Alex Orădan

ORCID: 0000-0001-5911-983X
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About
Contact & Profiles
Research Areas
  • Reconstructive Surgery and Microvascular Techniques
  • Reconstructive Facial Surgery Techniques
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological Disease Mechanisms and Treatments
  • Breast Implant and Reconstruction
  • Surgical site infection prevention
  • Atherosclerosis and Cardiovascular Diseases
  • Hernia repair and management
  • Ovarian cancer diagnosis and treatment
  • Barrier Structure and Function Studies
  • Renal cell carcinoma treatment
  • Peripheral Artery Disease Management
  • Surgical Sutures and Adhesives
  • Electrospun Nanofibers in Biomedical Applications
  • Oral and Maxillofacial Pathology
  • Acute Ischemic Stroke Management
  • Cancer Research and Treatments
  • Nerve injury and regeneration
  • History of Medical Practice
  • Orthopedic Surgery and Rehabilitation
  • Head and Neck Surgical Oncology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Brain Tumor Detection and Classification
  • Bone fractures and treatments
  • Immune cells in cancer

Iuliu Hațieganu University of Medicine and Pharmacy
2017-2024

Institute of Oncology Prof. Dr. Ion Chiricuta
2019-2024

University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2018

Background: Ever since the description of first microvascular anastomosis, numerous alternative methods have been described to classical approach. Tissue adhesive has shown promising result in previous studies and can be a fast efficient which still requires more allow its clinical implementation. Methods: A randomized comparative experimental study was conducted on rats' femoral arteries an end-to-end anastomosis performed order compare 2 techniques. In one group, simple interrupted suture...

10.1177/22925503211019619 article FR Plastic Surgery 2021-05-28

: Perforator mapping is a mandatory tool for the preoperative planning of microsurgical free flap, especially in breast reconstruction. Numerous methods have been described. In this study, we investigate combined use Dynamic Infrared Thermography (DIRT) and Colour Doppler Ultrasonography (CDUS) only to see whether it can eliminate need Computed Tomography Angiography (CTA).

10.3390/jpm14090969 article EN Journal of Personalized Medicine 2024-09-13

Background. The use of adipose tissue in reconstructive procedures has become popular the last decades due to properties stem cells and mechanical protection. In acute nerve lesions, there have been experimental reports on non-vascularised as an adjuvant for recovery but our knowledge is no published research that describes effect pedicled vascularised (pVAT) injuries. Therefore we decided study pVAT regeneration when wrapped around epineurial coaptation site a 5 mm defect sciatic from rat....

10.33962/roneuro-2024-054 article EN cc-by-nc-nd Romanian Neurosurgery 2024-09-15

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Orădan A, Huțanu Horváth E, Chiriac L, Dobreanu M. IMPROVED RAT STROKE MODEL BY INTRALUMINAL MIDDLE CEREBRAL ARTERY OCCLUSION: A SPECIAL EMPHASIS ON SURGICAL TECHNIQUE. Health Problems of Civilization. 2017;11(3):202-210. doi:10.5114/hpc.2017.70008. APA Orădan, A., Huțanu, Horváth, E., Chiriac, L., & Dobreanu, (2017). Civilization, 11(3), 202-210. https://doi.org/10.5114/hpc.2017.70008 Chicago Alex, Adina Emőke...

10.5114/hpc.2017.70008 article EN cc-by-nc-sa Health Problems of Civilization 2017-01-01

Abstract Introduction : Experimental acute cerebral ischemia quickly triggers circulating inflammatory cells, provoking infiltration of neutrophils and macrophages in the damaged brain region. N-3 polyunsaturated fatty acids alleviate ischemic deterioration, however, their potential effect on bone marrow cell mobilization is less known. Materials methods healthy male Wistar rats were submitted to intraperitoneal saline injection (n=10, sham Group), transient middle artery occlusion (tMCAO)...

10.2478/rrlm-2019-0004 article EN cc-by-nc-nd Revista română de medicină de laborator 2019-01-01

Parotid sialocele is an accumulation of saliva inside a subcutaneous cavity, usually as result trauma or iatrogenic injury the parotid gland duct, which can progress to other complications if left untreated. Numerous treatment options have been described before, but there currently no evidence based consensus. We present case patient treated for with use negative pressure wound therapy. Laryngoscope , 131:E1094–E1095, 2021

10.1002/lary.29078 article EN The Laryngoscope 2020-09-08

Abstract Background The double stitch everting (DSE) technique, in which time is won by leaving the needle inside vessel wall in-between stitching, a modification of end-to-side (ETS) anastomosis interest reducing time. This ensures proper eversion, intima-to-intima contact, and improved suture symmetry. Materials Methods We designed an N-of-1 randomized trial with each microsurgeon as their own control. included 10 microsurgeons different levels experience who were then asked to perform...

10.1055/s-0040-1718548 article EN Journal of Reconstructive Microsurgery 2020-10-14

Abdominal wall reconstruction aims at restoring the anatomical, functional and aesthetic integrity of this region, while providing protection abdominal viscera prevent herniation. There are various techniques used for reconstruction. We present a difficult case performed with pedicled antero-lateral thigh (ALT] flap good postoperative

10.15386/mpr-2383 article EN Medicine and Pharmacy Reports 2022-05-13

Reconstrucţia imediată cu implant la pacientele ptoză mamară semnificativă prezintă numeroase dificultăţi tehnice iar rezultatele estetice favorabile sunt greu de obţinut.Vă prezentăm filizofia noastră privind reconstrucţia macromastie utilizand lamboul dermal inferior, indicaţii şi aspecte practice.Am realizat mastectomie reconstrucţie zece paciente gr.III-IV în cadrul Institutului Oncologic "Prof.Dr. I. Chiricuţă" între iunie 2019 decembrie 2020.Mastectomia a fost efectuată după un tipar...

10.21614/chirurgia.116.2suppl.s127 article RO Chirurgia 2021-01-01

Background and Objective: Clinical experimental observations emphasize the role of inflammation as a direct risk factor for stroke. To better characterize inflammation, we have conducted detailed histological analysis inflammatory cell population after transient middle cerebral artery occlusion in rat model. Methods: Fifteen adult Wistar male rats were divided randomly into test (n=10) sham (n=5) groups. In ischemic group, focal ischemia was induced with an intraluminal filament technique....

10.7287/peerj.preprints.26510v1 preprint EN 2018-02-12

Background and Objective: Clinical experimental observations emphasize the role of inflammation as a direct risk factor for stroke. To better characterize inflammation, we have conducted detailed histological analysis inflammatory cell population after transient middle cerebral artery occlusion in rat model. Methods: Fifteen adult Wistar male rats were divided randomly into test (n=10) sham (n=5) groups. In ischemic group, focal ischemia was induced with an intraluminal filament technique....

10.7287/peerj.preprints.26510 preprint EN 2018-02-12

<h3>Introduction/Background</h3> Interval debulking surgery (IDS) has similar outcomes and less morbidity in comparison with primary advanced ovarian cancer, however, there is controversy regarding the selection of chemotherapy-resistant clones. Complete resection (CR) an essential prerequisite near-infrared (NIS) combined various techniques for highlighting malignant foci striving to achieve true CR. This study investigated role Indocyanine Green (ICG) identifying residual during IDS....

10.1136/ijgc-2022-esgo.707 article EN Ovarian cancer 2022-10-01
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