A5077918524- Endometriosis Research and Treatment
- Bacterial Infections and Vaccines
- Metabolomics and Mass Spectrometry Studies
- Sexual function and dysfunction studies
- Parathyroid Disorders and Treatments
- Metabolism and Genetic Disorders
- Vector-Borne Animal Diseases
- Stress Responses and Cortisol
- Vitamin D Research Studies
- Biomarkers in Disease Mechanisms
- Viral Infections and Outbreaks Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Pneumonia and Respiratory Infections
- Viral Infections and Vectors
- Bone health and osteoporosis research
- Immune Response and Inflammation
- Hormonal Regulation and Hypertension
- Birth, Development, and Health
- S100 Proteins and Annexins
- Cancer, Stress, Anesthesia, and Immune Response
- Orthopedic Infections and Treatments
- Diabetes and associated disorders
- Apelin-related biomedical research
- Renal function and acid-base balance
Van Yüzüncü Yıl Üniversitesi
2020-2025
Weatherford College
2023
Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by repetitive thoughts and behaviors. The kynurenine pathway has been increasingly implicated in disorders. This study aimed to investigate the predictive value of metabolites, including serotonin tryptophan, patients with varying degrees OCD. One hundred fifty OCD 30 healthy controls were included this study. Patients divided into mild-moderate, severe, extremely severe groups based on their Yale-Brown...
Aim: It was aimed to evaluate the diagnostic performance of hemoglobin A1c (HbA1c) test in pediatric prediabetes, and determine cut-off value for adolescent. 
 Material Method: This study carried out by retrospectively evaluating data 379 adolescents aged between 10 18 years. Prediabetes diagnosed based on glucose criteria, either fasting or 2-hour (2h) during a 75 g oral tolerance (OGTT), HbA1c criteria. The sensitivity, specificity, positive predictive (PPV), negative (NPV) were...
This study investigated effects of zaprinast and avanafil on angiogenesis, vascular endothelial growth factor (VEGF), bone morphogenic protein (BMP) 2, 4 7.Female rats were randomly divided into four groups (n = 6). Sham; abdomen was approximately 2 cm opened closed. Ovariectomised (OVX); the ovaries cut. OVX + groups; after same procedure with OVX, 10 mg/kg orally administered for month, respectively. Angiogenesis levels VEGF, BMP2, 7 determined.VEGF, in especially higher than sham (p <...
Objective: This study investigated effect of zaprinast and avanafil on vascular endothelial growth factor (VEGF), bone morphogenic protein (BMP) 4 7, vitamin D3 levels against the negative dexamethazone.Method: Rats were randomly divided into four groups (n = 6). Control: Empty a syringe was immersed removed subcutaneously. Dexamethasone (DEX): 120 µg/kg DEX injected subcutaneously once day for 28 days. + groups: 10 mg/kg administrated to rats in addition same procedure DEX, respectively....
The aim of this study was to evaluate mitofusin-2 levels and fetal Doppler ultrasonography effects in patients with severe preeclampsia.
In our study, we aimed to detect amino acid changes, if any, by comparing the levels of acids in cerebrospinal fluid (CSF) samples patients with aseptic, bacterial, and tuberculous meningitis control groups.Patients diagnosed aseptic (n=41), meningi tis (n=21), bacterial (n=41) a group consisting 64 individuals similar gender age characteristics were included study.2 mL specimens obtained from all sto red at -80 °C until study day.The measurements performed using commercially available...
The aim of this study was to determine how the levels peptide and protein-based biomarkers in cerebrospinal fluid change bacterial, tuberculous, aseptic meningitis, success these agents distinguishing between different types infectious meningitis.The arachidonate-5-lipoxygenase, S100 calcium-binding protein B, defensin-α 1, glial fibrillary acidic samples from 20 tuberculosis, 40 25 meningitis patients, 55 control groups were measured compared using an enzyme-linked immunosorbent assay.The...
Studies reported that phosphodiesterase-5 inhibitors (PDE-5Is) positively contributed to bone-mineral-density and thickness in rats with ovariectomy, which have the same condition postmenapozal period.To explain positive contribution mechanism on bone mineral density of PDE-5Is, we investigated effect zaprinast avanafil levels some pro -or anti-resorptive cytokines ovariectomized-rats.Albino female (8 months 250-350 g) were used four groups equal-number randomly assigned (n=6).Groups; was...
Amaç: Kırım Kongo Kanamalı Ateşi (KKKA), sıklıkla kene tutunması ile bulaşan, ateş, myalji ve kanamalar seyreden zoonotik bir hastalık olup önemli halk sağlığı sorunlarına yol açabilmektedir. Klinik belirtiler epidemiyolojik öykü yanında, kan sayımı biyokimyasal test sonuçları KKKA için ilk ipuçlarını oluşturmaktadır. Bu çalışmada hastanemizde tanısı takip tedavi edilen 13 olgunun retrospektif olarak değerlendirilmesi amaçlanmıştır. 
 Materyal Metot: Kliniğimizde 2019-2022 yılları...
Introduction:Osteoporosis is an important health problem and there no effective treatment yet.phosphodiesterase 5 inhibitors are promising agents for the of osteoporosis.In this study, we aimed to determine effects phosphodiesterase (vardenafil, tadalafil, udenafil) on bone morphogenic protein-2 9 (BMP-2 9), vascular endothelial growth factor (VEGF), oxidative stress markers (malondialdehyde CoQ10) in liver tissue rats with ovariectomy-induced osteoporosis.Materials Methods: 50 Albino wistar...
Abstract Background Urine amino acid analysis is used for the assessment of various diseases. The aim this study was to estimate valid biological variation (BV) components (within- and between-subjects) required safe clinical application free urine acids. Methods First morning void samples were taken from 12 healthy subjects (five females, seven males) once a week 10 consecutive weeks, performed using an Agilent 6470 triple quadrupole tandem mass spectrometer instrument. obtained data...
Amaç:
It has been reported that carnitine deficiency is observed in various viral infections and the follow-up of prognosis some diseases. In this cross-sectional study, we aimed to determine how ester derivatives change HIV-positive patients.In 25 HIV-infected patients who applied Harran University Faculty Medicine Education Research Practice Hospital Infectious Diseases Clinical Microbiology Outpatient Clinic did not receive any antiretroviral treatment, as well healthy volunteers were included...
Aim: The aim was to evaluate the diagnostic performance of corrected calcium formulas in diagnosis hypocalcemia.
 Materials and Methods: Corrected levels were calculated using Modified Orrell, Payne, Berry James methods. Individuals divided into groups according albumin levels. In each hypoalbuminemia normoalbuminemia groups, values measured serum total calcium, concentration hypocalcemia calculated. diagnosed by free levels
 Results: 46.3% results group 53.7% group. test with...