A5101999654- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Dermatological and COVID-19 studies
- COVID-19 Impact on Reproduction
- Long-Term Effects of COVID-19
- Renal Diseases and Glomerulopathies
- Inflammatory Biomarkers in Disease Prognosis
- COVID-19 epidemiological studies
- Parathyroid Disorders and Treatments
- Vitamin D Research Studies
- Pancreatitis Pathology and Treatment
- COVID-19 and healthcare impacts
- Chronic Kidney Disease and Diabetes
- Adipokines, Inflammation, and Metabolic Diseases
- Anesthesia and Sedative Agents
- Renal Transplantation Outcomes and Treatments
- Advanced MRI Techniques and Applications
- Neurological Complications and Syndromes
- Vascular Procedures and Complications
- Systemic Sclerosis and Related Diseases
- Family Caregiving in Mental Illness
- Lysosomal Storage Disorders Research
- Blood properties and coagulation
- Metabolism, Diabetes, and Cancer
- Central Venous Catheters and Hemodialysis
Sakarya University
2016-2023
Sakarya Eğitim ve Araştırma Hastanesi
2019-2021
CARE USA
2020
Mortality prediction in the intensive care unit (ICU) is essential patient management. Emerging methods such as machine learning (ML) can be employed to predict ICU patients' mortality. Patients receiving treatment of internal medicine department were subjected ML analysis upon admission, considering demographic, laboratory, and medical scores. Data from 787 patients analyzed, with only a subset (220) included study for 30-day mortality model. The performance boosting, Logistic Regression...
The efficacy of the inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine has not been fully elucidated across whole spectrum patients on kidney replacement therapy. We aimed to characterize long-term antibody response SARS-CoV-2 administered in transplant recipients (KTRs) and hemodialysis (HD) patients. performed this prospective observational study 50 HD, 64 KTR, 41 healthy control groups (HG) given two doses CoronaVac. measured anti-Spike antibodies after 28...
SUMMARY AIM The aim of this study is to analyze the prognostic significance ABO and Rh blood group antigens along with various parameters in patients followed-up diagnosis COVID-19. METHODS We evaluated 397 who were follow-up treated due COVID-19 infections. ages, genders, chronic diseases, antigens, admission rates Intensive Care Units (ICU), mortality analyzed. FINDINGS mean age was 47±17 years. In analysis patients, A Rh-positive (A +) most frequently seen type (176 44.3%) followed by O...
Background/aim: The purpose of this study is to evaluate serum pentraxin-3 (PTX-3) levels in Sars-CoV-2 virus infection (COVID-19) patients and investigate whether PTX-3 predicts the disease prognosis. Materials methods: This was conducted on 88 confirmed COVID-19 who were hospitalized due symptomatic pneumonia between April 15 August 15, 2020. divided into two groups as survived non-survived patients. Both compared according demographic features, comorbid conditions measurement other...
To evaluate the relationship of vitamin D status and replacement therapy with glycemic control, serum uric acid (SUA) levels, microalbuminuria (MAU) in patients type 2 diabetes (T2DM) chronic kidney disease (CKD). Subjectsand Methods: A total 1,463 T2DM CKD (aged 14-88 years), 927 females 536 males, were included this study. The data 25-hydroxyvitamin D, i.e., 25(OH)D, level, SUA, hemoglobin (Hb)A1c, creatinine, estimated glomerular filtration rate, urine albumin-to-creatinine ratio (UACR)...
This study aims to evaluate the effect of primary percutaneous coronary intervention (PCI) and thrombolytic therapy (TT) on in-hospital adverse events, long-term mortality in patients over 65 years age with acute ST-segment elevation myocardial infarction (STEMI).A total 111 retrospectively screened (73 males, mean age: 73.4 ±5.9 years) STEMI, who underwent TT or PCI, were included study. Patients' characteristics, outcomes, 6-month 1-year mortalities recorded.Our was conducted STEMI 38...
SUMMARY INTRODUCTION This study aims to evaluate changes in hematological parameters after the follow-up of patients who received treatment with favipiravir due COVID-19 infections. METHODS Sixty-two cases receiving for at least five days infection were evaluated retrospectively. Parameters including age, gender, nasopharyngeal swab positivity, and chronic diseases analyzed. Hematologic analyzed before treatment. RESULTS The mean age was 63.7±12.3 years. Nasopharyngeal positivity detected...
Introduction: The aim of this study is to investigate whether macrophage migration inhibitory factor (MIF) predicts the prognosis COVID-19 disease.
 Methodology: This descriptive and cross-sectional was conducted on 87 confirmed patients. patients were separated into two groups according admission in ICU or ward. MIF determined batchwise plasma obtained as soon admitted. Both compared with respect demographic characteristics, biochemical parameters prediction requirement...
We aimed to identify clinical settings of renal transplant patients with COVID-19.
No effective treatment has yet been found for SARS-Cov-2, which caused a pandemic outbreak in 2019. It is crucial to detect the progression of COVID-19 patients as early possible. Fibrinogen albumin ratio (FAR) used new inflammatory marker. We aimed find out whether use FAR predictor mortality provides clinical benefit.Data from 590 with March 15, 2020 January 2021 medicine wards and intensive care units (ICU) were retrospectively analysed. Demographic data other laboratory markers collected...
Objective: To investigate and compare complete blood count biochemistry parameters such as c-reactive protein/albumin (CRP/ALB) ratio, procalcitonin/albumin (PRO/ALB) lymphocyte/monocyte (LYM/MON) platelet/lymphocyte (PLT/LYM) ratio of the recovered/deceased, ICU (intensive care unit) /ward patients with COVID-19.
SUMMARY INTRODUCTION: This study aims to determine the incidence of de novo nephritic syndrome (NS) in COVID-19 patients and identify its associated factors. METHODS: All ward with pneumonia were investigated. After determining inclusion exclusion criteria, population was identified. The urine dipstick test protein creatinine ratio (UPCR) measurements performed. Patients NS findings, nasopharyngeal swab, RT-PCR tests performed simultaneously RESULTS: descriptive cross-sectional conducted 21...
Objective: To analyse whether prealbumin could be a new biomarker for predicting mortality in severe COVID-19 patients.Study Design: An observation study.
SUMMARY OBJECTIVE: In this study, we aimed to determine fibroblast growth factor 23, soluble alpha klotho, osteocalcin, indoxyl sulphate, sclerostin, Procollagen 1 N Terminal Propeptide, and beta-CrossLaps levels in hemodialysis peritoneal dialysis patients, compare the of these markers among as well healthy individuals. METHODS: The study included 30 23 patients who were followed-up for at least six months Sakarya University Hospital, besides volunteers. RESULTS: participants divided into...
Aim: In this study, we aimed to measure neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) levels in brachial retinal vein occlusion (BRVO) patients determine whether there it could be used as a marker for BRVO. Brachial is serious disease that causes vision loss associated with inflammation.Material Methods:This retrospective study included 77 BRVO 69 healthy controls. was diagnosed ophthalmic examination. Blood samples were obtained from venous blood serum neutrophil,...
Objective: SuPAR is known as a marker for inflammation. In this study, we aimed to analyse suPAR levels and its correlation with disease prognosis in COVID-19 patients. Method: Demographical, clinical laboratory data of the 36 patients were recorded. Existence other parameters along was studied. Result: Of included 15 female (42%) 21 male (58%). The median age mortality 73 (min-max ,IR;49-88, 25), no 72 ,IR;47- 83, 21) revealing statistically non-significant difference (p=0,596). Among lab...
Objective: We aimed to evaluate the long-term graft functions of kidney transplant recepients (KTR) who have been cured COVID-19 and investigate role inactivated vaccine in clinical course disease.Materials Methods: KTR had pneumonia between March 2020 September 2021 were included study.. The disease was evaluated vaccinated patients compared with those not vaccinated. laboratory information at time admission hospital, 6 months 12 after recorded.Results: Of 83 included, 67.5% male. developed...
Amaç: 2019 aralık ayında başlayan Sars-Cov-2 adı verilen koronavirüs ailesine ait olan nedeniyle mart 2020 tüm dünyada pandemi ilan edildi ve virüsün yol açtığı hastalık Covid-19 olarak anılmaya başlandı. Yaklaşık 176.000.000 kişiyi etkileyen pandemide 12/06/21 tarihi ile 3.500.000 dan fazla insanın vefat ettiği bildirilmiştir. Hipertansiyon tanısı hastalarda hastalarında ölüm oranlarının, hastane yatışlarının gelişen diğer komorbiditelerin daha olduğu bilinmektedir. CRP, fibrinojen, D-dimer...
Amaç: SARS-CoV-2 virüsünün etkeni olduğu COVİD-19 enfeksiyonu salgın oluşturan önemli bir hastalıktır. hastalarının birçoğunda kanama ve pıhtılaşma bozukluklarının geliştiği yapılan çalışmalarla gösterilmiştir. Çalışmamızda, ağırlıklı olarak eğilimi gözlenen bu hasta grubunda, vücudun doğal antikoagülan proteinleri olan Antitrombin-3 (AT3), protein C (PC) S (PS) düzeylerinin incelenmesi amaçlandı. Gereç Yöntemler: 15 Mart-31 Mayıs tarihleri arasında COVID-19 tanısıyla hastaneye yatışı 22...
Background: Many hemodialysis patients need support at various levels from their relatives while performing daily activities. The ‘burden’ of these needs on and negative effects lives have been shown in the literature. aim study was to evaluate ‘care burden’ terms patient.Methods: patient who had received for least 3 months included study. A identification form including demographic data medical history prepared. Perceived care burden scale, Beck depression scale WHO Quality life...
<b>Objective:</b> This research aims to analyze the HALP. (hemoglobin, albumin, lymphocyte. platelet) score of.survivor-deceased Covid-19 patients.<br /> <b>Material and methods: </b>590 patients with. were. included. in. this. study. Patients. divided. into two groups as survivor (n:296) deceased (n:294). Patient information was collected from hospital online system. The Study conducted retrospectively, it to.investigate.the association.between HALP...
The objective was aimed to measure plasma midkine (MK)* levels in patients with COVID-19 and assess its clinical significance. Materials Methods. 88 observed our hospital a diagnosis of were included the study. patients’ demographic characteristics, clinical, laboratory data studied, relationship between MK levels, prognosis, other parameters investigated. Results. Of study, 43 (48.9 %) female 45 (51.1%) male. 24 (27%) died. mean age non-survivors 70 ± 12.3 years survivors 61.9 18.2 years....