- Ophthalmology and Eye Disorders
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Intraocular Surgery and Lenses
- Cerebral Venous Sinus Thrombosis
- Pituitary Gland Disorders and Treatments
- Facial Rejuvenation and Surgery Techniques
- Ocular Diseases and Behçet’s Syndrome
- Ocular Surface and Contact Lens
- Facial Trauma and Fracture Management
- Botulinum Toxin and Related Neurological Disorders
- Retinopathy of Prematurity Studies
- Systemic Lupus Erythematosus Research
- Retinal and Optic Conditions
- Sinusitis and nasal conditions
- Traumatic Ocular and Foreign Body Injuries
- Vestibular and auditory disorders
- Liver Disease Diagnosis and Treatment
- Ocular Disorders and Treatments
- Meningioma and schwannoma management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Otitis Media and Relapsing Polychondritis
- Nasolacrimal Duct Obstruction Treatments
Catholic University of Korea
2015-2024
Seoul St. Mary's Hospital
2015-2024
CHA University
2014-2024
Sungshin Women's University
2024
Weatherford College
2022
St. Paul's Hospital
2019
CHA Bundang Medical Center
2014-2016
University of California, Los Angeles
2014-2015
St. Mary's Medical Center
2014
St. Mary's Hospital
2014
Phosphatidylinositol 4,5-bisphosphate (PIP2) is an important cellular effector whose functions include the regulation of ion channels and membrane trafficking. Aberrant PIP2 metabolism has also been implicated in a variety human disease states, e.g., cancer diabetes. Here we report that familial Alzheimer's (FAD)-associated presenilin mutations cause imbalance metabolism. We find transient receptor potential melastatin 7 (TRPM7)-associated Mg2+ -inhibited cation (MIC) channel underlies...
Purpose To evaluate the performance of macular ganglion cell-inner plexiform layer (mGCIPL) measurement with Cirrus high-definition (HD) optical coherence tomography (OCT) for early detection optic chiasmal compression. Methods Forty-six eyes 46 patients compression caused by a pituitary adenoma (PA group), 31 normal tension glaucoma (NTG and 32 participants (control group) were enrolled. The PA group was subdivided into two subgroups, which comprised temporal visual field (VF) defects...
Purpose The outbreak of coronavirus disease 2019 (COVID-19) has caused many children to stay indoors. Increased near work and insufficient outdoor activities are considered important risk factors for myopic progression. This study aimed compare the changes in progression before after COVID-19 treated with low-concentration atropine. Methods records 103 eyes who were atropine eye drops retrospectively reviewed. We classified according concentration children’s age. beginning pre-COVID-19...
AIM: To evaluate the efficacy and safety of three different concentrations diluted atropine for control myopia in Korean children, to assess risk factors associated with rapid progression. METHODS: A total 285 refractive errors within range -6 diopters (D) between 5 14 years age were included. After using 0.01%, or 0.025%, 0.05% atropine, about 1y, changes refraction, axial lengths frequency adverse events analyzed. Logistic regression analyses performed RESULTS: The mean spherical...
Purpose: To report a case of bilateral ophthalmic artery occlusion in rhino-orbito-cerebral mucormycosis.Methods: Reviewed clinical charts, photographs, and fluorescein angiography Results: An 89-year-old man with poorly controlled diabetes developed sudden ptosis, complete ophthalmoplegia the right eye, superior rectus palsy left eye.Brain orbit magnetic resonance imaging showed midbrain infarction mild diffuse sinusitis.On 2nd day hospitalization, visual loss light reflex developed.There...
Postoperative nausea and vomiting (PONV) is one of the most common adverse outcomes after strabismus surgery. The primary outcome this prospective, randomized, double-blind study was to compare incidences or vomiting, patient satisfaction ondansetron ramosetron surgery under general anesthesia. secondary investigate whether number involved extraocular muscles (EOMs) in related PONV.One hundred five patients (aged 18-60 years) undergoing were allocated randomly three groups: placebo,...
Colonoscopic perforations have been managed with exploratory laparotomy, and resulted in some morbidity mortality. Recently, laparoscopic surgery is commonly performed for this purpose. The aim of study was to compare the outcomes several management strategies iatrogenic colonoscopic perforations.We retrospectively reviewed medical records patients who had treated perforation between January 2004 April 2013 at CHA Bundang Medical Center Korea.A total 41 were enrolled. Twenty underwent...
Abstract The Korean Intermittent Exotropia Multicenter Study (KIEMS) was a retrospective, cross-sectional and multicenter study for the investigation of intermittent exotropia involved 65 strabismus specialists from 53 institutions in Korea. Purpose this to present ophthalmologic findings KIEMS. Consecutive patients with ≥ 8 prism diopters (PD) at distance or near fixation were included. Best-corrected visual acuity, cycloplegic refraction data, angles deviation several cardinal positions,...
This study was undertaken to investigate age-dependent and postmenopausal changes in the serum levels of anti-Mullerian hormone (AMH), inhibin B, insulin-like growth factor (IGF)-I, IGF-binding protein-3 (IGFBP-3), follicle-stimulating (FSH), determine which these markers best reflects aging process women. A total 144 women aged 20-59 yr were enrolled this cross-sectional study. Blood samples obtained on cycle day 3 regularly menstruating (n=111), or at random (n=33). Data analyzed with...
The purpose of this study was to identify the correlation skin toxicity and hypertension with clinical benefit in advanced hepatocellular carcinoma (HCC) patients treated sorafenib by analyzing medical records retrospectively.Data from statistically analyzed a treatment response prognosis HCC who had received at Asan Medical Center July 2010 June 2012. This investigated prognostic factors for overall survival between development toxicities hypertension.A total 99 receiving were included...
The aim was to evaluate the characteristic clinical features of posterior microphthalmos.Medical records four patients (eight eyes) between ages three and 31 years with microphthalmos were reviewed retrospectively. Thorough ocular examinations performed, including visual acuity, intraocular pressure, alignment, axial length, cycloplegic refraction, slitlamp biomicroscopy anterior segment fundus spectral-domain optical coherent tomography (SD-OCT).All subjects had presented high hyperopia...
To analyse structural characteristics and perifoveal/peripapillary vasculature by OCT in children with peripapillary hyperreflective ovoid mass-like structures (PHOMS) compare the results those of normal subjects. Forty-five patients (84 eyes) under 18 years old blurry disc margin were evaluated spectral domain-OCT swept course-OCT. Patients divided into four groups, according to presence PHOMS then size existing PHOMS. Eyes visible optic drusen (ODD) not included. Foveal avascular zone...
Purpose: To evaluate the usefulness of an anti-transforming growth factor-β (TGF-β) agent, pirfenidone (PFD) on postoperative inflammation and fibrosis following strabismus surgery in rabbits.Methods: Both eyes 16 New Zealand white rabbits underwent reinsertion superior rectus muscle (SRM). After SRM, PFD-loaded liposomes (0.5 mg/ml) were injected into right eye (PFD group) normal saline-loaded was left (control group), subconjunctivally (0.4 ml). assess inflammatory changes...
<i>Purpose:</i> To study histopathological changes in rabbit conjunctiva after suction ring application. <i>Methods:</i> A was applied to adult albino eyes (n = 30) with a vacuum pressure of 508 mm Hg for 40 s. Three rabbits were sacrificed at 3 h (3-hour group), 6 (6-hour 1 day (1-day days (3-day and 7 (7-day group) the Histopathological examinations included hematoxylin eosin, Alcian blue pH 2.5-periodic acid-Schiff (AB2.5-PAS), 1.0-periodic (AB1.0-PAS) staining....
The aims of this study were to elucidate the detailed anatomy abducens nerve in lateral rectus muscle (LRM) and intramuscular innervation pattern using Sihler staining. In cohort study, 32 eyes 16 cadavers assessed. Dissection was performed from LRM origin its insertion. following distances measured: insertion bifurcation point nerve, entry site superior branch or inferior branch, upper border lower widths main trunk branches. single divided into two branches 37 mm LRM, 22 (68.8%) orbits...
<h3>Objective</h3> To investigate changes in ocular factors according to the binocular disparity three-dimensional (3D) images and age after watching 3D display. <h3>Methods</h3> A total of 38 volunteers were enrolled, they watched a display with 1° or 3° for 30 min at an interval 1 week. The near point accommodation (NPA), convergence (NPC) tear break-up time (tBUT) each subject measured before In addition, meniscus height depth using Visante optical coherence tomography osmolarity was...
To describe clinical features in children diagnosed with posterior polymorphous corneal dystrophy (PPCD) their first or second decade of life.A retrospective study was performed the medical records seven unrelated Korean pediatric patients who were PPCD and followed up for a minimum 3 years. Thorough ocular examinations performed, including best-corrected visual acuity, intraocular pressure, refractive keratometric measurements, slit-lamp biomicroscopy, specular microscopy at all...
Objective To determine (1) how the specific muscle undergoing surgical treatment affects occurrence of oculocardiac reflex (OCR) and oculorespiratory (ORR) (2) whether depth anesthesia influences OCR ORR in patients strabismus surgery with a laryngeal mask airway maintenance spontaneous respiration. Methods The medical records who underwent on lateral rectus (LR) medial (MR) muscles from January 2017 to December were retrospectively reviewed. Results incidence was not significantly different...
Purpose: To report a case of third, fourth, and six cranial nerve palsies with antiphospholipid syndrome (APS).Methods: Medical records 16 year old female diagnosed idiopathic intracranial hypertension (IIH) in primary APS were reviewed.Results: A presented headache diplopia.Ocular examinations revealed marked bilateral disc edema.She was unable to depress, adduct, abduct left eye had limited abduction the right eye.Cerebrospinal fluid normal composition pressure 400 mmH2O.Lupus...
We report a case of multiple myeloma that presented as fluctuating sixth cranial nerve palsy in the absence widespread signs systemic disease.A 63-year-old woman with horizontal diplopia two weeks duration subjectively changed over time.Ocular examination showed palsy.A computed tomography (CT) scan brain multiple, enhancing, soft tissue, mass-like lesions involving left cavernous sinus and apex both petrous bones.Based on bone marrow biopsy hematologic findings, she was diagnosed...
Purpose TO report a pathologically confirmed case of optic nerve metastasis breast carcinoma, which was initially misdiagnosed as retrobulbar neuritis. There have been no reports isolated carcinoma with nonspecific initial fundus and neuroimaging findings. Methods A 51-year-old woman presented decreased visual acuity in her left eye for 15 days. She had undergone modified radical mastectomy 10 years earlier. The funduscopic findings were nonspecific, except slightly enlarged cup-to-disc...