A5079003243- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- MRI in cancer diagnosis
- Radiopharmaceutical Chemistry and Applications
- Cardiac Imaging and Diagnostics
- Advanced biosensing and bioanalysis techniques
- Cancer, Hypoxia, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Thin-Film Transistor Technologies
- Lung Cancer Diagnosis and Treatment
- ZnO doping and properties
- RNA Interference and Gene Delivery
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Thyroid Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Transition Metal Oxide Nanomaterials
- Renal cell carcinoma treatment
- Head and Neck Cancer Studies
- Parathyroid Disorders and Treatments
- Management of metastatic bone disease
Sungkyunkwan University
2016-2025
Samsung Medical Center
2025
Yonsei University
2015-2024
Severance Hospital
2015-2024
Seoul National University
2004-2024
Ulsan National Institute of Science and Technology
2023
University of Illinois Chicago
2021
LG (South Korea)
2019
National Research Foundation of Korea
2016-2017
Government of the Republic of Korea
2016
The efficacy of intracoronary infusion granulocyte colony-stimulating factor (G-CSF) mobilized peripheral blood stem cells (PBSCs) has not been compared between patients with acute (AMI) versus old myocardial infarction (OMI). In addition, the potential risk restenosis associated G-CSF-based cell therapy evaluated in setting drug eluting stent (DES) implantation.We randomly allocated 96 who underwent coronary revascularization DES for culprit lesion into 4 groups. Eighty-two completed...
Aptamers conjugated with quantum dots (QDs) bind to target molecules on the cellular membrane of cancer cells. QDs a carboxyl terminal are three types tumor-targeting aptamer (see picture). Various cell simultaneously targeted QD-TTA1 (605nm, light green), QD-AS1411 (655nm, red), and QD-MUC-1 (705nm, violet). Detailed facts importance specialist readers published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by...
Abstract Background In the course of surveillance gastric cancer recurrence after curative resection, contrast CT scan is used in general. However, new findings from are not always confirmatory for recurrence. this case, we usually use short-term follow up strategy or therapeutic intervention with clinical decision. Recently, fusion Positron Emission Tomography/Computed Tomography (PET/CT) increasing. The purpose study to evaluate efficacy and usefulness PET/CT detecting resection. Methods...
High mobility group box-1 (HMGB1), a proinflammatory cytokine, plays pivotal role in tissue remodeling and angiogenesis, both of which are crucial for the pathogenesis pulmonary arterial hypertension. In this study, we explored relationship between HMGB1 hypertension whether glycyrrhizin, an inhibitor HMGB1, attenuates disease progression animal model induced by monocrotaline sodium (MCT).After inducing through single subcutaneous injection MCT (60 mg/kg) to Sprague-Dawley rats, administered...
Abstract We have demonstrated that photo-thin film transistors (photo-TFTs) fabricated via a simple defect-generating process could achieve fast recovery, high signal to noise (S/N) ratio, and sensitivity. The photo-TFTs are inverted-staggered bottom-gate type indium-gallium-zinc-oxide (IGZO) TFTs using atomic layer deposition (ALD)-derived Al 2 O 3 gate insulators. surfaces of the insulators damaged by ion bombardment during IGZO channel layers sputtering damage results in hysteresis...
Background/Purpose Aptamers are oligonucleotide or peptide molecules that bind to a target molecule with high affinity and specificity. The present study aimed evaluate the specificity applicability for in vivo molecular imaging of an aptamer labeled radioisotope. Methods human epidermal growth factor receptor 2 (HER2/ErbB2) was radiolabeled 18F-fluoride. HER2-positive tumor cell uptake evaluated comparison negative controls by flow cytometry confocal microscopy. Using 18F-labeled...
Process Reward Models (PRMs) have proven effective at enhancing mathematical reasoning for Large Language (LLMs) by leveraging increased inference-time computation. However, they are predominantly trained on data and their generalizability to non-mathematical domains has not been rigorously studied. In response, this work first shows that current PRMs poor performance in other domains. To address limitation, we introduce VersaPRM, a multi-domain PRM synthetic generated using our novel...
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, and treatment outcomes for advanced disease remain suboptimal. Immunotherapy, particularly atezolizumab plus bevacizumab, has shown promise in improving survival. This study aimed to evaluate the prognostic value 18F-fluorocholine positron emission tomography/computed tomography (FCH PET/CT) patients with unresectable HCC undergoing this combination therapy. prospective included 29 treated bevacizumab. All...
Abstract Semiconductor quantum dots (QDs), which have broad absorption with narrow emission spectra, are useful for multiplex imaging. Here, fluorescence derby imaging using dual color QDs conjugated by the AS1411 aptamer (targeting nucleolin) and arginine–glycine–aspartic acid integrin α v β 3 ) in cancer cells is reported. Simultaneous of cellular distribution nucleolin enables easy monitoring separate targets normal healthy cells. These results suggest feasibility a concurrent...
Abstract BACKGROUND: Metabolic activity assessed by 18 F‐fluorodeoxyglocuse‐positron emission tomography ( F‐FDG‐PET) reflects biological aggressiveness and prognoses in various tumors. The authors present a correlation between tumor metabolic clinical outcomes patients with hepatocellular carcinoma (HCC). METHODS: Over 3‐year period (2005‐2008), 135 locally advanced HCC were treated localized concurrent chemoradiotherapy (CCRT; external beam radiotherapy at 45 grays for 5 weeks plus hepatic...
The <sup>18</sup>F-FDG uptake pattern on PET could be an indicator of the prognosis and aggressiveness various tumors, including hepatocellular carcinoma (HCC). Hexokinase, especially hexokinase type II (HKII), plays a critical role in rapidly growing tumors. We established stable cell line overexpressing HKII by transfection full DNA to HCC cells (SNU449) that express low levels investigated how mechanisms, overexpression HKII, are linked tumor proliferation mechanisms. <b>Methods:</b> gene...