Rafael Pereira de Souza

ORCID: 0000-0001-5916-9730
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About
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Research Areas
  • Chromium effects and bioremediation
  • Trace Elements in Health
  • Thyroid and Parathyroid Surgery
  • Oral and Maxillofacial Pathology
  • Thyroid Cancer Diagnosis and Treatment
  • Adipose Tissue and Metabolism
  • Cancer, Hypoxia, and Metabolism
  • Tannin, Tannase and Anticancer Activities
  • Cancer-related molecular mechanisms research
  • RNA Research and Splicing
  • Reconstructive Surgery and Microvascular Techniques
  • MicroRNA in disease regulation
  • Muscle Physiology and Disorders
  • Academic Research in Diverse Fields
  • Reconstructive Facial Surgery Techniques
  • Biochemical Analysis and Sensing Techniques
  • Acute Ischemic Stroke Management
  • Facial Nerve Paralysis Treatment and Research
  • Head and Neck Anomalies
  • RNA modifications and cancer
  • Venous Thromboembolism Diagnosis and Management
  • Cancer Research and Treatments
  • Regulation of Appetite and Obesity
  • Thyroid Disorders and Treatments
  • Nutrition and Health in Aging

Instituto do Câncer do Estado de São Paulo
2020-2025

Faculdades Integradas Aparício Carvalho
2021

Cancer Institute (WIA)
2021

Sociedade Brasileira de Cirurgia de Cabeça e Pescoço
2020

Universidade Estadual de Campinas (UNICAMP)
2019

O presente estudo analisou a incidência e os fatores associados às internações por flebite, tromboflebite, embolia trombose venosa no Brasil entre 2020 2024, com base em dados do Sistema de Informações Hospitalares (SIH/DATASUS). Trata-se um descritivo, retrospectivo quantitativo, que avaliou variáveis como ano atendimento, região, faixa etária, sexo, cor/raça óbitos. Os foram tabulados Excel analisados termos frequência absoluta relativa.Os resultados indicaram 216.663 período analisado,...

10.70164/jmbr.v2i2.568 article PT cc-by-nc-nd Journal of Medical and Biosciences Research. 2025-03-07

Sepse pode ser definida como uma disfunção orgânica em decorrência de infecção, podendo levar a sequelas graves e até mesmo óbito. Essa afecção acomete milhões pessoas anualmente, apresenta alta taxa letalidade. O presente estudo visa analisar, forma quantitativa qualitativa, os casos sepse incidentes no Brasil 2024. Para isso, foram utilizados dados internações hospitalares por coletados do Departamento Informática Sistema Único Saúde (DATASUS) ano Foram analisados sociodemográficos dos...

10.70164/jmbr.v2i2.624 article PT cc-by-nc-nd Journal of Medical and Biosciences Research. 2025-03-25

We evaluated the performance of TargetScan, miRDB, and miRWalk for predicting miRNA-mRNA interactions in HNSCC. Based on clinical tumor cancer-free tissue data, emerged as most comprehensive tool. Validation using NanoString technology MiRTarBase confirmed key predictions, highlighting important roles PI3K-Akt Wnt pathways. This study underscores importance integrating bioinformatics experimental data to better understand ■ had highest predicted validated miRNA networks Around 3.3%...

10.31744/einstein_journal/2025ao1372 article EN cc-by Einstein (São Paulo) 2025-01-01

Cancer-associated cachexia is a complex metabolic syndrome characterized by weight loss and systemic inflammation. Muscle fatty infiltration into muscle are associated with poor prognosis in cancer patients. Skeletal secretes myokines, factors autocrine, paracrine and/or endocrine action, which may be modified or play role cachexia. This study examined myokine content the plasma, skeletal tumor homogenates from treatment-naïve patients gastric colorectal stages I-IV (CC, N = 62), not (weight...

10.1016/j.clnu.2020.10.050 article EN cc-by-nc-nd Clinical Nutrition 2020-11-02

The leptin gene product is released into the blood stream, passes through blood-brain barrier, and finds receptor (LEPR) in central nervous system. This hormone regulates food intake, hematopoiesis, inflammation, immunity, differentiation, cell proliferation. LEPR Gln223Arg polymorphism has been reported to alter function expression, both of which have related with prognostics several tumor types. Furthermore, studies shown a relationship between development, its role oral oropharyngeal...

10.4238/2015.november.24.5 article EN Genetics and Molecular Research 2015-01-01

Objective: The objective of this study is to compare the total costs surgery and radiofrequency (RF) ablation for treatment benign thyroid nodules. Materials methods: This a prospective randomized comparing cases treated with US-guided RF (cases) (control). They were selected allocated groups (thyroidectomy or radioablation) by permuted block randomization in blocks five each. Results: Five Ablation compared thyroidectomies conducted [...]

10.20945/2359-3997000000411 article EN cc-by Archives of Endocrinology and Metabolism 2021-11-11

Abstract Oral cancer squamous cell carcinoma (OCSCC) mainly affects individuals aged between 50 and 70 years who consume tobacco alcohol. Tobacco smoke contains hundreds of known toxic carcinogenic molecules, a few studies have sought to verify the relationship such trace elements as risk or prognostic factors for head neck cancer. We obtained 78 samples tumor tissues from patients with OCSCC, performed qualitative elemental characterization using micro X-Ray Fluorescence technique based on...

10.1038/s41598-020-67270-5 article EN cc-by Scientific Reports 2020-06-25

Introduction: Recent interest of physicians and patients to prevent scars in the neck thyroid surgery has fostered development several remote access techniques recent decades. Among various developed, transoral endoscopic thyroidectomy vestibular approach (TOETVA) shown be a safe alternative, selected cases, conventional thyroidectomy. Objective: This study aimed evaluate results TOETVA with nodules compare them those undergoing Methods: Retrospective cohort comparing 31 submitted versus 30...

10.4322/ahns.2020.0004 article EN Archives of Head and Neck Surgery 2020-01-01

Abstract The comparison of chemical and histopathological data obtained from the analysis excised tumor fragments oral squamous cell carcinoma (OSCC) with demographic clinical evolution is an effective strategy scarcely explored in OSCC studies. aim was to analyze tissues for protein expression enzymes related oxidative stress DNA repair trace elements as candidates markers aggressiveness prognosis. Tumor 78 patients that had undergone ablative surgery were qualitatively analyzed by...

10.1038/s41598-021-01753-x article EN cc-by Scientific Reports 2021-11-16

Sistemas inteligentes de monitoramento ônibus são utilizados para fornecer informações em tempo real do veículo como sua localização, aproximação, velocidade média, percurso, entre outras. Esses sistemas agregam valor ao serviço transporte e trazem vários benefícios os usuários gestores. Este trabalho apresenta uma solução Internet das Coisas (em Inglês, IoT - of Things) dos interno passageiros da Unicamp. A batizada Circulino foi desenvolvida 2016 consiste na coleta dados geolocalização...

10.20396/sinteses.v0i7.10131 article PT Resumos... 2019-09-19

Abstract BackgroundSquamous cell carcinoma (OCSCC), the most frequent cancer of oral cavity, is extremely aggressive, response to treatment poor and markers for prognosis disease are scarce. The comparison chemical histopathological data obtained from analysis excised tumor fragments with demographic clinical evolution an effective strategy scarcely explored in OCSCC studies. aim was analyse tissues trace elements protein expression enzymes related oxidative stress DNA repair that can be...

10.21203/rs.3.rs-281302/v1 preprint EN cc-by Research Square (Research Square) 2021-03-08
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