- Dental Implant Techniques and Outcomes
- Temporomandibular Joint Disorders
- Orthodontics and Dentofacial Orthopedics
- Periodontal Regeneration and Treatments
- Oral microbiology and periodontitis research
- Botulinum Toxin and Related Neurological Disorders
- Oral Health Pathology and Treatment
- Medicinal plant effects and applications
- Oral and gingival health research
- Healthcare during COVID-19 Pandemic
- Dental Health and Care Utilization
- Dermatological and COVID-19 studies
- Occupational Health and Burnout
- Dental materials and restorations
- Shoulder Injury and Treatment
- Orthopaedic implants and arthroplasty
- dental development and anomalies
- Laser Applications in Dentistry and Medicine
- Education during COVID-19 pandemic
- Oral and Craniofacial Lesions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Youth, Drugs, and Violence
- Sesquiterpenes and Asteraceae Studies
- Icing and De-icing Technologies
- Extracellular vesicles in disease
Universidade Federal Fluminense
2015-2025
Instituto Nacional de Traumatologia e Ortopedia
2014-2025
Instituto de Saúde
2023
Summary The pain from temporomandibular disorder ( TMD ) is often associated with physical symptoms of other chronic disorders and comorbidities, such as generalised muscle joint pain. However, this association not widely studied. To evaluate the prevalence comorbid in joints, specifically knees, hips, ankles, shoulders, wrists elbows, individuals without . We evaluated 337 patients a public hospital city Rio de Janeiro, Brazil. Research Diagnostic Criteria for questionnaire were used...
There is evidence for a genetic contribution to chronic periodontitis. In this study, we conducted genome wide association study among 866 participants of the University Pittsburgh Dental Registry and DNA Repository, whose periodontal diagnosis ranged from healthy (N = 767) severe periodontitis 99). Genotypingi over half-million single nucleotide polymorphisms was determined. Analyses were done twice, first in complete dataset all ethnicities, second including only samples defined as...
Extracellular vesicles (EVs) are emerging as crucial biomarkers in molecular diagnostics, providing early detection of disease progression. Although ultracentrifugation remains the gold standard for vesicle isolation from biofluids, it has limitations scalability and accessibility. This study presents lyophilization an innovative method preserving EVs isolating microRNAs saliva, utilizing its proven ability to maintain biological activity prevent unwanted chemical reactions. We assessed five...
tHistory of chronic periodontitis (CP) is a risk factor for oseointegration failure. The osteoclastogenesis system (RANK, RANKL and OPG) critical bone homeostatic control. We investigated the levels OPG in peri-implant tissues from volunteers with without history CP their association mucosae inflammation. This single-blind case-contro study. Diagnosis examination was performed on 46 volunteers, divided into control (without CP, n=26) group (with n=20). Gingival biopsies were harvested during...
Objective: To evaluate the association between polymorphisms in genes and comorbid presence of arthralgias TMD.Methods: This is a case-control study. The groups formed were individuals with chronic arthralgia 1) myofascial pain (n = 42); 2) articular 16); 3) multiple diagnoses 69); 4) TMD without some other 5) but joints 82); 6) control group 72). SNPs COMT, ADRB2, HTR1A investigated.Results: CT genotype for COMT (rs9332377) gene was associated absence (p .05). In ADRB2 (rs1042713) gene, AA...
Alternative pretreatment strategies of dentin and adhesionare constantly being developed studied with the goal improving adhesion resin restorative materials this tissue. The objectives present study were to evaluate ability airborne-particle abrasion (APA) aluminum oxide on remove smear layer effects produced microstructure.The phosphoric acid (PA) was used for a comparison. For that, 20 human third molars randomly allocated into two experimental groups, according method used: G1 (N = 10) -...
Abstract Despite the success of osseointegrated implants, failures have increased significantly, associated with development peri-implantitis. Multiple factors influence peri-implant bone loss, including environmental and genetic causes. BMPs (Bone morphogenetic proteins) are growth that induce formation. FGF (fibroblast factors) their receptors (FGFRs) play important roles by controlling levels cell proliferation, differentiation migration. BMP/FGF relationship is responsible for promoting...
Subjects susceptible to chronic periodontitis (CP) show a high risk for the development of periimplantitis (PI). Both diseases are multifactorial, presenting similarities in their pathophysiology and polygenic profile. MMP-13 (matrix metalloproteinases 13/ collagenase 3) is collagenolytic enzyme, which expression induced by TGF beta 3 (transforming growth factor type human gingival fibroblasts inhibited TIMP-2 (tissue inhibitor metalloproteinase 2). The aim this study was investigate...
A anquilose da articulação temporomandibular é a fusão entre o côndilo mandibular e cavidade glenóide, gerando restrição aos movimentos articulares, função mastigatória limitada além de consequências estéticas psicossociais.A condição ainda apresenta influência no desenvolvimento facial, erupção posicionamento dentários quando ocorre em pacientes crescimento.O estudo relata um caso clínico AATM unilateral esquerda com infecção otológica prévia.A alteração evoluiu completa impossibilidade...
Dentistry constitutes the basic nucleus of professionals higher level health in Brazil with one largest concentrations dentists per capita world. However, genetic dentistry is explored, basically, research field. Future actions need to be performed order deep whole knowledge about diagnosis and treatment diseases basis dentistry, Brazil.
Geographic Tongue (GT) is a benign inflammatory disorder of unknown etiology, which characterized by the loss epithelium due to atrophy filiform papillae. It usually occurs on dorsum tongue and may extend its lateral edges. appears as an erythematous area surrounded whitish slightly elevated margins. In most cases, condition asymptomatic, although some individuals report symptoms that include burning sensation tongue.Assess whether there was change in clinical aspect during COVID-19...
The present study aimed to evaluate the influence of manual torque (10 Ncm) versus clinical (30 Ncm), which is recommended by manufacturer, on total length morse cone implant abutments. Twenty specimens were prepared and distributed into two groups: group 1 with ten analogs for type implant, 2 implants, size 4.3 × 15 cm. In each group, distance between platform top prosthetic abutment (abutment height) was measured subjected a 10 Ncm. Then, 30 Ncm applied same abutment, height measured....
This study aimed to evaluate the correlation between epidermal growth factor (EGF) and receptor (EGFR) levels in different clinical stages of dental implant rehabilitation trace mucositis development’s biological profile. Thirty-six participants from Specialization Implant Dentistry, Universidade Federal Fluminense, Brazil, were included underwent sample collection: inside alveolar socket, immediately before placement (Group 1, n = 10); at peri-implant crevicular fluid (PICF) during...
Peri-implant mucosae inflammation during osseointegration period can promote host response imbalance and bone resorption by bacteria infiltration. Aim: To evaluate the association between EGF EGFR gene expressions in peri-implant tissue with period. Material Methods: Forty-nine participants, 59 endosseos implants, were recruited for this study. All participants included rehabilitated implants two stages surgical protocol, presenting favorable quality quantity. Osseointegration was evaluated...
Aim: To evaluate the active tactile sensitivity in individuals with complete natural dentition, determining smallest thickness detected by participants, and clarifying if there is a difference between thicknesses analyzed.Materials methods: Active was evaluated 40 research participants.Inclusion criteria included participants without or history of periodontal disease, absence temporomandibular disorders, bruxism, restorations area.Exclusion age below 18 years.The perception threshold using...
O bruxismo é definido como uma atividade repetitiva dos músculos mastigatórios caracterizada pelo ranger e/ou apertar de dentes com diferentes manifestações circadianas. Devido à complexidade da condição e a variedade distúrbios associados ressalta-se necessidade um conhecimento detalhado sobre possíveis fatores individuais fim direcionar conduta específica para consequências do bruxismo. A obtenção dados genético-moleculares estudo possível relação entre genética acarretaria em melhor...
The pilot study aimed to evaluate the association between presence of Temporomandibular Joint Ankylosis (TMJA) and expression profile RANKL (nuclear kappa-B receptor activator factor/ligand) OPG (osteoprotegerin) genes.
Objective: Report a case of passive geographic tongue that became active due to the presence severe stress associated coronavirus disease 2019 (COVID-19) pandemic. Case details: In January 2019, 42-years-old Caucasian female was included in survey on (GT). At time, although she reported having condition, intraoral examination, no atrophic areas or whitish margins were observed her (classic clinical signs GT). November 2020, contacted again and changes GT. this lateral borders presented...