- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Muscle and Compartmental Disorders
- Vasculitis and related conditions
- Central Venous Catheters and Hemodialysis
- Inflammasome and immune disorders
- Renal and Vascular Pathologies
- Blood Pressure and Hypertension Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Gout, Hyperuricemia, Uric Acid
- Parathyroid Disorders and Treatments
- Chronic Kidney Disease and Diabetes
- Iron Metabolism and Disorders
- Systemic Sclerosis and Related Diseases
- Pancreatitis Pathology and Treatment
- Electrolyte and hormonal disorders
- Erythropoietin and Anemia Treatment
- Vitamin D Research Studies
- Pharmacological Effects and Toxicity Studies
- Hemoglobinopathies and Related Disorders
- Autoimmune Bullous Skin Diseases
- Systemic Lupus Erythematosus Research
- Potassium and Related Disorders
- Neurological and metabolic disorders
- Eosinophilic Disorders and Syndromes
Ministry of Health
2015-2025
Sağlık Bilimleri Üniversitesi
2020-2024
University of Health Sciences Antigua
2024
Ankara Atatürk Eğitim ve Araştırma Hastanesi
2022
Education Training And Research
2008-2022
Pediatric Nephrology of Alabama
2012-2020
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2020
Kırıkkale University
2016
Kayseri Eğitim ve Araştırma Hastanesi
2012
Haydarpaşa Numune Eğitim ve Araştırma Hastanesi
2011
Endothelial dysfunction is an early manifestation of vascular injury and contributes to the development atherosclerotic cardiovascular disease. Recent studies have implicated hyperuricemia as a risk factor for We hypothesized that lowering uric acid in subjects with asymptomatic allopurinol might improve endothelial dysfunction, BP, estimated GFR (eGFR), inflammatory markers.Subjects no history gout 30 normouricemic control were enrolled this 4-month randomized prospective study. Thirty...
Abstract Background Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand one of the established potential risk factors for severe coronavirus 2019 (COVID-19). Case morbidity mortality rates any type infection have always been much higher CKD, haemodialysis (HD) RT patients than general population. A large study comparing COVID-19 outcome moderate to advanced CKD (Stages 3–5), HD with a control group is still lacking. Methods We conducted...
Hyperkalemia is a major cause of mortality in the patients who suffer from crush syndrome aftermath earthquakes. The aim this study to investigate frequency and effects hyperkalemia 639 victims catastrophic Marmara earthquake that struck northwestern Turkey, August 1999.Within first week disaster, questionnaires were sent 35 reference hospitals treated victims. Information on serum potassium which was provided 595 out submitted analysis.In admitted within 3 days disaster (n = 401) 5.4 +/-...
Cardiovascular disease in chronic kidney (CKD) is explained part by traditional cardiovascular risk factors; uremia-specific and abnormalities of mineral metabolism, factors involved its regulation, the vascular calcification process.
Carnitine loss through dialysis membranes is shown to be related the lack of carnitine in long-term haemodialysis patients. It has been previously reported that patients might have benefited from supplementation.A total 21 chronic maintaining supplementation and controls (haemodialysis not receiving carnitine) were included study. L-carnitine was used intravenously three times a week after each session, at 20 mg/kg dose. C-reactive protein (CRP), lipid profile, transferrin, albumin levels...
Background Immunoglobulin A nephropathy (IgAN) is the most common primary glomerular disease, characterized by IgA-containing immune complexes in mesangium and mesangial cell proliferation. Proteinuria a strong indicator of progression chronic kidney disease. This study aimed to evaluate relationship between systemic inflammation markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), IgA/complement (C)3, IgA/C4, C3/C4 ratios, proteinuria IgAN patients. Methods...
AbstractThe Marmara earthquake occurred on 17 August 1999. There were 639 renal victims, of whom 477 needed some form replacement therapy. Although several medical complications have been reported in the literature, there has no detailed description infectious patients with crush syndrome after earthquakes. Data from 35 hospitals considering clinical and laboratory findings, as well results microbiological examinations, analysed. 223 out (34.9%) had complications, which comprised most...
Abstract We evaluated the symptoms, changes in laboratory findings during novel coronavirus disease (COVID‐19) pandemic, and effect of depression patients with peritoneal dialysis (PD). This is an observational cross‐sectional study. All were asked to fill clinical assessment form Beck anxiety inventory. Also, last two evaluations this period examined. A total 123 performing PD included. None diagnosed COVID‐19. In study population, parathyroid hormone (PTH), serum albumin, phosphorus...
To evaluate the retinal nerve fiber layer (RNFL) thickness in patients with chronic renal failure (CRF) without diabetes mellitus by using optical coherence tomography (OCT).Sixty-six eyes of 33 CRF were evaluated. Eighteen have been treated hemodialysis (group 1) and 15 peritoneal dialysis 2). The RNFL thicknesses assessed before after group 1. None these had mellitus. Forty 20 age-matched normal control subjects 3. An protocol was used to acquire circular scans 3.4 mm diameter around optic...
Abstract Background The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from databases countries or centers. Here, we present extended results Primary Glomerular Diseases Study Turkish Society Nephrology (TSN-GOLD) Working Group. Methods Data patients who underwent renal biopsy and received diagnosis PGD were recorded in database prepared for study. A total 4399 47 centers evaluated between May 2009 2019. at time kidney analyzed. After exclusion without...
To compare ultrafiltration under continuous ambulatory peritoneal dialysis (CAPD) and automated PD (APD), disclosing potential effects on serum B-type natriuretic peptide (BNP) levels echocardiographic findings.This cross-sectional clinical study included 32 patients CAPD 30 APD without evidence of heart failure or hemodynamically significant valvular disease. Peritoneal equilibration tests, BNP levels, measurements were performed in each subject. also 24 healthy control subjects.Patients...
Hashimoto's thyroiditis (HT) is a common autoimmune thyroid disease with female preponderance. Renal involvement in HT not uncommon. In the present study, we aimed to define frequency and characteristics of glomerular diseases associated further understanding any pathogenesis between disease.We reviewed retrospectively 28 patients who were referred our Department because unexplained haematuria, proteinuria or renal impairment from 2007 2011. Routine laboratory investigations including blood...
Renal artery stenosis (RAS) is a progressive disease and may lead to chronic kidney by deterioration of renal functions. Endothelial dysfunction an important causative factor for damage after RAS revascularization. Nebivolol, new generation beta blocker induces endothelium-related arterial relaxation nitric oxide (NO) improve endothelial dysfunction. This pilot study tested the effect nebivolol on glomerular filtration rate (GFR) in series 33 patients with severe (>70%) who underwent...
Peritoneal dialysis (PD) is one of the commonly used choices continuous renal replacement therapies. membrane damaged by using solutions with lower biocompatibility, peritonitis episodes, and vintage PD therapy. Encapsulating peritoneal sclerosis (EPS) a rare complication presented progressive fibrosis peritoneum. Fibrous tissue entrapment intestine, leading to complete intestinal obstruction, referred as EPS, most severe form sclerosing peritonitis. EPS irreversible usually associated high...
Introduction Despite the developments in modern medicine, acute renal injury is still a challenging and common health problem. It well known that ischaemia reperfusion takes place pathological mechanisms. Efforts to clarify pathophysiology interventions improve outcomes are essential. Our study aimed investigate whether prophylactic use of paricalcitol beneficial ischaemia/reperfusion (I/R) injury. Methods Twenty-four Wistar albino rats were assigned randomly four groups. Right nephrectomies...
Cardiovascular disease (CVD) is the major cause of mortality and morbidity hemodialysis (HD) peritoneal dialysis (CAPD) patients. We aimed to investigate cardiovascular risk factors their correlation with CVD in groups HD CAPD patients.Thirty patients, 30 patients healthy controls were included study. Apolipoprotein A-l (apo A-l), apolipoprotein B B), apolipoprotein(a) [Lp(a)] high-sensitivity CRP (hs-CRP) measured a Beckman Coulter nephelometer, homocysteine (Hcy) was determined an Agilent...