A5055881079- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- COVID-19 diagnosis using AI
- COVID-19 Impact on Reproduction
- Dental Research and COVID-19
- Respiratory viral infections research
- Hepatitis C virus research
- Viral gastroenteritis research and epidemiology
- HIV Research and Treatment
- Antibiotic Resistance in Bacteria
- Dermatological and COVID-19 studies
- COVID-19 epidemiological studies
- HIV/AIDS drug development and treatment
- Neonatal Respiratory Health Research
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- Streptococcal Infections and Treatments
- Hepatitis Viruses Studies and Epidemiology
- HIV, Drug Use, Sexual Risk
- Bacterial biofilms and quorum sensing
- HIV, TB, and STIs Epidemiology
- Vitamin D Research Studies
Sakarya University
2018-2025
Sakarya Eğitim ve Araştırma Hastanesi
2020-2024
Ministry of Health of the Russian Federation
2024
CARE USA
2020
Data concerning the presence of SARS-CoV-2 in female genital system is scarce; however, this information important for understanding whether virus can transmit sexually or from mother to child. The aim study was investigate pregnant women with COVID-19 have their lower tract.In cross-sectional study, we present an analysis prospectively gathered data collected at a single tertiary university hospital 19 April May 2020. We included 13 hospitalized suspected COVID-19. Results laboratory tests,...
ABSTRACT A total of 12 new β‐halo alcohols and thiol derivatives were synthesized. Natural alcohol compounds with known pharmacological properties selected as starting substrates, aiming to synthesize that have the potential exhibit biological activity. The synthesis involved a two‐step process, while carried out in three steps. Effective inexpensive methods used for all transformations. Yields ranged from 79% 82%, 66% 71%. Their antibacterial against some gram (+) ( Staphylococcus aureus ,...
We aimed to evaluate the performance of multiplex polymerase chain reaction (PCR)-based FTD gastroenteritis kit (Fast-Track Diagnostics, Esch-sur-Alzette, Luxembourg) and QIAstat-Dx gastrointestinal panel (Q-GP; Hilden, Germany) in detection different enteric pathogens. The molecular test results 320 stool samples from patients with a preliminary diagnosis infectious between July 2019 October 2023 were retrospectively examined, compared conventional results. A single pathogen was detected...
Healthcare personnel are at risk of becoming infected while taking upper and/or lower respiratory tract specimens. Therefore, there is a need for sampling methods that do not infecting them. In this study, we aimed to compare the saliva and Oro-Nasopharyngeal Swab (ONS) methods.Patients were divided into three groups. Group 1 included patients whose diagnosis COVID-19 was confirmed by polymerase chain reaction (PCR). 2 with compatible findings in lung computed tomography (CT), but negative...
The objective of the present study was to investigate presence SARS-CoV-2 in aerosol and COVID-19 contamination distance asssociated with ultrasonic scaling tooth preparation. Twenty-four patients were included this study. Removal supragingival plaque instruments for 10 minutes high-speed air-turbine using simulation cutting maxillary right canine a round diamond bur 5 performed. Patients randomly assigned 2 groups: In group A, medium-volume suction used during treatment. B, high-volume an...
The efficacy of the inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine has not been fully elucidated across whole spectrum patients on kidney replacement therapy. We aimed to characterize long-term antibody response SARS-CoV-2 administered in transplant recipients (KTRs) and hemodialysis (HD) patients. performed this prospective observational study 50 HD, 64 KTR, 41 healthy control groups (HG) given two doses CoronaVac. measured anti-Spike antibodies after 28...
Background/aim: The purpose of this study is to evaluate serum pentraxin-3 (PTX-3) levels in Sars-CoV-2 virus infection (COVID-19) patients and investigate whether PTX-3 predicts the disease prognosis. Materials methods: This was conducted on 88 confirmed COVID-19 who were hospitalized due symptomatic pneumonia between April 15 August 15, 2020. divided into two groups as survived non-survived patients. Both compared according demographic features, comorbid conditions measurement other...
Coronavirus disease 2019 (COVID-19) is an acute inflammatory respiratory disease. Osteopontin (OPN) a glycoprotein expressed in various cell types, such as bone, immune, smooth muscle, epithelial and endothelial cells. It also acts regulator of immune response. The aim the present study was to reveal place serum osteopontin levels predicting severity among patients with COVID-19.
Abstract In this study, it was aimed to investigate bacterial contamination in apheresis platelet suspensions (APS) by automated blood culture system and flow cytometry method (FCM). 33 spiked APS each using 11 strains (5 standard strains, 6 clinical isolates), were prepared three different dilutions (1–10, 10–50, 50-100 cfu/mL), incubated two temperatures (35–37 °C 22–24 °C) incubation times (18–96 h) evaluated FCM. This also inoculated into special bottles (BacT/ALERT® BPA) loaded the...
Objectives: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is mainly transmitted through respiration and direct contact. The status of the infection in female genital system still unknown. study aimed to evaluate whether SARS-CoV-2 present vaginal fluid women with COVID-19 reproductive period. Material methods: Women who were between ages 18–50 years clinically confirmed have at our hospital 20 April–31 May 2020 included study. their menstrual cycle during had a known cervical...
Background: How COVID-19 affects lower urinary tract symptoms (LUTS) in men has not been demonstrated by published research. This study examined the de novo development of LUTS and change severity pre-existing hospitalized with COVID-19. A follow-up period 12 months after infection provided data on long-term effect vs. LUTS. Methods: Data were collected from 70 male patients diagnosed via nasopharyngeal swab RT-PCR technology between June 2020 April 2021. The patient’s age, comorbidities,...
Group A Streptococcus (GAS) is the most common bacterial cause of acute tonsillopharyngitis. In this study, it was aimed to evaluate performance a novel Loop Mediated Isothermal Amplification (LAMP) method in rapid diagnosis GAS samples taken from children with prediagnosis tonsillopharyngitis by comparing culture and antigen test (RAT) methods.A total 100 throat swab at pediatrics outpatient clinic suspected were included study. Throat analyzed RAT, culture, LAMP method. colonies identified...
SUMMARY INTRODUCTION: This study aims to determine the incidence of de novo nephritic syndrome (NS) in COVID-19 patients and identify its associated factors. METHODS: All ward with pneumonia were investigated. After determining inclusion exclusion criteria, population was identified. The urine dipstick test protein creatinine ratio (UPCR) measurements performed. Patients NS findings, nasopharyngeal swab, RT-PCR tests performed simultaneously RESULTS: descriptive cross-sectional conducted 21...
Dünya Sağlık Örgütü (DSÖ), 11 Şubat 2020’de SARS-CoV-2 koronavirüsün neden olduğu hastalığı koronavirus hastalığı-2019 (Coronavirus disease-19 - COVID-19) olarak adlandırmıştır. Ateşi, boğaz ağrısı, öksürüğü ve nefes darlığı olan COVID-19 enfeksiyonu doğrulanmış hasta ile temas öyküsü bulunan bir kişi olası vaka tanımlanır laboratuvar testleri doğrulanması beklenir. Doğrulanmış vaka, pozitif moleküler teste sahip şüpheli durumdur. Vakalar asemptomatik veya ateşsiz de olabilir. Spesifik tanı,...
HCV virus infections are one of the major health problems in world that can cause cirrhosis and liver cancer at a higher rate than other hepatitis data. The aim this study was to determine prevalence mixed with different genotypes Turkey also evaluate current genotype sub-type distributions by multicentered assessment.The data 17,578 C patients collected from 23 centers geographic regions covering all were collected. included information about last 10 years (between 2007 2016), demographic...
Amaç: Geleneksel ve tamamlayıcı Tıp (GETAT) uygulamaları, ilgili alanda sertifikası bulunan hekim ve/veya diş hekimi sorumluluğunda Sağlık bakanlığınca yetkilendirilmiş merkezlerde yapılması gerekmektedir. Eğitimler esnasında standart enfeksiyon kontrol önlemleri/hijyen enfeksiyonlarla alakalı temas bilgisi verilmekte birlikte yetersiz olabileceği düşünülmektedir. Bu çalışmada GETAT uygulayan hekimlere klinikte kurallarının önemini hatırlatma vurgulama amacıyla onların bilgi, tutum...
Diagnosis with reverse transcriptase polymerase chain reaction (RT-PCR) test is a very important step for the control of COVID-19 pandemic. The aim this study to compare RT-PCR results samples taken directly from viral transport medium (VTM) without extraction two different methods, one automated and other manual, in diagnosis COVID-19.Among respiratory tract sent Sakarya Training Research Hospital Microbiology Laboratory COVID-PCR study, 20 negative 43 positive cycle threshold (CT) values...
Our study aimed to evaluate the seropositivity for syphilis in non- immigrant and populations compare results regarding demographic data.In accordance with reverse algorithm, tests were performed between May 2014 December 2018 hospitals our service zone screening or symptomatic disease.A total of 135.328 6.641 screened syphilis. Seropositivity rates 1.3% 3.8% groups (p=0.0001). There was a statistically significant difference terms various age local group (except 18 25 group) (p<0.05)....
SUMMARY OBJECTIVE: This study aimed to investigate the effectiveness of dexamethasone in dialysis patients with COVID-19 and whether it predicts mortality. METHODS: is a comparative cross-sectional 113 consecutive severe pneumonia signs. The were divided into two groups according use treatment: group 1 (n=45) included who treated 2 (n=68) did not receive dexamethasone. RESULTS: mean age both was 67.0±10.6 67.2±13.0 years, respectively (p=0.947). With respect demographic laboratory findings,...
Background:The purpose of this study is to evaluate serum thrombomodulin(TM) levels in coronavirus disease 2019(COVID-19) patients and investigate whether TM predicts the severity COVID-19 coagulopathy . Materials methods:This was conducted on 87 confirmed who were hospitalized due symptomatic pneumonia.The divided into two groups as intensive care unit(ICU) non-ICU patients. Both compared according demographic features, comorbid conditions measurement other laboratory parameters Results:Of...
Introduction: Suppression of Tumorigenicity 2 (ST2) plays a key role in all serious complications that may occur during the COVID-19 disease process, such as systemic inflammatory condition, sepsis, acute respiratory distress syndrome (ARDS), and fibrosis.In this study, we evaluated relationship between serum concentrations soluble ST2 mortality need for mechanical ventilation.Materials Methods: A prospective observational study was conducted from diagnosed patients who presented to...
Objective: This study aimed to determine the seasonal distribution of factor data viral agents determined by multiplex PCR method in routine practice patients admitted hospital with upper respiratory tract infection symptoms and detect oseltamivir resistance viruses that are positive for Influenza A (H1N1). Methods: Nasopharyngeal swab bronchoalveolar lavage samples 354 between ages 0-94 who were Sakarya University Training Research Hospital 12 September 2019 19 February 2020 studied method....
Introduction: Expanded spectrum beta-lactamase is a critical source that limiting the using areas of beta-lactam antibiotics by hydrolysing them.The method to be used for accurate detection ESBL production significant.CLSI and EUCAST are two most commonly standards determination antibiotic susceptibility.This study aimed investigate sensitivity specificity these detection.Methods: This includes 76 producers 74 negative strains, which were isolated from urine specimens sent Medical...