- Fish Biology and Ecology Studies
- Enzyme function and inhibition
- Cholinesterase and Neurodegenerative Diseases
- Phenothiazines and Benzothiazines Synthesis and Activities
- Marine and fisheries research
- Fish Ecology and Management Studies
- Nanomaterials for catalytic reactions
- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Porphyrin and Phthalocyanine Chemistry
- Transboundary Water Resource Management
- Marine and environmental studies
- Inorganic and Organometallic Chemistry
- Oxidative Organic Chemistry Reactions
- Marine Bivalve and Aquaculture Studies
- Chemical Reaction Mechanisms
- Synthesis and Characterization of Heterocyclic Compounds
- Photodynamic Therapy Research Studies
- Agricultural and Rural Development Research
- Molecular Sensors and Ion Detection
- Marine Ecology and Invasive Species
- Synthesis and Catalytic Reactions
- Microwave-Assisted Synthesis and Applications
- Mesoporous Materials and Catalysis
- Natural product bioactivities and synthesis
Sakarya University
2016-2025
Central Marine Fisheries Research Institute
2006-2024
Lahore College for Women University
2009
Ege University
2006
Middle East Technical University
2001
β-Lactams are pharmacologically important compounds because of their various biological uses, including antibiotic and so on. were synthesized from benzylidene-inden derivatives acetoxyacetyl chloride. The inhibitory effect these was examined for human carbonic anhydrase I II (hCA I, II) acetylcholinesterase (AChE). results reveal that β-lactams inhibitors hCA AChE. Ki values (2a–k) 0.44–6.29 nM against 0.93–8.34 II, 0.25–1.13 Our findings indicate inhibit both anhydrases (CA) isoenzymes...
Inland recreational fisheries, found in lakes, rivers, and other landlocked waters, are important to livelihoods, nutrition, leisure, societal ecosystem services worldwide. Although recreationally-caught fish frequently harvested consumed by fishers, their contribution food nutrition has not been adequately quantified due lack of data, poor monitoring, under-reporting, especially developing countries. Beyond limited global harvest estimates, few have explored species-specific patterns,...
ABSTRACT A total of 12 new β‐halo alcohols and thiol derivatives were synthesized. Natural alcohol compounds with known pharmacological properties selected as starting substrates, aiming to synthesize that have the potential exhibit biological activity. The synthesis involved a two‐step process, while carried out in three steps. Effective inexpensive methods used for all transformations. Yields ranged from 79% 82%, 66% 71%. Their antibacterial against some gram (+) ( Staphylococcus aureus ,...
A timeline of commercial fisheries extinctions and a list threatened or extirpated marine species are presented to document the rapidly declining abundance resources in Turkish part Black Sea Marmara Sea. nationally reported data were compared over 50-year period from 1967 (the first year spatially allocated) 2016 assess which now (i.e., earlier present, absent catch data), have become commercially extinct whose declined by 80.0 - 99.9%). The size bony fish caught waters has also strongly...
This study reports the facile synthesis of a novel series benzothiazole-chalcones, in addition to their inhibitory profile on important metabolic enzymes including human carbonic anhydrases (hCA-I, hCA-II) and paraoxonase (PON-1). The inhibition parameters, IC50 (concentration for 50% inhibition) Ki (dissociation constant) values, toward title were determined studied compounds. As result, values hydratase activity range 4.15-5.47 2.56-4.58 μM hCA-I hCA-II, respectively. At same time,...
Bis(3-aminopropyl)amine bonded silica gel (BAPA-SG) was synthesized and characterized by elemental analysis FT-IR spectroscopy, tested for adsorption, preconcentration, recovery of Pd(II) ions. The effective parameters on the preconcentration ions such as pH, volume, flow rate solution, type volume eluent also matrix alkaline heavy metals were investigated. Flame atomic absorption spectrometry used determination concentration. modified could adsorb quantitatively from solutions up to 400 mL...
The reactions of some 1,3-dicarbonyl compounds with cycloheptatriene derivatives in the presence Mn(OAc)_3 were examined. Cycloheptatriene forms mainly [2+3] and [6+3] dihydrofuran addition products derived from cycloheptatriene. However, reaction acetylacetone substituted an electron withdrawing group exclusively gave norcaradiene structure. formation mechanism as well role substituent attached to is discussed.
By the late 20th century, a series of events or 'natural experiments', for example depletion apex predators, extreme eutrophication and blooms invasive species, had suggested that Black Sea could be considered as large ecosystem 'laboratory'. The resulted in regime shifts cascading through all trophic levels, disturbing functioning damaging water environment. Causal pathways by which external (hydroclimate, overfishing) internal (food web interactions) drivers provoke are investigated....
In this study, firstly, (4R)‐2‐(3‐hydroxyphenyl)thiazolidine‐4‐carboxylic acid ( 1 ) and (4R)‐2‐(3‐(3,4‐dicyanophenoxy)phenyl)thiazolidine‐4‐carboxylic 2 were prepared. Then, the novel type metallophthalocyanines (ZnPc 3 ), CuPc 4 CoPc 5 )) bearing thiazolidine groups in peripheral positions synthesized using by compound ). The new compounds 1–5 characterized combination of standard spectroscopic methods such as FT‐IR, H NMR, 13 C UV–Vis spectral data, MALDI‐TOF. Aggregation behaviors...
Abstract A series of carvacrol‐based thiosemicarbazide ( 3a–e ) and 1,3,4‐thiadiazole‐2‐amine 4a–e were designed synthesized for the first time. The structures characterized by nuclear magnetic resonance high resolution mass spectroscopy techniques. All compounds examined some metabolic enzyme activities. Results indicated that all synthetic molecules exhibited powerful inhibitory actions against human carbonic anhydrase I II (hCAI II), acetylcholinesterase (AChE), butyrylcholinesterase...
In this study, simple on–off fluorescent/UV–visible (UV–Vis) probes were easily prepared using 2‐(2‐hydroxyphenyl)thiazolidine‐4‐carboxylic acid ( Sen‐1 ) and/or 2‐(2‐hydroxy‐5‐nitrophenyl)thiazolidine‐4‐carboxylic Sen‐2 for fast detection of Zn 2+ ions. Their sensing properties towards common metal ions investigated UV–Vis and fluorescence spectroscopies. displayed a significant change with the addition in spectra. The induced 104 nm bathochromic shift . binding ratio was determined to be...
A simple, efficient, and practical procedure for the Biginelli reaction using zirconium hydrogen phosphate [Zr(H_2PO_4)_2] as a novel solid acid catalyst is described under solvent-free conditions in high yields. The exhibited remarkable reactivity it reusable.