- Dialysis and Renal Disease Management
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Central Venous Catheters and Hemodialysis
- Long-Term Effects of COVID-19
- Gout, Hyperuricemia, Uric Acid
- Parathyroid Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Renal and Vascular Pathologies
- Muscle and Compartmental Disorders
- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Case Reports on Hematomas
- Pancreatitis Pathology and Treatment
- Vascular Procedures and Complications
- Pneumocystis jirovecii pneumonia detection and treatment
- Infections and bacterial resistance
- Streptococcal Infections and Treatments
- Pharmacological Effects and Toxicity Studies
- Pharmacological Effects of Natural Compounds
- NF-κB Signaling Pathways
- Olfactory and Sensory Function Studies
- Burkholderia infections and melioidosis
- Liver Disease and Transplantation
- Growth Hormone and Insulin-like Growth Factors
Muğla University
2015-2024
Istanbul University
2022
Creative Commons
2022
Sivas State Hospital
2015
Ministry of Health
2010-2013
Education Training And Research
2011-2012
Pediatric Nephrology of Alabama
2012
Ankara University
2010
Başkent University
2005-2007
Hospital Universitario de La Princesa
2007
Endothelial dysfunction is an early manifestation of vascular injury and contributes to the development atherosclerotic cardiovascular disease. Recent studies have implicated hyperuricemia as a risk factor for We hypothesized that lowering uric acid in subjects with asymptomatic allopurinol might improve endothelial dysfunction, BP, estimated GFR (eGFR), inflammatory markers.Subjects no history gout 30 normouricemic control were enrolled this 4-month randomized prospective study. Thirty...
Abstract Background Chronic kidney disease (CKD) and immunosuppression, such as in renal transplantation (RT), stand one of the established potential risk factors for severe coronavirus 2019 (COVID-19). Case morbidity mortality rates any type infection have always been much higher CKD, haemodialysis (HD) RT patients than general population. A large study comparing COVID-19 outcome moderate to advanced CKD (Stages 3–5), HD with a control group is still lacking. Methods We conducted...
Abstract Background Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19). The aim of this study was to describe clinical, laboratory, and radiologic characteristics determinants mortality in a large group MHD hospitalized COVID-19. Methods This multicenter, retrospective, observational collected data from 47 nephrology clinics Turkey. Baseline laboratory radiological characteristics, COVID-19 treatments during hospitalization, need intensive...
Real-Time Elastography for Distinguishing Angiomyolipoma From Renal Cell Carcinoma: Preliminary ObservationsSinan Tan1, Muhammed Fuat Özcan2, Fatih Tezcan1, Serdar Balcı3, Mustafa Karaoğlanoğlu1, Bülent Huddam4 and Halil Arslan1Audio Available | Share
IgA nephropathy (IgAN) is an immune complex-mediated glomerulonephritis characterized by the deposition of IgA-dominant complexes in mesangium, leading to mesangial proliferation and subsequent renal injury. Clinically, IgAN often manifests as episodic macroscopic hematuria following upper respiratory tract or gastrointestinal infections. Disease progression variable, with 20–50% patients advancing end-stage disease within 10–20 years diagnosis. Although primarily idiopathic, it may also...
Objectives: Fabry's disease is an X-linked inherited, rare, progressive, lysosomal storage disorder, affecting multiple organs due to the deficient activity of α-galactosidase A (α-Gal A) enzyme. The prevalence has been reported be 0.15–1% in hemodialysis patients; however, information on chronic kidney not dialysis lacking. This study aimed determine disease.Methods: patients older than 18 years, enclosing KDIGO 2012 definitions, dialysis, were enrolled. Dried blood spots Guthrie papers...
Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period not been published extensively.We conducted a national, multicenter observational study that included adult maintenance HD recovered from confirmed A control group without COVID-19 was selected in same center. We investigated characteristics follow-up compare them with non-COVID-19 group.A total 1223 (635 group, 588 group) 47 centers were...
Hashimoto's thyroiditis (HT) is a common autoimmune thyroid disease with female preponderance. Renal involvement in HT not uncommon. In the present study, we aimed to define frequency and characteristics of glomerular diseases associated further understanding any pathogenesis between disease.We reviewed retrospectively 28 patients who were referred our Department because unexplained haematuria, proteinuria or renal impairment from 2007 2011. Routine laboratory investigations including blood...
Peritoneal dialysis (PD) is one of the commonly used choices continuous renal replacement therapies. membrane damaged by using solutions with lower biocompatibility, peritonitis episodes, and vintage PD therapy. Encapsulating peritoneal sclerosis (EPS) a rare complication presented progressive fibrosis peritoneum. Fibrous tissue entrapment intestine, leading to complete intestinal obstruction, referred as EPS, most severe form sclerosing peritonitis. EPS irreversible usually associated high...
Introduction Despite the developments in modern medicine, acute renal injury is still a challenging and common health problem. It well known that ischaemia reperfusion takes place pathological mechanisms. Efforts to clarify pathophysiology interventions improve outcomes are essential. Our study aimed investigate whether prophylactic use of paricalcitol beneficial ischaemia/reperfusion (I/R) injury. Methods Twenty-four Wistar albino rats were assigned randomly four groups. Right nephrectomies...
Background The metabolic syndrome, syndrome X, is a group of disorders in which insulin resistance plays pivotal role. MS an important risk factor for subsequent development type 2 diabetes and cardiovascular disease. Fetuin‐A liver derived blood protein that acts as effective inhibitor soft tissue calcification. Cystatin C useful marker measuring glomerular filtration rate. Moreover, recently it has been suggested cystatin may be potential biomarker detecting microalbuminuria....
Patients diagnosed with chronic kidney disease (CKD) have a greater rate of cardiovascular mortality when compared the general population. The soluble form TNF-like weak inducer apoptosis (TWEAK) and monocyte chemoattractan protein 1 (MCP-1) play important roles in cellular proliferation, migration apoptosis. current study aimed to analyze whether TWEAK (sTWEAK) MCP-1 levels are associated severity coronary arterial (CAD) CKD patients.Ninety-seven patients stages 2-3 according their...
Hemodialysis (HD) is a technique that helps in the management of drug intoxications/overdoses - most important point being protein-binding rate molecules which have to be cleared. In cases where not bound proteins, conventional HD may effective enough, but if highly proteins then insufficient effective. Hemoperfusion and albumin dialysis are therefore appropriate alternatives. Herein we report case carbamazepine intoxication treatment was performed.
Aim and background: Central venous catheter (CVC)-related blood stream infection is a major cause of morbidity mortality in patients with end-stage renal diseases. However, CVCs are quite frequently required for vascular access hemodialysis (HD) patients. Tunneled catheters (TCs) widely used when needed long period. long-term survival limited by TC-related infections. The purpose this prospective study was to assess clinical outcomes prophylactic antibiotics administration prior insertion...
Abstract Sclerosing encapsulated peritonitis (SEP) is a rare complication of long term peritoneal dialysis. Renin‐angiotensin‐aldosterone system (RAAS) may play role in the development fibrosis CAPD patients. We aimed to evaluate effect aliskiren, valsartan, and aliskiren + valsartan therapy on SEP. The study included 30 Wistar albino rats which were divided into five groups: I (Control) SF solution i.p.; II (CG group) chlorhexidine gluconate III oral plus CG IV V oral, i.p. On twenty‐first...
Chronic anemia, transfusion-associated iron deposition, and chelating agents lead to renal impairment in β-thalassemia (β-thal) patients. The present study aimed determine the most reliable practical method assessing predicting injury β-thal major (β-TM) Therefore, we assessed predictive values of urine β2-microglobulin (β2-MG) neutrophil gelatinase-associated lipocalin (NGAL) levels, their ratios creatinine, serum endocan level. Sixty β-TM patients 30 healthy controls were included. Renal...