate the predictive value of metabolites, including serotonin tryptophan, patients with varying degrees OCD. One hundred fifty OCD 30 healthy controls were included this study. Patients divided into mild-moderate, severe, extremely severe groups based on their Yale-Brown...
Abstract Amongst the main perspectives when evaluating results of medical studies are statistical significance (following formal testing) and clinical significance. While shows that a factor’s observed effect on study is unlikely (for given alpha) to be due chance, size substantial enough clinically useful. The essence “negative” - factor under probably did not happen by chance. In contrast, evaluate whether “positive” effective cost-effective. Medical diagnoses treatments should never based...
Age-related macular degeneration (AMD) is one of the most common causes vision loss. AMD has been classified into two forms: atrophic and exudative forms. The form associated with choroidal neovascularization subretinal region, resulting in a sudden loss central vision. However, exact cause remains unknown. Several risk factors have postulated, including smoking, atherosclerosis, low levels antioxidant enzymes. Malondialdehyde (MDA), lipid peroxidation product, used as marker oxidative...
The correlation of coronary artery disease (CAD) with pro-oxidant/antioxidant balance and oxidative DNA damage was investigated. Seventy-seven patients CAD 44 healthy individuals as control were included in this study. comparative ratios ubiquinol-10/ubiquinone-10, 8-hydroxy-2(')-deoxyguanosine/deoxyguanosine the level MDA measured by HPLC activities GPX SOD colorimetric approach blood samples obtained from unraveled.8-OHdG/dG ratios, serum activity found significantly elevated compared to...
Oxidative damage is a major contributing factor to carcinogenesis and obstructive disorders in lungs. Current evidence suggests that the inflammatory processes yield oxidative mechanisms, which underlie COPD, lung cancer, sleep apnea syndrome (OSAS). This study aimed evaluate these diseases by evaluating antioxidant biomarkers.Malondialdehyde, 8-oxo-7,8-dihydro-2'-deoxyguanosine, coenzyme Q10 levels were evaluated blood samples of subjects with OSAS high-pressure liquid chromatography.A...
To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.Patients with type 2 diabetes PDRP were determined to be case group (n=50). The control was consist of healthy individuals Plasma CoQ10 malondialdehyde (MDA) levels measured in both groups.Ubiquinone-10 (Coenzyme Q10) subjects are 3.81±1.19µmol/L 1.91±0.62µmol/L, respectively. MDA 8.16±2µmol/L 3.44±2.08µmol/L, Ratio Ubiquinol-10/ubiquinone-10 0.26±0.16 1.41±0.68,...
Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). The aim this study was to evaluate relationship between oxidative DNA damage [8-hydroxy-2′-deoxyguanosine/deoxyguanosine ratio (8-OHdG/dG ratio)], stress biomarkers and endothelial function HD as an indicator atherosclerosis. Forty-four without known atherosclerotic disease 55 age- sex-matched healthy individuals were included study. Plasma malondialdehyde (MDA) levels 8-OHdG/dG determined...
Abstract Objectives This study aimed to objectively assess the potential severity of harm associated with erroneous results in 195 laboratory tests by surveying 514 specialist physicians and medical biochemistry experts. Methods The survey obtained participants’ (75 biochemists, 439 clinicians) opinions on for tests. comprehensive list errors their effects test were from literature, then matched scores, 1 (negligible effect) 5 (life-threatening injury/death), responses. Results Participants...
Acta Ophthalmol. 2010: 88: 891–895 Abstract. Purpose: This study examines the levels of oxidative damage in patients with cataract. Methods: Blood samples were collected from 60 cataract and age‐ gender‐matched healthy individuals to measure 8‐hydroxy 2‐deoxyguanosine (8‐OHdG) malondialdehyde (MDA) levels. Results: A significant difference was observed leukocyte 8‐OHdG comparison persons (p < 0.001). Similarly, a plasma MDA In addition, correlation found between DNA ( r = 0.859, p...
Abstract The effects of vitamin E and Hippophea rhamnoides L. extract (HRe‐1) on nicotine‐induced oxidative stress in rat heart were investigated. There eight rats per group supplementation period was 3 weeks. groups were: nicotine [0.5 mg kg −1 day , intraperitoneal (i.p.)]; plus [75 intragastric (i.g.)]; HRe‐1 (250 i.g.); the control (receiving only vehicles). Nicotine increased malondialdehyde level, which prevented by both HRe‐1. Glutathione peroxidase (GPx) activity supplemented higher...
Abstract Oxidative stress is accepted as a nonclassical cardiovascular risk factor in chronic renal failure patients. The aim of this study was to evaluate the relation between oxidative DNA damage (8‐hydroxy‐2′‐deoxyguanosine/deoxyguanosine [8‐ OHdG / dG ] ratio), biomarkers, antioxidant enzymes, and carotid artery intima‐media thickness ( CIMT ) hemodialysis HD Forty patients without known atherosclerotic disease 48 age‐ sex‐matched healthy individuals were included study. Plasma...
This study examines the levels of oxidative damage in patients with retinopathy prematurity (ROP).Fifty were recruited a birthweight below 1500 g or gestational age 32 weeks. The cases classified into those who developed ROP (n=25) and without (n=25). authors obtained blood urine samples from each infant, for measuring 8-hydroxy 2-deoxyguanosine (8-OHdG) malondialdehyde (MDA) levels, at time first examination 4-6 postnatal weeks.A significant difference was observed leukocyte 8-OHdG compared...
Aim: There is much evidence of an association between cancer and irisin that adipokine. This study researched on the relationship prostate (PCa) levels, whether can be used as a biomarker in diagnosis PCa. Materials Methods: For groups, 50 primary PCa patients 30 healthy male subjects were included control respectively. All volunteers group screened for other malignancies chronic diseases. Volunteers who determine to completely group. In serum samples measured free PSA, total PSA levels....
The aim of this study was to evaluate the role α-lipoic acid (α-LA) on oxidative damage and inflammation that occur in endothelium aorta heart while constant consumption high-fructose corn syrup (HFCS). rats were randomly divided into three groups with each group containing eight rats. include HFCS, HFCS + α-LA treatment, control. given at a ratio 30% F30 drinking water for 10 weeks. treatment dose 100 mg/kg/day orally last 6 At end experiment, killed by cervical dislocation. blood samples...
Osteoporosis is a major public health problem associated with many factors, and it affects more than 50% of women over 50 years old. In the current study, our purpose was to investigate effects phosphodiestarase-5 inhibitors on osteoporosis via nitric oxide/3′,5′-cyclic guanosine monophosphate/protein kinase G signalling pathway. A total female albino Wistar rats were separated into five groups. The first group appointed as healthy control no ovariectomy. All animals in other groups...