A5064222199- Liver Disease Diagnosis and Treatment
- Traditional Chinese Medicine Analysis
- Sirtuins and Resveratrol in Medicine
- Biochemical effects in animals
- Liver physiology and pathology
- Drug-Induced Hepatotoxicity and Protection
- Natural product bioactivities and synthesis
- Neurological Disease Mechanisms and Treatments
- Diet, Metabolism, and Disease
- Digestive system and related health
- Chromatography in Natural Products
- Mechanisms of cancer metastasis
- Phytochemical and Pharmacological Studies
- Plant-based Medicinal Research
- Alcohol Consumption and Health Effects
Zhejiang Chinese Medical University
2021-2024
Shanxi University of Traditional Chinese Medicine
2019
Cornus officinalis, a medicinal and edible plant known for its liver-nourishing properties, has shown promise in inhibiting the activation of hepatic stellate cells (HSCs), crucial indicators fibrosis, especially when processed by high pressure wine steaming (HPWS). Herein, this study aims to investigate regulatory effects cornus both raw HPWS forms, on inflammation apoptosis liver fibrosis their underlying mechanisms. In vivo models were established subcutaneous injection CCl4, while vitro...
In Chinese medicine, the effect of promoting blood circulation and removing stasis could be enhanced after Chuanxiong Rhizoma is processed by wine. However, relevant mechanism remains unclear. this manuscript, a rapid sensitive quantification method employing ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was established validated to simultaneously determine butylidenephthalide, ligustilide, senkyunolide A ferulic acid in rat plasma oral administration raw...
Cornus officinalis, a kind of edible herbal medicine, has been widely used in the protection liver and kidney due to its medicinal nutritional effect. Its anti-inflammatory, anti-tumor, anti-oxidant activities can be enhanced by wine-steamed (WS) processing. Based on activations hepatic stellate cells-T6 (HSC-T6) HK-2, our study single-factor plus orthogonal design investigate anti-fibrosis C. officinalis processed with steamed (S), high-pressure (HPS), WS, (HPWS), wine-dipped (WD),...
According to the ancient documents and Chinese herbal medicine processing experience, Chuanxiong Rhizoma was usually processed with yellow rice wine improve efficacy. However, relevant mechanisms are still unclear so far. In this study, a validated ultrahigh-performance liquid chromatography tandem mass spectrometry method used compare pharmacokinetics of four representative components in middle cerebral artery occlusion rats after oral administration raw wine-processed Rhizoma. The...