A5101732602- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Fluorine in Organic Chemistry
- Thermal and Kinetic Analysis
- Energetic Materials and Combustion
- Catalytic C–H Functionalization Methods
- Rocket and propulsion systems research
- Synthesis and Reactions of Organic Compounds
- Crystallography and molecular interactions
- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Radical Photochemical Reactions
- Cyclopropane Reaction Mechanisms
- Carbohydrate Chemistry and Synthesis
- Inorganic Fluorides and Related Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Asymmetric Hydrogenation and Catalysis
- Chemical Synthesis and Analysis
- Catalytic Cross-Coupling Reactions
- Crystal structures of chemical compounds
- Oxidative Organic Chemistry Reactions
- Multicomponent Synthesis of Heterocycles
- Synthesis of Indole Derivatives
- Synthesis and Characterization of Pyrroles
- Biochemical and Molecular Research
Chongqing University of Technology
2023-2024
Sichuan University of Science and Engineering
2015-2024
Beijing Institute of Technology
2023-2024
Sichuan University
2023
China West Normal University
2020
Wuhan University
2020
Zigong First People's Hospital
2016-2019
University of Idaho
2018-2019
Leshan Normal University
2017
Shanghai Institute of Organic Chemistry
2015
Next-generation fused ring energetic materials for different applications were designed by regulating mechanical sensitivity.
A mild and practical protocol for manganese-catalyzed aerobic oxytrifluoromethylation of olefinic bonds styrene derivatives using CF3SO2Na (Langlois' reagent) as the CF3 source is described. distinguishing feature this method generation trifluoromethyl radicals from simple manganese salt/O2 system. The reaction proceeds under ambient conditions, free added peroxide initiators, provides moderate to good selectivities alcohol versus ketone product.
Three classes of nitrogen-rich energetic compounds were obtained from 3,4-dicyano-furoxan.
A novel copper/amine co-catalyzed formal regioselective [3 + 2] cycloaddition reaction of an <italic>O</italic>-acyl oxime with α,β-unsaturated aldehydes is developed.
A mild and efficient strategy for the nitration of amino-substituted pyrazoles/triazole employing a mixture potassium nitrate concentrated sulfuric acid (KNO3/H2SO4) as nitrating reagent proceeded smoothly to give nitramino-substituted products. These were treated with corresponding bases energetic salts 1–10. The compounds fully characterized, single crystal X-ray diffraction studies obtained 1, 4, 6, 10. physical properties detonation performance measured or calculated. Salts 2, 8, 9...
The introduction of energetic groups can significantly increase the density materials usually accompanying with deteriorating safety performance, which has limited creating advanced insensitive materials....
A tunable and highly regio- diastereoselective addition of acyclic silyl dienolates 2 to several α-fluoroalkyl sulfinylimines 1 was developed. By appropriate choice the Lewis acid catalyst, two new chiral amines 3 4 were obtained in good yields excellent diastereoselectivities (up >99 : dr), respectively.
The reaction of indoline-2,3-diones and (triphenylphosphonio)difluoroacetate (PDFA) afforded novel 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles in moderate to excellent yields.
A class of polyazole energetic compounds <bold>(</bold>combination tetrazolyl, dinitromethyl and triazole<bold>)</bold> was obtained from 4,5-dicyanotriazole.
An efficient asymmetric vinylogous Mannich (AVM) addition reaction of 3-alkenyl-2-oxindoles to α-fluoroalkyl aldimines has been developed. This provided various optical active α-alkylidene-δ-amino-δ-fluoroalkyl oxindoles in excellent yields, complete γ-site regioselectivity, and diastereoselectivities.
A series of monosubstituted 1,2,4,5-tetrazine-based energetic materials was effectively synthesized and fully characterized with IR, multinuclear nuclear magnetic resonance (NMR), elemental analyses. Heats formation detonation performances were determined using Gaussian 03 EXPLO5 v6.01 programs, which show that 5 9 as secondary explosives have velocities superior to the current secondary-explosive benchmark, triaminotrinitrobenzene (TATB). Importantly, compounds 2, 5, first single-crystal...
Two advanced energetic materials were synthesized via introducing carbonyl and o -NH 2 –NO groups into fused-ring compounds. A comparative study has demonstrated that the density detonation performance of these could be effectively improved.
A general method was developed for the synthesis of 1-difluoroalkyl isoquinolines via palladium-catalyzed radical cascade difluoroalkylation-cyclization vinyl isocyanides with bromodifluoroacetic derivatives. The difluoroalkylated cyclization products were readily converted to various other valuable gem-difluoro-containing compounds.
We report herein the exploitment of partially fluorinated trifluoroethyl as precatalyst ligands in nickel-catalyzed Suzuki-type alkylation and fluoroalkylation coupling reactions. Compared with [L n NiII(aryl)(X)] precatalysts, unique characters bis-trifluoroethyl imparted [(bipy)Ni(CH2CF3)2] bench-top stability, good solubilities organic media interesting catalytic activities. Preliminary mechanistic studies reveal that an eliminative extrusion a vinylidene difluoride (VDF, CH2[double bond,...
A new and step-economic method for the synthesis of homobenzylic fluorides through nickel-catalyzed Suzuki-type fluoroethylation coupling is developed.
We report herein a facile synthetic method for converting unactivated (hetero)aryl electrophiles into β-fluoroethylated (hetero)arenes via nickel-catalyzed reductive cross-couplings. This coupling reaction features the involvement of FCH2 CH2 radical intermediate rather than β-fluoroethyl manganese species which provides effective solutions to problematic β-fluoride side eliminations. The practical value this protocol is further demonstrated by late-stage modification several complex ArCl or...
Abstract Aluminum powder is commonly used as a metal fuel additive in composite solid propellants. However, its tendency to agglomerate during combustion can lead two‐phase flow losses, negatively impacting energy performance. To address this issue and enhance the performance of aluminum powder, nitrated graphene oxide (NGO) was developed improve dispersion optimize characteristics. Various analytical techniques were employed examine properties, including Fourier‐transform infrared...
A general method for the synthesis of chiral pentacyclic spirooxindoles containing a tetrahydropyrano[2,3-<italic>b</italic>]indole scaffold through one-pot stepwise sequence is reported.