A5019297545- Bone and Dental Protein Studies
- Fluoride Effects and Removal
- S100 Proteins and Annexins
- Cancer, Hypoxia, and Metabolism
- Therapeutic Uses of Natural Elements
- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Heavy Metal Exposure and Toxicity
- Cancer therapeutics and mechanisms
- Bee Products Chemical Analysis
- Sesquiterpenes and Asteraceae Studies
- Coffee research and impacts
- Biochemical and biochemical processes
- Plant Toxicity and Pharmacological Properties
- Fermentation and Sensory Analysis
- Alcoholism and Thiamine Deficiency
- Magnesium in Health and Disease
- Family Support in Illness
- Helicobacter pylori-related gastroenterology studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Toxic Organic Pollutants Impact
- Glycogen Storage Diseases and Myoclonus
- Pressure Ulcer Prevention and Management
- Bioactive Compounds and Antitumor Agents
- Psychological and Temporal Perspectives Research
Pomeranian Medical University
2019-2025
University of Szczecin
2016-2022
Eugenol (EU) and isoeugenol (IZO-EU) are naturally occurring compounds known for their strong antibacterial properties, which makes them ideal candidates application as preservatives in cosmetic products. Primarily derived from clove oil, EU demonstrates potent effects against a wide range of microorganisms, including Gram-positive Gram-negative bacteria, well yeast-like fungi such Candida albicans. Their action is mainly connected with ability to disrupt microbial cell membranes inhibit key...
Increasingly popular, recreational diving is a physical activity that takes place under extreme environmental conditions, which include hyperoxia, hyperbaria and exposure to cold water. The effects of these factors on the human body induce increased levels reactive oxygen nitrogen species in divers’ bodies, may modulate damage-associated molecular pattern (DAMPs), their receptors antioxidant response. This study involved 21 divers who descended depth 40 metres. Determinations selected...
Fluoride (F) exposure decreases brain receptor activity and neurotransmitter production. A recent study has shown that chronic fluoride during childhood can affect cognitive function decrease intelligence quotient, but the mechanism of this phenomenon is still incomplete. Extracellular matrix (ECM) its enzymes are one key players neuroplasticity which essential for development. Changes in structure functioning synapses caused, among others, by ECM enzymes. These enzymes, especially...
Burns exceeding 30% of total body surface area (TBSA) result in considerable hypovolemia coupled with the formation and release inflammatory mediators, leading to subsequent systemic effects known as burn shock. Because plasma exudation associated losses large quantities minerals, severe burns can lead nutritional deficiencies consequently disrupt homeostasis metabolism entire body. The study group comprised 62 patients, who were divided into 3 groups according severity burns. Serum samples...
Glioblastoma multiforme (GBM) is a brain tumor with very poor prognosis. For this reason, researchers worldwide study the impact of microenvironment in GBM, such as effect chemokines. In present study, we focus on role chemokine CCL18 and its receptors GBM tumor. We measured expression CCL18, CCR8 PITPNM3 GMB from patients (16 men 12 women) using quantitative real-time polymerase chain reaction. To investigate proliferation migration cells, experiments were performed U-87 MG cells. The...
Depressive disorders are common among young people and can decrease social competences thus the quality of life. There is a relationship between occurrence depressive insomnia. The aim study was to determine prevalence insomnia behavior assess these participants Pol’and’Rock Festival, Kostrzyn, Poland 2019. used Athens Insomnia Scale (AIS) Beck Inventory II (BDI-II). group consisted 923 people, with majority women (n = 500; 54.2%). A total 297 persons (32.2%) reported varying severity...
Breast milk has the most suitable composition for proper development in first year of a child’s life. However, it is often replaced with artificial milk. The aim study was to analyze essential elements: Na, K, Ca, P, Mg, Fe, Zn, Cu, and Mn as well toxic Ni, Pb, Sr, Li, In 18 formulas available Poland. daily supply also estimated. performed by Inductively Coupled Plasma Optical Emission Spectrometry method. results showed presence all elements tested, but content P significantly differed from...
Glioblastoma remains one of the most treatment-resistant and malignant human cancers. Given documented harmful effects fluoride on developing central nervous system rising incidence brain tumors, especially among children, it is pertinent to explore role environmental toxins, including compounds, in context cancer. This study represents first investigation into influence mechanisms related invasiveness glioblastoma cells. We examined sodium (NaF) exposure migratory invasive abilities U-87...
Anxiety is a subjective feeling of fear in response to stressful or threatening situations. Chronic diseases (such as chronic kidney disease) the state after transplantation are such situations and they may result decreased quality life. The main aim this research was evaluate if proteins IL-8, RANTES, MIG, MCP-1, IP-10, IL-12p70 could be indicators higher levels anxiety life chronically ill women. assessment conducted using STAI SF-36 questionnaires with measurement listed from patient’s...
Multidrug resistance (MDR), having a multifactorial nature, is one of the major clinical problems causing failure anticancer therapy. The aim this study was to examine antitumour effects selected pyridinium salts, 1-methyl-3-nitropyridine chloride (MNP) and 3,3,6,6,10-pentamethyl-3,4,6,7-tetrahydro-[1,8(2H,5H)-dion]acridine (MDION), on sensitive leukaemia HL60 cells resistant topoisomerase II-defective HL60/MX2 cells. Cell growth determined by MTT test. Intracellular ROS level measured with...
The exposure of humans to fluorine is connected with its presence in the air, food and water. It well known that fluorides even at a low concentration but long time accumulate body lead numerous metabolic disorders. Fluoride recognised as factor modulating energy metabolism cells. This interaction particular importance muscle cells, which are cells high activity related glucose glycogen. In someone suffering from chronic fluoride poisoning, frequent symptoms fatigue not relieved by extra...
The ideal immunosuppressive regimen should provide for excellent immunosuppression with no side effects. Yet, current therapy regimens commonly used in clinical applications fail to meet this criterion. One of the complications caused by drugs is mineralization disorders hard tissues. In study, we evaluated effects three therapies after transplantation on levels potassium, iron, chromium, zinc, aluminum, sodium and molybdenum bones teeth female rats their offspring. study was conducted 32...
A research on the total antioxidant capacity, phenolic content and antimicrobial properties against Staphylococcus aureus, Escherichia coli Candida albicans of grape vinegars was conducted. The material consisted made from different wine varieties grown in Poland. study used white varieties: Solaris, Johanniter Souvignier gris, as well red Prior Cabernet cortis. For each variety, two variants were prepared: with without addition sugar fermentation process. capacity determined by...
The healing properties of hemp agrimony (Eupatorium cannabinum L.) have been already described in the seventeenth-century Polish medical herbaria. These historical descriptions also pointed to their potential anticancer activity. Contemporary literature data confirm presence many bioactive compounds agrimony, but there are few confirming anti-cancer properties. Phytotherapy is used as a form natural treatment or supporting conventional methods therapy diseases. Supplementation with herbal...
IntroductionFluorine (F) is an element that belongs to the group of halogens. Small amounts fluoride are necessary for proper development bones and teeth. However, increased intake fluorine continuous exposure has negative effects on human organism. Some recent works have shown affects many metabolic pathways can theoretically be involved in invasive potential types cancers, including brain neoplasms. In light studies, influence invasiveness cancer cells seems highly probable but practically...