Aim: We investigated the association of mean platelet volume (MPV) with degree retinopathy in patients diabetes mellitus (DM). Methods: Ninety diabetic (DRP) and 30 healthy individuals were included study. Diabetic background, non-proliferative proliferative cases. Complete blood count, intra- intergroup comparisons MPV values performed. Results: Mean for nonproliferative DRP 7.76±0.72 fL, 7.94±0.61 fL 8.18±0.89 respectively. background was not significantly different from that control group...

Age-related macular degeneration (AMD) is one of the most common causes vision loss. AMD has been classified into two forms: atrophic and exudative forms. The form associated with choroidal neovascularization subretinal region, resulting in a sudden loss central vision. However, exact cause remains unknown. Several risk factors have postulated, including smoking, atherosclerosis, low levels antioxidant enzymes. Malondialdehyde (MDA), lipid peroxidation product, used as marker oxidative...

To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.Patients with type 2 diabetes PDRP were determined to be case group (n=50). The control was consist of healthy individuals Plasma CoQ10 malondialdehyde (MDA) levels measured in both groups.Ubiquinone-10 (Coenzyme Q10) subjects are 3.81±1.19µmol/L 1.91±0.62µmol/L, respectively. MDA 8.16±2µmol/L 3.44±2.08µmol/L, Ratio Ubiquinol-10/ubiquinone-10 0.26±0.16 1.41±0.68,...

Acta Ophthalmol. 2010: 88: 891–895 Abstract. Purpose: This study examines the levels of oxidative damage in patients with cataract. Methods: Blood samples were collected from 60 cataract and age‐ gender‐matched healthy individuals to measure 8‐hydroxy 2‐deoxyguanosine (8‐OHdG) malondialdehyde (MDA) levels. Results: A significant difference was observed leukocyte 8‐OHdG comparison persons (p < 0.001). Similarly, a plasma MDA In addition, correlation found between DNA ( r = 0.859, p...

To evaluate the efficacy of topical N-acetyl-cysteine (NAC) therapy in patients with meibomian gland dysfunction (MGD).Twenty MGD were prospectively randomized and assigned into 2 groups. The instructed to use either NAC 5% or preservative-free artificial tear topically 4 times a day for month. All apply lid hygiene once daily. Preservative-free tears treated group served as control. Paired sample Student's t-tests used detect differences between baseline 1 month after treatment initiation...

MMP-9 plays a prominent role in inflammation and MMP-14 take part angiogenesis. The objective of this study is to compare levels between diabetic non-diabetic patients.The patients who scheduled for pars plana vitrectomy were included our study. Patients are divided into 2 groups: the group group. Age, gender, intraocular pressure(IOP), visual acuity (VA) reported. Color fundus photography, fluorescein angiography, optic coherence tomography (OCT) performed before after operation. vitreous...

To compare the anti-inflammatory and analgesic effects of topical pranoprofen 0.1% with diclofenac sodium after strabismus surgery, 40 patients were prospectively randomized assigned into 2 groups. Signs symptoms inflammation, as well intraocular pressure (IOP) patients, evaluated at 1 day 3 weeks following surgery. Both groups reported reduced inflammation discomfort week, compared to day. There was no statistically significant difference in any measurement postoperative (i.e., discomfort,...

This study examines the levels of oxidative damage in patients with retinopathy prematurity (ROP).Fifty were recruited a birthweight below 1500 g or gestational age 32 weeks. The cases classified into those who developed ROP (n=25) and without (n=25). authors obtained blood urine samples from each infant, for measuring 8-hydroxy 2-deoxyguanosine (8-OHdG) malondialdehyde (MDA) levels, at time first examination 4-6 postnatal weeks.A significant difference was observed leukocyte 8-OHdG compared...

Abstract Background The pterygopalatine ganglion (PPG) and ophthalmic arteries (OpAs) have important roles in ocular autoregulation retinal visual functions. relationship between PPG neuron density, OpA vasospasm, detachment subarachnoid hemorrhage (SAH) has never been studied. Methods This study was conducted on 25 rabbits. Five animals were the control group (GI; n = 5), five sham (GII; 15 (GIII; 15). After injection of 1 cc serum saline into cisterna magna group, autologous blood SAH...

This study aimed to compare the efficacy of topical N-acetyl-cysteine (NAC) with a steroid-antibiotic combination, betamethasone-sulfacetamide sodium therapy in patients meibomian gland dysfunction (MGD).Twenty MGD were prospectively randomized and assigned into 2 groups. The instructed use either NAC 5% or betamethasone 0.1%-sulfacetamide 10%, topically 4 times day for month. All apply lid hygiene once daily.One month provided statistically significant improvements fluorescein break-up time...

Background and Study Aim Basic neurophysiologic principles of the light reflex are well known. However, effects degenerated axon densities oculomotor nerves (OMNs) secondary to posterior communicating artery (PComA) vasospasm following subarachnoid hemorrhage (SAH) have not been investigated. Our aim was study this subject. Methods This conducted on 19 rabbits. There a control group five animals, sham animals in which saline injected into cisterna magna nine homologous blood magna. Pupillary...

Background:The aim of this study is to describe the type and severity paintball-related ocular trauma determine necessary precautions minimize risk injury regardless whether adequate eye protection was used. Material andMethods:A retrospective chart review identified patients treated for at Ataturk University Medical Hospital from June 2010 through March 2013. A descriptive analysis data performed. Results:Ten with were identified. At time their first examination, 7 these had visual acuity...

The aim of this study was to investigate central anti-nociceptive mechanisms i.v. acetylsalicylic acid (ASA) and oral zolmitriptan (ZOL) in migraine patients healthy subjects using the ‘nociceptive’ blink reflex (nBR). Twenty-eight received ASA ( n = 14, 1000 mg i.v) or ZOL 5 p.o) during acute attack interictally. Thirty either vs. placebo a double blind cross over design. nBR recorded all before, 60 90 min after treatment. did not inhibit responses subjects. Both suppressed (ASA by 68%,...

Increased oxidative stress might play an important role in the initiation and progression of diabetic complications. The present study has been undertaken to investigate whether there is any relationship between retinopathy degree leukocyte superoxide dismutase (SOD) catalase (CAT) activities lipid peroxidation (LPO) individuals with type 2 retinopathy. Patients were groupped respect Leukocyte malondialdehyde (MDA) levels, SOD CAT measured patients diabetes mellitus (n=41) nondiabetic...

The aim was to evaluate central corneal thickness in patients with meibomian gland dysfunction.The study group made up of 40 eyes 20 dysfunction (mean age, 40.55 ± 10.7 years). Forty healthy individuals 39.25 11.1 years) without any ophthalmic or systemic pathology were used as a control group. measured ultrasonic pachymetry.The mean 541.45 24.68 µm the and 544.30 22.16 There no statistically significant difference measurements comparison (p > 0.05).Central do not differ compared subjects.

Since the free amino acids (a.a.) and derivated a.a. compounds in physiological fluids might reflect or pathological conditions, some researchers have investigated correlation of concentrations with clinical including ocular diseases. Here, we aimed to compare nuclear (generally a physiologic condition) cortical pathologic cataract. Materials methods: Ten patients 10 cataract were included this study. Aqueous humour determined by HPLC method (HP 1100) Pickering post-column derivatization....

To investigate the relationship between neuron density of superior cervical sympathetic ganglia and pupil diameter in subarachnoid hemorrhage.This study was conducted on 22 rabbits; 5 for baseline control group, SHAM group 12 group. Pupil diameters were measured via sunlight ocular tomography day 1 as values. re-measured after injecting 0.5 cc saline to autologous arterial blood into cisterna magna After 3 weeks, brain, ciliary extracted with peripheral tissues bilaterally examined...

The aim f this study was to evaluate the effect of capsular tension ring implantation during cataract surgery on incidence neodymium: YAG (Nd: YAG) laser posterior capsulotomy in myopic (axial length [AL] ≥25.00 mm) eyes. MATERIAL/METHODS In retrospective study, records cases 117 patients who underwent between January 2004 and 2011 were reviewed. A total 153 eyes with an axial 25 mm or higher included consideration exclusion criteria mentioned below. Eyes grouped by presence lack (CTR+ CTR-,...

Although it is well known that meningitis frequently results in optic nerve (ON) and oculomotor (OMN) dysfunctions, the effects of on ciliary ganglion (CG) have not been studied. It expected CG may be affected due to involvement these cranial nerves meningitis. In this study, we aimed investigate effect CG.This study was conducted thirteen rabbits. Experimental has achieved with Streptococcus pneumonias inoculation into cisterna magna animals. After follow-up two months, all animals were...

Abstract A case with pulmonary atresia/ventricular septal defect associated port‐wine stain and retinal vascular abnormality is reported. Clinical findings were similar to both PHACE syndrome Sturge–Weber (SWS). But, the most frequent well‐known features of syndromes absent. So, it could not be concluded whether this a new constellation or an incomplete form one two syndromes. In situations, presence complex congenital heart disease that has been reported previously makes original. © 2003...