A5057720815- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Chemical and Physical Properties in Aqueous Solutions
- Analytical Chemistry and Chromatography
- Phase Equilibria and Thermodynamics
- Crystallography and molecular interactions
- Advanced Photocatalysis Techniques
- Advanced Data Processing Techniques
- Safety and Risk Management
- ZnO doping and properties
- Simulation and Modeling Applications
- Enzyme Structure and Function
- Pharmacological Effects of Natural Compounds
- Chemical Thermodynamics and Molecular Structure
- Gas Sensing Nanomaterials and Sensors
University of Technology Malaysia
2025
State Key Laboratory of Chemical Engineering
2019-2020
Tianjin University
2018-2020
Tianjin Institute of Pharmaceutical Research (China)
2019-2020
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2018-2020
Nanjing University of Science and Technology
2016
Poor solubility and dissolution property of pharmaceuticals largely limits their bioavailability efficacy, development a multicomponent crystal is one the effective approaches to potentially address issue. Herein we investigated structure relationship aiming improve pharmaceutical property, using Biopharmaceutics Drug Disposition Classification System class II antipsychotic drug Aripiprazole (APZ) as model compound. We reported six new discovered crystals APZ salts with all pharmaceutically...
As global populations age, ensuring the mobility safety of elderly individuals has become a prominent concern, highlighting need for innovative designs in assistive products seniors. This study aims to offer scientific and practical design methodology aid designers, validated through walker users. To begin, potential user needs walkers were identified using User Journey Mapping, with these categorized Kano model establish structured hierarchy requirements. Then, Analytic Hierarchy Process...
Glibenclamide (GCM) is an oral antihyperglycemic drug and widely used to treat type-II diabetes. The quality of the GCM product impacts efficacy medicine. However, determined by crystallization process, in which solubility property plays a significant role. In this study, 11 monosolvents (methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, acetone, acetonitrile, methyl isobutyl ketone, acetate ethyl acetate) (acetone + acetonitrile) binary solvents, has been through gravimetric...
The solubility of N-acetyl-l-leucine in 12 mono organic solvents (methanol, ethanol, n-propanol, 2-propanol, 1-butanol, isobutanol, 2-butanol, methyl acetate, ethyl propyl acetone, and acetonitrile) was determined by the gravimetric method over temperatures ranging from 283.15 to 323.15 K at 0.1 MPa. each experimental solvent increases with increasing temperature. Moreover, is an order magnitude higher alcohol than other solvents, which mainly attributed hydrogen bond formation. In addition,...
p-(Aminomethyl) benzoic acid (PAMBA) is widely used as hemostatic. As reported in the literature, it also plays an important role synthesis of a series organic compounds, such tranexamic acid, cyclohexadiene, and N-carboxyphenylpyrrole derivatives. In this work, solid–liquid equilibrium solubility PAMBA four binary solvents (water + methanol, water ethanol, 1-propanol, 2-propanol) was measured by static method from 288.15 to 328.15 K at atmospheric pressure. The increases with increasing...