A5102853730- Folate and B Vitamins Research
- Inflammasome and immune disorders
- Cardiac Ischemia and Reperfusion
- Dialysis and Renal Disease Management
- Trace Elements in Health
- Environmental Toxicology and Ecotoxicology
- Multiple Sclerosis Research Studies
- Kidney Stones and Urolithiasis Treatments
- Paraoxonase enzyme and polymorphisms
- Heart Failure Treatment and Management
- Free Radicals and Antioxidants
- Vitamin C and Antioxidants Research
- Family Caregiving in Mental Illness
- Bioactive Compounds and Antitumor Agents
- Nigella sativa pharmacological applications
- Organ Donation and Transplantation
- Pesticide Exposure and Toxicity
- Aluminum toxicity and tolerance in plants and animals
- Plant Micronutrient Interactions and Effects
- Neurological Complications and Syndromes
- Ocular Diseases and Behçet’s Syndrome
- Birth, Development, and Health
- Hormonal Regulation and Hypertension
- Cardiac and Coronary Surgery Techniques
- Connexins and lens biology
Atatürk University
2011-2022
Üsküdar University
2022
Mevlana University
2015
University of Benin
2013
Czech Academy of Sciences, Institute of Physiology
2012
Scientific and Technological Research Council of Turkey
2012
Erzurum Technical University
2011
Multiple sclerosis (MS) is a disease characterised by perivascular infiltrates and demyelination of the white matter in central nervous system. Although precise cause MS remains unknown, some investigations have been carried out on antioxidant mechanisms these patients.In this study, malondialdehyde (MDA), as lipid peroxidation marker, ceruloplasmin (Cp) transferrin (Trf), proteins, levels were determined cerebrospinal fluid (CSF) serum 30 patients before after corticosteroid therapy 20...
Peripheral blood cultures were exposed to various doses (5 500 mg/L) of boron compounds. Sister-chromatid exchange, micronucleus and chromosomal aberration tests applied estimate the DNA damage, biochemical parameters (superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase, glucose-6-phosphate dehydrogenase, total glutathione, malondialdehyde antioxidant capacity) examined determine oxidative stress. According our findings, compounds at low useful in supporting...
Context Nigella sativa L. (Ranunculaceae) (NS) is traditionally used to treat many conditions such as inflammation. Objective This study evaluates the effects of NS seeds ethanol extract in paracetamol-induced acute nephrotoxicity rats. Materials and methods Forty-eight female Wistar Albino rats were divided into eight groups: I = sham; II sham + 1000 mg/kg NS; III 140 (N-acetyl cysteine) NAC; IV 2 g/kg paracetamol; V paracetamol VI, VII VIII 250, 500 NS, respectively. Paracetamol...
Pesticide toxicities are common in aquatic ecosystems and affects livings negative. Therefore, it is important to strengthen the antioxidant system organisms protect against these toxic chemicals. In this study, simulative toxicity was established fish then healing process followed. For purpose, rainbow trout Oncorhynchus mykiss exposed cypermethrin left recovery with either N-acetyl cysteine (an antioxidant, 0.5 mM–1.0 mM concentrations) or no intervention (self-healing) for 96 h. context,...
The aim of this study was to determine the effects Hippophae rhamnoides L. extract (HRe-1) and also vitamin E as a positive control on nicotine-induced oxidative stress in rat blood, specifically alterations erythrocyte malondialdehyde (MDA) level, activities some antioxidant enzymes, plasma A levels. groups were: nicotine (0.5 mg/kg/d, intraperitoneal, i.p.); nicotine+vitamin (75 intragastric, i.g.); nicotine+HRe-1 (1 ml/kg/d, group (receiving only vehicles). There were 8 rats per...
Introduction: Behçet’s disease (BD) is a chronic systemic disorder characterised by oral and genital ulcerative lesions, ocular cutaneous manifestations. Cytokines are the major mediators of immunologic inflammatory reactions. Nitric oxide reactive nitrogen intermediate which plays key role in pathogenesis many autoimmune skin diseases. The study was conducted to determine serum interleukin-2 (IL-2), interleukin-6 (IL-6), tumour necrosis factor (TNF)-alpha nitric levels relation disease....
Genetic, neuropathological and biochemical investigations have revealed meaningful relationships between aluminum (Al) exposure neurotoxic hematotoxic damage. Hence, intensive efforts are being made to minimize the harmful effects of Al. Moreover, boron compounds used in a broad mix industries, from cosmetics pharmaceuticals agriculture. They affect critical biological functions cellular events enzymatic reactions, as well endocrinal mineral metabolisms. There limited dose-related data about...
To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration.Patients with type 2 diabetes PDRP were determined to be case group (n=50). The control was consist of healthy individuals Plasma CoQ10 malondialdehyde (MDA) levels measured in both groups.Ubiquinone-10 (Coenzyme Q10) subjects are 3.81±1.19µmol/L 1.91±0.62µmol/L, respectively. MDA 8.16±2µmol/L 3.44±2.08µmol/L, Ratio Ubiquinol-10/ubiquinone-10 0.26±0.16 1.41±0.68,...
Carvone (CVN) is a monocyclic monoterpene found in the essential oils of Mentha spicata var. crispa (Lamiaceae) and Carum carvi L. (Apiaceae) plants has been reported to have antioxidant, antimicrobial, anticonvulsant, antitumor activities. The beneficial health properties CVN encouraged us look into its anticancer activity. To best our knowledge, reports are not available on activity cultured primary rat neuron N2a neuroblastoma (NB) cells. Therefore, present study an attempt toward...
The aim of this study was to evaluate the effects aliskiren, direct renin inhibitor, as an antioxidant and tissue protective agent molecular, biochemical, histopathological changes in experimental ischemia ischemia/reperfusion injury rat ovaries. Forty-eight female rats were randomly divided into eight groups: Group 1, only sham operation performed. 2 received 100 mg/kg aliskiren operated. In 3, 3 h-period bilateral ovarian applied. 4 a 3-h period followed by h reperfusion. Groups 5 6 50...
To evaluate biochemically and histopathologically the effects of Nigella sativa (NS) in experimental ischemia ischemia/reperfusion (I/R) injury rat ovaries.Thirty-six female rats were divided into 6 groups: group I = sham operation; II 500 mg/kg NS + III bilateral ovarian ischemia; IV V 3-hour period reperfusion, VI: 2.5 h after induction reperfusion. At end ischemia, vascular clips removed, reperfusion was continued. IL-1β, IL-6, TNF-α cytokine levels serum, superoxide dismutase (SOD),...
Objectives: The aim of the present study was to evaluate osseous changes jaws patients with chronic renal failure (CRF) by CBCT. Methods: On CBCT scans obtained from 15 CRF and control (7 males 8 females), mean calculated for antegonial index (AI), mental (MI), panoramic mandibular (PMI) cortical (MCI). MI, AI PMI, pulp chamber size, number teeth calcification lamina dura loss were compared using paired t-test, MCI values analysed χ2 test. Results: There no statistically significant...