Serkan Bolat

ORCID: 0000-0002-8669-8782
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About
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Research Areas
  • Lipoproteins and Cardiovascular Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Viral Infections and Vectors
  • COVID-19 Clinical Research Studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Bacillus and Francisella bacterial research
  • Yersinia bacterium, plague, ectoparasites research
  • Fire effects on ecosystems
  • Long-Term Effects of COVID-19
  • Nuclear Issues and Defense
  • Mosquito-borne diseases and control
  • Clinical Laboratory Practices and Quality Control
  • Coronary Interventions and Diagnostics
  • Vector-Borne Animal Diseases
  • Sleep and Wakefulness Research
  • Research in Cotton Cultivation
  • Brain Metastases and Treatment
  • Nuclear Structure and Function
  • COVID-19 and Mental Health
  • Vitamin C and Antioxidants Research
  • Potassium and Related Disorders
  • Muscle and Compartmental Disorders
  • Viral Infections and Outbreaks Research
  • Cardiac Valve Diseases and Treatments
  • scientometrics and bibliometrics research

Sivas Cumhuriyet Üniversitesi
2020-2025

Ministry of Health
2016

University of Lübeck
2011

Medizinische Hochschule Hannover
2005

Abstract Coronavirus disease 2019 (COVID‐19) is an infectious respiratory caused by a new strain of the coronavirus. There limited data on pathogenesis and cellular responses COVID‐19. In this study, we aimed to determine variation metabolites between healthy control COVID‐19 via untargeted metabolomics method. Serum samples were obtained from 44 patients 41 controls. Untargeted analyses performed LC/Q‐TOF/MS (liquid chromatography quadrupole time‐of‐flight mass spectrometry) Data...

10.1002/jmv.26716 article EN Journal of Medical Virology 2020-12-10

Background Low-density lipoprotein cholesterol (LDL-C) is an important biomarker for determining cardiovascular risk and regulating lipid lowering therapy. Therefore, the accurate estimation of LDL-C concentration essential in disease diagnosis prognosis. Sampson recently proposed a new formula LDL-C. However, little known regarding validation this formula. Objectives This study aimed to validate with other well-known formulas Turkish population, composed adults. Methods A total 88,943...

10.1371/journal.pone.0263860 article EN cc-by PLoS ONE 2022-05-13

Abstract Objectives This study aimed to objectively assess the potential severity of harm associated with erroneous results in 195 laboratory tests by surveying 514 specialist physicians and medical biochemistry experts. Methods The survey obtained participants’ (75 biochemists, 439 clinicians) opinions on for tests. comprehensive list errors their effects test were from literature, then matched scores, 1 (negligible effect) 5 (life-threatening injury/death), responses. Results Participants...

10.1093/ajcp/aqae144 article EN American Journal of Clinical Pathology 2024-10-22

This study aimed to investigate the effects of lipemia on clinical chemistry and coagulation parameters in native ultralipemic (NULM) intravenous lipid emulsion (IVLE) spiked samples.

10.11613/bm.2024.020701 article EN cc-by Biochemia Medica 2024-04-16

Crimean-Congo Hemorrhagic Fever (CCHF) presents a spectrum of clinical manifestations, ranging from asymptomatic cases to severe, life-threatening conditions. Despite extensive research on CCHF pathogenesis, comprehensive understanding remains elusive. Our investigation focused assessing serum beta 2-microglobulin (β2M) levels in patients, aiming elucidate its potential as an immune activation marker and involvement disease pathogenesis. The study enrolled 45 patients healthy volunteers...

10.17776/csj.1422543 article EN Cumhuriyet Science Journal 2024-06-29

Abstract Objectives It is vital to determine the intensive care unit (ICU) requirement at an early stage reduce mortality rate in COVID-19 patients. The aim of study was find reliable predictive markers ICU requirement. Methods We retrospectively reviewed clinical and laboratory records 151 abilities biochemical parameters computed tomography (CT) score were evaluated Results area under curve (AUC) values for procalcitonin, D-Dimer, C reactive protein (CRP), glucose, lactate dehydrogenase...

10.1515/tjb-2020-0359 article EN cc-by Turkish Journal of Biochemistry 2021-02-03

Low-density lipoprotein cholesterol (LDL-C) is a well-established biomarker in the management of dyslipidemia. Therefore, we aimed to evaluate concordance LDL-C-estimating equations with direct enzymatic measurement diabetic and prediabetic populations. The data 31,031 subjects included study were divided into prediabetic, diabetic, control groups according HbA1c values. LDL-C was measured by homogenous assay calculated Martin-Hopkins, Martin-Hopkins extended, Friedewald, Sampson equations....

10.3390/jcm12103570 article EN Journal of Clinical Medicine 2023-05-20

ABSTRACT Purpose Adipose tissue has an important endocrine function by secreting a variety of hormones known as adipokines, such Visfatin, Omentin‐1 and Chemerin. On the other hand, these are also secreted from places than fatty tissues in girl's genital system. The goal this study was to demonstrate secretory status adipokines patients with central precocious puberty (CPP) their utility diagnosis puberty. Method A total 105 were included (53 CPP group 52 control group). following used...

10.1111/cen.15132 article EN Clinical Endocrinology 2024-09-16

OBJECTIVES: In this study, it was aimed to investigate whether or not platelet-rich plasma (PRP) causes intraabdominal adhesions and therefore, PRP can be used safely in intra-abdominal operations.METHODS: Of the total of 35 animals, 5 were as donors for preparation (PRP).The surgical procedures performed on remaining 30 animals.These rats randomized divided into 3 groups 10.In Group 1, no adhesion induction performed.Adhesion induced by cecal abrasion peritoneal resection model Groups II...

10.4149/bll_2016_102 article EN Bratislavské lekárske listy/Bratislava medical journal 2016-01-01

Crimean-Congo hemorrhagic fever (CCHF) is an emerging acute viral infection disease, yet its pathophysiology remains largely uncharacterized. Lipid mediators are molecules that play numerous roles in the physiologic and pathophysiologic conditions certain diseases. No previous study evaluated status of cysteinyl leukotrienes (CYSLT) 5-lipoxygenase (5-LO) their relationship with proinflammatory cytokines CCHF. A total 90 subjects including 60 CCHF patients 30 healthy controls were enrolled...

10.1002/jmv.28199 article EN Journal of Medical Virology 2022-10-08

Abstract Background Low-density lipoprotein cholesterol (LDL-C) is an important biomarker for determining cardiovascular risk and regulating lipid lowering therapy. Therefore, the accurate estimation of LDL-C concentration essential in disease diagnosis prognosis. Sampson recently proposed a new formula LDL-C. However, little known regarding validation this formula. Objectives This study aimed to validate with other well-known formulas Turkish population, composed adults. Methods A total...

10.1101/2022.01.29.22270067 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2022-01-30

Several studies have shown a high prevalence of dyslipidemia in children. Since childhood lipid concentrations continue into adulthood, recognition abnormalities the early period is crucial to prevent development future coronary heart disease (CHD). Low density lipoprotein cholesterol (LDL-C) one most used parameters initiation and follow-up treatment patients with dyslipidemia. It well known fact that LDL-C lowering therapy reduces risk CHD. Therefore, accurate determination levels so...

10.7717/peerj.14544 article EN cc-by PeerJ 2023-01-05

Abstract Purpose Adipose tissue has an important endocrine function by secreting a variety of hormones known as adipokines such Visfatin, Omentin-1, and Chemerin. On the other hand, these are also secreted from places than fatty tissues in girl genital system. The goal this study was to demonstrate secretory status Adipokines patients with Cental Precocious Puberty (CPP) their utility diagnosis Puberty. Method A total 105 were included (53 CPP group 52 control group). following used...

10.21203/rs.3.rs-3847728/v1 preprint EN cc-by Research Square (Research Square) 2024-01-15

Abstract Objectives The cardiovascular mortality risk is greatly increased in patients with chronic kidney disease (CKD), especially dialysis patients, due to atherosclerosis. Platelet activating factor acetylhydrolase (PAF-AH) an enzyme that hydrolyzes platelet (PAF). Valvular calcifications and PAF-AH are associated However, little known about the status of activity valvular calcification patients. Therefore, aim this study was investigate these parameters CKD Methods This included 92...

10.1515/tjb-2023-0263 article EN cc-by Turkish Journal of Biochemistry 2024-02-29

Multiple sclerosis (MS) is a chronic disease that affects the central nervous system in primarily young adults. Although exact etiology of MS unknown, autoimmune mechanisms are thought to play crucial role, especially with CD4+ T cells involved immune response. Inflammatory reactions involving and macrophages commonly observed lesions. B lymphocytes, plasma cells, antibodies also contribute pathogenesis. Neutrophils, monocytes, platelets, key components, roles inflammatory processes, but...

10.7197/cmj.1369992 article EN Cumhuriyet Tıp Dergisi/Cumhuriyet Üniversitesi Tıp Fakültesi dergisi 2024-03-08

Abstract Objectives It is vital to rapid diagnosis and determine the intensive care unit (ICU) requirement early reduce mortality rate in Fournier gangrene (FG) patients. Cell population data (CPD) are parameters obtained from complete blood count (CBC) analysis related activation of different leukocyte subgroups. The study aimed find reliable markers diagnose ICU using CPD. Methods We included 24 patients 22 healthy controls study. CBC analyses were performed by a Sysmex XN-9000 series...

10.1515/tjb-2024-0038 article EN cc-by Turkish Journal of Biochemistry 2024-06-27

The concentration of low-density lipoprotein cholesterol (LDL-C) is recognized as a crucial factor in cardiovascular health. This study aims to conduct comprehensive bibliometric and visual analysis provide review current research trends patterns this area. We retrieved the publications from Web Science (WoS) database conducted analyses using VOSviewer software, bibliometrix R package, biblioshiny web tool. was on 620 original articles papers published between 1990 2023 institutions located...

10.17776/csj.1452125 article EN Cumhuriyet Science Journal 2024-12-30
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