A5022097302- Medical Imaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Anatomy and Medical Technology
- Augmented Reality Applications
- Surgical Simulation and Training
- Radiation Dose and Imaging
- Cardiac Imaging and Diagnostics
- Functional Brain Connectivity Studies
- Radiation Therapy and Dosimetry
- Soft Robotics and Applications
- Advanced biosensing and bioanalysis techniques
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Sparse and Compressive Sensing Techniques
- Analytical Chemistry and Sensors
- Glioma Diagnosis and Treatment
- Biosensors and Analytical Detection
- Radiomics and Machine Learning in Medical Imaging
- Medical Image Segmentation Techniques
- Neural dynamics and brain function
- Cardiac tumors and thrombi
- Advanced Optical Sensing Technologies
- Optical measurement and interference techniques
Universidad Carlos III de Madrid
2013-2018
Hospital General Universitario Gregorio Marañón
2011-2017
Johns Hopkins University
2016-2017
Centro de Investigación Biomédica en Red de Salud Mental
2013
Experimental Medicine and Biology Institute
2013
Universidad de Granada
2011
Intra-operative electron radiation therapy (IOERT) combines surgery and ionizing applied directly to an exposed unresected tumour mass or a post-resection bed. The is collimated conducted by specific applicator docked the linear accelerator. dose distribution in tissues be irradiated organs at risk can planned through pre-operative computed tomography (CT) study. However, surgical retraction of structures resection affecting normal significantly modify patient's geometry. Therefore,...
People differ in their cognitive functioning.This variability has been exhaustively examined at the behavioral, neural and genetic level to uncover mechanisms by which some individuals are more cognitively efficient than others.Studies investigating underpinnings of interindividual differences cognition aim establish a reliable nexus between functional/structural properties given brain network higher order performance.However, these studies have produced inconsistent results, might be partly...
In the last decades accumulated clinical evidence has proven that intra-operative radiation therapy (IORT) is a very valuable technique. spite of that, planning technology not evolved since its conception, being outdated in comparison to current state art other radiotherapy techniques and therefore slowing down adoption IORT. RADIANCE an IORT system, CE FDA certified, developed by consortium companies, hospitals universities overcome such technological backwardness. provides all basic tools...
Intraoperative electron radiation therapy (IOERT) involves irradiation of an unresected tumour or a post-resection bed. The dose distribution is calculated from preoperative computed tomography (CT) study acquired using CT simulator. However, differences between the actual IOERT field and that arise as result patient position, surgical access, resection set-up. imaging may then enable more accurate estimation distribution. In this study, we evaluated three kilovoltage (kV) scanners with...
Purpose Compressed sensing (CS) has been widely applied to prospective cardiac cine MRI. The aim of this work is study the benefits obtained by including motion estimation in CS framework for small-animal retrospective cine. Methods We propose a novel B-spline-based compressed method (SPLICS) that includes and generalizes previous spatiotemporal total variation (ST-TV) methods taking into account between frames. In addition, we assess effect an optimum weighting spatial temporal sparsity...
Image-guided interventions enable the surgeon to display position of instruments and devices with respect patient's imaging studies during surgery by means a tracker device. Optical trackers are commonly chosen for many surgical applications when high accuracy robustness required. OptiTrack is multicamera optical whose number sensors their spatial configuration can be adapted application requirements, making it suitable settings. Nonetheless, no extensive its available. The purpose this...
Low-dose protocols for respiratory gating in cardiothoracic small-animal imaging lead to streak artifacts the images reconstructed with a Feldkamp-Davis-Kress (FDK) method. We propose novel prior- and motion-based reconstruction (PRIMOR) method, which improves prior-based (PBR) by adding penalty function that includes model of motion. The prior image is generated as average all gates, FDK. Motion between gates estimated using nonrigid registration method based on hierarchical B-splines....
Abstract Background A difficulty in computer‐assisted interventions is acquiring the patient's anatomy intraoperatively. Standard modalities have several limitations: low image quality (ultrasound), radiation exposure (computed tomography) or high costs (magnetic resonance imaging). An alternative approach uses a tracked pointer; however, pointer causes tissue deformation and requires sterilizing. Recent proposals, utilizing conoscopic holography device, shown promising results without...
Dynamic contrast enhanced CT can be used to measure perfusion, thus enabling a quantitative assessment of vascular integrity. Conventional dynamic involves the reconstruction sequences 3D images from complete projections acquired at relatively short time intervals. This approach is suitable for spiral scanners but it unfeasible most small-animal cone-beam scanners, as distribution agent changes during acquisition and leads inconsistent projections. We present new algorithm achieve 4D...
Purpose: Extremity cone‐beam CT (CBCT) with an amorphous silicon (aSi) flat‐panel detector (FPD) provides low‐dose volumetric imaging high spatial resolution. We investigate the performance of newer complementary metal‐oxide semiconductor (CMOS) detectors to enhance resolution extremities CBCT ∼0.1 mm, enabling morphological analysis trabecular bone. Quantitative in‐vivo bone microarchitecture could present important advance for osteoporosis and osteoarthritis diagnosis therapy assessment....
Purpose Intraoperative electron radiation therapy ( IOERT ) involves the delivery of a high dose during tumor resection in shorter time than other techniques, thus improving local control tumors. However, linear accelerator device is needed to produce beam safely. Mobile accelerators have been designed as dedicated units that can be moved into operating room and deliver situ . Correct safe key concern when using mobile accelerators. The applicator commonly fixed patient's bed ensure...
Recent progress in X-ray CT is contributing to the advent of new clinical applications. A common challenge for these applications need image reconstruction methods that meet tight constraints radiation dose and geometrical limitations acquisition. The recent developments sparse provide a framework permits obtaining good quality images from drastically reduced signal-to-noise-ratio limited-view data. In this work, we present our contributions field. For dynamic studies (3D+Time), explored...