A5009327224- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Parathyroid Disorders and Treatments
- COVID-19 Clinical Research Studies
- Cardiovascular Health and Disease Prevention
- Systemic Sclerosis and Related Diseases
- COVID-19 and healthcare impacts
- Dialysis and Renal Disease Management
- Pregnancy and preeclampsia studies
- Liver Disease Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Blood Pressure and Hypertension Studies
- Biomedical Research and Pathophysiology
- Long-Term Effects of COVID-19
- Inflammatory Biomarkers in Disease Prognosis
- Atherosclerosis and Cardiovascular Diseases
- Organ Donation and Transplantation
- Diabetes and associated disorders
- Bone health and osteoporosis research
- Inflammation biomarkers and pathways
- Electrolyte and hormonal disorders
- Pancreatitis Pathology and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Sarcoidosis and Beryllium Toxicity Research
Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi
2020-2023
Sağlık Bilimleri Üniversitesi
2020-2023
Yedikule Teaching Hospital
2021
Gülhane Askerî Tıp Akademisi
2006-2015
Military Medical Academy
2013-2014
Karolinska Institutet
2014
Turkish Armed Forces
2013
Kastamonu University
2012
General Hospital of Attica
2011
Abstract Background Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand one of the established potential risk factors for severe coronavirus 2019 (COVID-19). Case morbidity mortality rates any type infection have always been much higher CKD, haemodialysis (HD) RT patients than general population. A large study comparing COVID-19 outcome moderate to advanced CKD (Stages 3–5), HD with a control group is still lacking. Methods We conducted...
<b><i>Background: </i></b>Magnesium is an essential ion for all living cells because over 300 enzymes require the presence of magnesium their catalytic action. To date, no group has evaluated as a cardiovascular risk factor in chronic kidney disease (CKD) subjects, which closely interrelated factors and potential confounders such endothelial dysfunction, insulin resistance (the homeostasis model assessment (HOMA) index) inflammation (expressed serum C-reactive protein...
Summary Background and objectives Both prolactin clearance production are altered in CKD. In nonrenal populations, emerging evidence suggests that participates the atherosclerotic process. Given elevated cardiovascular risk of CKD, this study examined links between prolactinemia, vascular derangements, outcomes. Design, setting, participants, & measurements This observational was conducted two cohorts: one with 457 nondialyzed CKD patients (mean age 52±12 years; 229 men) flow-mediated...
Deterioration of kidney function impairs testosterone production, with hypogonadism being common in men chronic disease (CKD). In nonrenal populations, is suggested to participate the atherosclerotic process. male dialysis patients, we showed that low increases risk mortality. We here studied plausible links among levels, vascular derangements, and cardiovascular events nondialysis CKD men.This was a cross-sectional analysis which flow-mediated dilation (FMD) assessed 239 patients (stages 1...
The chronic kidney disease (CKD)-mineral and bone disorder (MBD) syndrome is an important contributor to the CKD-associated cardiovascular high mortality rates. Sclerostin, a protein synthesized in osteocytes, potent downregulator of metabolism novel candidate for bone-vascular axis CKD patients. We tested whether serum sclerostin values are predictive all-cause events (CVEs) population.Serum was obtained from 173 (stage 3-5) 47 control patients, its concentration correlated with estimated...
Acute kidney injury (AKI) is common in coronavirus disease-2019 (COVID-19) and the severity of AKI linked to adverse outcomes. In this study, we investigated factors associated with in-hospital outcomes among hospitalized patients COVID-19 AKI.
Cardiovascular disease (CVD) risk is substantially increased in subjects with chronic kidney (CKD). The Triglycerides (TG) to High-Density Lipoprotein Cholesterol (HDL-C) ratio an indirect measure of insulin resistance and independent predictor cardiovascular risk. No study date has been performed evaluate whether the TG/HDL-C predicts CVD patients CKD.A total 197 (age 53±12 years) CKD Stages 1 5, were enrolled this longitudinal, observational, retrospective study. ratio, HOMA-IR indexes,...
The recent outbreak of COVID-19 rapidly spread worldwide. Comorbid diseases are determinants the severity infection and mortality. aim this study was to explore potential association between chronic kidney disease (CKD) infection.The included 609 consecutive adult patients (male: 54.52%, mean age: 59.23 ± 15.55 years) hospitalized with diagnosis in a tertiary level hospital. Data were collected from electronic health records separated into two groups: Group I COVID-19-positive CKD stage 1-2,...
<b><i>Background/Aims:</i></b> The role of chronic kidney disease-mineral bone disorder (CKD-MBD) reversibility in the amelioration vascular function and reduction risk for cardiovascular events after renal transplantation is still unknown. <b><i>Methods:</i></b> We investigated longitudinal relationship between main biomarkers CKD-MBD evolution [flow-mediated dilatation (FMD)] a series 161 patients with failure maintained on dialysis (5D-CKD)....
Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period not been published extensively.We conducted a national, multicenter observational study that included adult maintenance HD recovered from confirmed A control group without COVID-19 was selected in same center. We investigated characteristics follow-up compare them with non-COVID-19 group.A total 1223 (635 group, 588 group) 47 centers were...
The role of reversibility nontraditional risk factors, like inflammation and CKD-mineral bone disorder, in the reduction cardiovascular after renal transplantation is still scarcely defined.The longitudinal relationship between C-reactive protein, disorder biomarkers, intima media thickness was investigated a series 178 patients (age=32±10 years) with stage 5 CKD maintained on chronic dialysis who underwent echo-color Doppler studies carotid arteries before transplantation. Smokers diabetes...
Abstract Background The largest data on the epidemiology of primary glomerular diseases (PGDs) are obtained from databases countries or centers. Here, we present extended results Primary Glomerular Diseases Study Turkish Society Nephrology (TSN-GOLD) Working Group. Methods Data patients who underwent renal biopsy and received diagnosis PGD were recorded in database prepared for study. A total 4399 47 centers evaluated between May 2009 2019. at time kidney analyzed. After exclusion without...
<b><i>Background/Aims:</i></b> Ramipril attenuates renal Fibroblast growth factor-23 (FGF-23) expression, ameliorates proteinuria and normalizes serum phosphate in the diabetic Zucker rat with progressive disease suggesting that renoprotective effect by this drug may be part due to a FGF-23-lowering of angiotensin-converting enzyme (ACE) inhibition. <b><i>Methods:</i></b> In nonrandomized study, we tested whether ACE-inhibition reduces...
Objectives. Secondary amyloidosis is the most important complication of FMF and endothelial function more severely impaired. Elevated asymmetric dimethyl arginine (ADMA) may mediate excess cardiovascular disease (CVD) risk this group. We aimed to compare characteristics, including ADMA, in patients with FMF-related primary glomerulopathies define factors for a CVD event.
Objective Older adults with co-morbidities have been reported to be at higher risk for adverse outcomes of coronavirus disease 2019 (COVID-19). The characteristics COVID-19 in older patients and its clinical different kidney groups are not well known. Methods Data were retrieved from a national multicentric database supported by Turkish Society Nephrology, which consists retrospectively collected data between 17 April 2020 31 December 2020. Hospitalised aged 18 years or confirmed diagnosis...
Soluble TWEAK (sTWEAK) and asymmetric dimethyl arginine (ADMA) concentrations have been associated with endothelial function in patients chronic kidney disease (CKD). We tested the hypothesis that improvement observed after renal transplantation is directly linked to normalization of both sTWEAK ADMA.One hundred seventy-five transplant recipients (71% men; 31·6 ± 9·4 years) were studied immediately before on 180th day post-transplantation. At each visit, blood samples taken assess...