Yan Zhang

ORCID: 0000-0001-5959-637X
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About
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Research Areas
  • Luminescence and Fluorescent Materials
  • Molecular Sensors and Ion Detection
  • Advanced biosensing and bioanalysis techniques
  • Nanoplatforms for cancer theranostics
  • Analytical chemistry methods development
  • Microbial Metabolic Engineering and Bioproduction
  • Analytical Chemistry and Chromatography
  • Polydiacetylene-based materials and applications
  • Carbon and Quantum Dots Applications
  • Protein Interaction Studies and Fluorescence Analysis
  • RNA Interference and Gene Delivery
  • Microbial Metabolism and Applications
  • Supramolecular Chemistry and Complexes
  • Liquid Crystal Research Advancements
  • Pharmacological Effects and Assays
  • Water Quality Monitoring and Analysis
  • Pesticide Residue Analysis and Safety
  • Supramolecular Self-Assembly in Materials
  • Nanocomposite Films for Food Packaging
  • Bacterial Genetics and Biotechnology
  • Biosensors and Analytical Detection
  • Synthesis and Properties of Aromatic Compounds
  • Advanced Nanomaterials in Catalysis
  • Electrochemical sensors and biosensors
  • Advanced Chemical Sensor Technologies

Yancheng Institute of Technology
2024

Tianjin University of Science and Technology
2006-2024

Chongqing Public Health Medical Center
2023-2024

Chongqing Normal University
2018-2024

Chongqing Medical University
2009-2024

Tianjin Medical University Cancer Institute and Hospital
2024

Jilin University
2012-2022

Guiyang University
2020

Tianjin Normal University
2019

University of Jinan
2017

Folic acid-functionalized polymer dots with aggregation induced emission features (AIE Pdots), which show high fluorescence efficiency and little toxicity to living cells, possess a good capability for targeted HeLa intracellular imaging.

10.1039/c4py00075g article EN Polymer Chemistry 2014-01-01

An aggregation-induced emission (AIE) molecule, TPA-AN-TPM, with near-infrared was synthesized by coating a disc-like red fluorophore propeller-shaped AIE fluorophore.

10.1039/c4py00764f article EN Polymer Chemistry 2014-01-01

A label-free fluorescence turn-on approach for the selective sensing of Pb2+ based on quaternary ammonium salt 9,10-distyrylanthracene with aggregation-induced emission (AIE) property was developed through Pb2+-induced allosteric G-quadruplex (G4). The method is simple, easy to operate, cost-effective, and provides good sensitivity selectivity.

10.1039/c2ay26202a article EN Analytical Methods 2012-11-21

To investigate the expression of advanced glycation end products (AGEs) and receptor for AGE (RAGEs) in maternal blood, umbilical blood placental tissues women with severe preeclampsia (sPE) as well any association inflammatory processes.The expressions AGEs, RAGE, tumor necrosis factor-alpha (TNF)-α vascular cell adhesion molecule-1 (VCAM)-1 were measured using immunohistochemistry. The levels TNF-α VCAM-1 extracts assessed enzyme-linked immunosorbent assays. Placental mRNA determined by...

10.1159/000448141 article EN Gynecologic and Obstetric Investigation 2016-08-09

Abstract Analagous to a long-ranged rocket equipped with multi-stage engines, luminescent compound consistent emission signals across large range of concentrations from two stages sensitizers can be designed. In this approach, ACQ, aggregation-caused quenching effect sensitizers, would stimulate lanthanide below 10 −4 M and then at higher than −3 M, the “aggregation-induced emission” (AIE) luminophores activated next set for emission. Simultaneously, concentration molecules could monitored...

10.1038/srep09335 article EN cc-by Scientific Reports 2015-03-20

Abstract Hyperspectral imaging technology coupled with chemometric algorithms was investigated to determine soluble solids content (SSC) and firmness in plum. A model of determining SSC plum established optimized. images two varieties “Red” “Green” plums were acquired by hyperspectral acquisition system. Two methods partial least square regression (PLSR) principal components (PCR) employed establish models based on full spectra. The multiple linear (MLR) error back propagation (BP) network...

10.1111/jfpe.13597 article EN Journal of Food Process Engineering 2020-11-23

Cronobacter spp. are opportunistic pathogens, and infections associated with a high mortality rate. In the current study, monoclonal antibodies (mAbs) polyclonal (pAbs) were generated using heat-inactivated C. sakazakii strain ATCC29544 as immunogen. Following assay optimization, an indirect enzyme-linked immunosorbent (ELISA) based on pAbs sandwich ELISA mAbs established for detection of The detected all species assayed, limit (LOD) was 105 cfu/mL. contrast, specific had greater sensitivity...

10.1016/j.lwt.2013.11.028 article EN cc-by-nc-nd LWT 2013-12-03

Near-infrared emissive organic dots with a high fluorescence quantum efficiency (AEE dots) are prepared by using an amphiphilic polymer PSMA and novel small molecule fluorogen (DPPBPA).

10.1039/c5ra04669f article EN RSC Advances 2015-01-01

Cisplatin (DDP), a first-line chemo-drug for cervical cancer therapy, has limited the clinical use due to its high-dose administration and strong side effects. In this study, estrone-targeted PEGylated Liposomal DDP (ES-SSL-DDP) was prepared by thin-film hydration method characterized. ES-SSL-DDP presented spherical structure, with particle size of about 97.3 nm, surface charge -19 mV high encapsulation efficiency 47.7%. showed higher stability lower leakage rate less than 10% at 4°C. vitro...

10.1016/j.ejps.2022.106187 article EN cc-by-nc-nd European Journal of Pharmaceutical Sciences 2022-04-14

Three kinds of crystals two phenothiazine derivatives transformed into similar amorphous powders, in which the short-range π-stacking can be deduced by single-crystal structure.

10.1039/c9ce00568d article EN CrystEngComm 2019-01-01

Herein, a novel on-off-on fluorescent chemosensor for copper (II) ion (Cu2+), iron (III) (Fe3+) and cysteine is developed simply by the nano-precipitation method. The prepared organic dots with AIEgens (AIE dots) are advantageous over other metal ions in detecting Cu2+, Fe3+ high selectivity sensitivity forming agglomerations (on-off). formed AIE Cu2+ redistributed fluorescence was obviously recovered presence of (off-on). This sensor has wide linear range cysteine. detection limits...

10.3390/polym10070786 article EN Polymers 2018-07-17
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