Zemene Tigabu

ORCID: 0000-0001-6040-032X
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About
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Research Areas
  • Global Maternal and Child Health
  • Child Nutrition and Water Access
  • Vaccine Coverage and Hesitancy
  • Streptococcal Infections and Treatments
  • Child and Adolescent Health
  • Neonatal and Maternal Infections
  • Healthcare Systems and Reforms
  • Neonatal Respiratory Health Research
  • Infective Endocarditis Diagnosis and Management
  • Healthcare Policy and Management
  • Pneumonia and Respiratory Infections
  • Sepsis Diagnosis and Treatment
  • Infant Development and Preterm Care
  • Bacterial Infections and Vaccines
  • Maternal and Neonatal Healthcare
  • Antibiotic Use and Resistance
  • Antimicrobial Resistance in Staphylococcus
  • Viral gastroenteritis research and epidemiology
  • HIV/AIDS Research and Interventions
  • Neuroscience of respiration and sleep
  • Tuberculosis Research and Epidemiology
  • Congenital Diaphragmatic Hernia Studies
  • Viral Infections and Immunology Research
  • Animal Disease Management and Epidemiology
  • Rabies epidemiology and control

University of Gondar
2014-2024

St. Paul's Hospital Millennium Medical College
2020

University of Guam
2020

Neonatal deaths now account for 47% of all in children younger than 5 years globally. More a third newborn are due to preterm birth complications, which is the leading cause death. Understanding causes and factors contributing neonatal needed identify interventions that will reduce mortality. We aimed establish major mortality infants first 28 days life Ethiopia.We did prospective, cross-sectional, observational study five hospitals Ethiopia. Study participants were born at 37 gestational...

10.1016/s2214-109x(19)30220-7 article EN cc-by The Lancet Global Health 2019-07-11

The neonatal period is a highly vulnerable time for an infant completing many of the physiologic adjustments required life outside uterus. As result, there are high rates morbidity and mortality. three major causes mortality in developing countries include prematurity, infection, perinatal asphyxia. aim this study was to identify patterns admission factors associated with among neonates admitted at Neonatal Intensive Care Unit (NICU) University Gondar Hospital.A retrospective cross-sectional...

10.2147/phmt.s130309 article EN cc-by-nc Pediatric Health Medicine and Therapeutics 2017-05-01

Abstract Introduction: Malnutrition is one of the leading causes morbidity and mortality in children under age five developing countries. Ethiopia being these countries malnutrition an important public health problem, however little information available on risk factors for severe acute malnutrition. Objective: To identify determine five. Methods: Matched case-control study design was applied. The cases were 102 severely malnourished controls (n=102) recruited concurrently from...

10.4314/ejhd.v22i1.10058 article EN Ethiopian Journal of Health Development 2008-08-27

Despite the enormous benefits of family planning services, contraceptive utilization still remains low in Sub-Saharan Africa. There is regional variation modern Ethiopia. Therefore, this study was aimed to determine prevalence and determinants Dabat demographic health surveillance system site, northwest A re-census carried out Health Demographic Surveillance System (HDSS) site from October December 2014. Data 8271 married women collected used. The outcome variable current any methods whereas...

10.1186/s12905-018-0611-3 article EN cc-by BMC Women s Health 2018-07-03

With nearly 15 million annual preterm births globally, birth is the most common cause of neonatal death. Forty to 60 % deaths are directly or indirectly associated with mortality. As countries aim meet Sustainable Development Goals reduce mortality, significant reductions in mortality needed. This study aims identify causes illness and their contribution low-resource settings. article will describe methods used undertake study.This a prospective, multi-centre, descriptive clinical study....

10.1186/s12978-018-0555-y article EN cc-by Reproductive Health 2018-06-27

Maternal Streptococcus agalactiae (Group B Streptococcus, GBS) colonization rates and its antibiotic resistance patterns provide important information useful in guiding prevention strategies. There is a paucity of evidence about GBS the Amhara National Regional State, Ethiopia. To determine prevalence, associated risk factors, antibiotics including inducible clindamycin among Ethiopian pregnant women. A prospective cross-sectional study was conducted from 1st December 2016 to 30th November...

10.1186/s12941-019-0303-3 article EN cc-by Annals of Clinical Microbiology and Antimicrobials 2019-01-19

Abstract Background Maternal and child health (MCH) care utilization often vary with geographic location. We analyzed the distribution determinants of four or more antenatal visits, facility delivery, immunization, for common childhood illnesses across Ethiopian regions. Methods A cross-sectional community-based study was employed two-staged stratified cluster sampling in 46 districts Ethiopia. total 6321 women (13–49 years) 3110 children below age 5 years residing 5714 households were...

10.1186/s12939-019-1079-y article EN cc-by International Journal for Equity in Health 2019-11-12

BackgroundPneumonia caused by Streptococcus pneumoniae is the leading cause of death among children in Ethiopia. S. nasopharyngeal carriage can result endogenous infections and bacterial spread community. drug resistance rapidly increasing worldwide. The aim study was to assess antimicrobial susceptibility pattern pediatric outpatients.MethodsA cross-sectional conducted on aged ≤10 years from February May 2012. Data potential risk factors were gathered using an interview-based questionnaire....

10.1016/j.pedneo.2013.03.017 article EN publisher-specific-oa Pediatrics & Neonatology 2013-05-14

Without improving the survival of newborns, meaningful reduction in under-five mortality is difficult. Most neonatal deaths are preventable when appropriate and timely care sought. In Ethiopia, there lack evidence on type contribution delays treatment seeking to deaths. A community based social autopsy (SA) 39 was conducted from March 16 24, 2016 Dabat Health Demographic Surveillance System (HDSS) northwest Ethiopia. The result linked with verbal (VA) information completed for each as part...

10.1186/s12887-017-0967-9 article EN cc-by BMC Pediatrics 2017-12-01

Uncertainty about the causes of neonatal deaths impedes achieving global health targets to reduce mortality. Complete diagnostic autopsy (CDA) is gold standard determine cause death. However, it often difficult perform in high-burden, low-income settings. Validations more feasible methods death are needed. This prospective, multi-center study Ethiopia assessed validity minimally invasive tissue sampling (MITS) approach contribute preterm neonates compared CDA. The MITS and CDA 105 cases were...

10.1177/2333794x20953263 article EN cc-by-nc Global Pediatric Health 2020-01-01

Background: Neonatal sepsis is the third leading cause of neonatal mortality, behind prematurity and intrapartum-related complications. The main objectives this study are to assess proportion in preterm newborns identify etiologic agents their antibiotic sensitivity patterns. Methods: A longitudinal observational was done from July 2016 May 2018. Whenever clinical diagnosis made, blood cultures susceptibility tests were done. Result: We did 690 cultures, 255 (36.9%) showing bacterial growth....

10.1177/2333794x20953318 article EN cc-by-nc Global Pediatric Health 2020-01-01

Objective We assessed whether geographic distance and difference in altitude between home to health facility household socioeconomic status were associated with utilisation of maternal child services rural Ethiopia. Design Household surveys conducted from December 2018 February 2019. Setting Forty-six districts the Ethiopian regions: Amhara, Oromia, Tigray Southern Nations, Nationalities, Peoples. Participants A total 11 877 women aged 13–49 years 5786 children 2–59 months included. Outcome...

10.1136/bmjopen-2020-042095 article EN cc-by BMJ Open 2021-02-01

Ethiopia has fairly good coverage but very low utilization of health care services. Emergency medical services require fast, correct and curious to clients as they present with acute problems. In Gondar in particular, the quality emergency not been studied. The main aim this study was assess disease profile patients' satisfaction University Referral Hospital (GURH). A facility based cross-sectional conducted among patients visiting GURH for care. Ethical clearance obtained from Institutional...

10.1186/1471-227x-14-2 article EN cc-by BMC Emergency Medicine 2014-01-23

Introduction: childhood tuberculosis (TB) treatment is becoming a major challenge in the TB control efforts of Ethiopian health system. This study assessed management, and outcomes among children who completed anti-TB Northwest Ethiopia.

10.11604/pamj.2017.27.25.10120 article EN cc-by Pan African Medical Journal 2017-01-01

Abstract Group B Streptococcus (GBS) vertical transmission causes fetal and neonatal colonization diseases. However, there is scarcity of data in low-income countries including Ethiopia. We conducted a cross-sectional study on 98 GBS positive mothers, their newborns to find proportion transmission. was identified from swabs by using recommended methods at birth confirmed the culture body surface within 30 minutes following birth. positivity among swabbed specimens collected for other...

10.1038/s41598-020-60447-y article EN cc-by Scientific Reports 2020-02-26

. In low-income countries, preterm nutrition is often inadequately addressed. The aim of the study was to assess patterns feeding and associated clinical outcomes neonates admitted neonatal intensive care units in Ethiopia.

10.1177/2333794x20937851 article EN Global Pediatric Health 2020-01-01

Ethiopia has a high acute rheumatic fever (ARF) and heart disease (RHD) prevalence, to our knowledge, there are no data on the status of secondary prevention in children with RHD. This study describes RHD prevention.

10.1186/s12872-022-02473-4 article EN cc-by BMC Cardiovascular Disorders 2022-02-02

even though there is a significant decline in neonatal mortality globally, it remained unacceptably high Ethiopia. The estimated experience of danger signs affects the outcome more than perceived knowledge. main aim this study was to estimate mothers on and its associated factors Northwest Ethiopia.a community-based cross-sectional conducted from April 6-16, 2019. All women who have delivered live birth past six months three districts Ethiopia were source populations. A total 2424 selected...

10.11604/pamj.2022.41.83.32176 article EN PubMed 2022-01-01

Streptococcus agalctiae (Group B Streptococcus, GBS) is a perinatal pathogen and leading cause of neonatal infections worldwide. Serotype, sequence type, clonality, antibiotic resistance genes surface protein profiles GBS are scarce in Ethiopia, reason that this study was planned to investigate. .Sixteen colonizing isolates obtained from recto-vaginal swabs pregnant women body surfaces newborns were further analyzed. Minimum inhibitory concentration (MIC) test, whole genome (WGS) methods...

10.1186/s12879-020-4776-7 article EN cc-by BMC Infectious Diseases 2020-01-13

Background: Globally, rotavirus (RV) A (RVA) is the most common cause of severe and sometimes fatal diarrhea in young children. It also major acute gastroenteritis among children Ethiopia. Currently, WHO has prequalified four RVA vaccines for universal childhood immunization. Ethiopia introduced monovalent Rotarix vaccine into its national immunization program 2013. Since then, only a few studies on burden genotype distribution infection post-vaccine introduction have been conducted (mostly...

10.3390/vaccines12080866 article EN cc-by Vaccines 2024-08-01

Community acquired bacterial meningitis (CABM) is responsible for high mortality and disabling sequelae. Introduction of pneumococcal conjugate vaccine (PCV-10) haemophilus influenzeatype b (Hib) has changed the epidemiological clinical features patients presenting with CABM as it shown in different literatures over last decade. The aim this study was to assess epidemiologic outcomes after introduction PCV-10 Gondar University Hospital (GUH).This a retrospective among children between 2...

10.11604/pamj.2018.31.193.10254 article EN cc-by Pan African Medical Journal 2018-01-01

Group B Streptococcus (GBS) that asymptomatically colonizing the recto-vaginal area of women is most important cause neonatal colonization. There paucity evidence about newborn colonization with GBS in Ethiopia. Thus, this study was aimed to determine prevalence GBS, antibiotic susceptibility patterns isolates and associated risk factors at University Gondar Referral Hospital Northwest Ethiopia A prospective cross sectional conducted from December 2016 November 2017. total 1,155 swabs nasal,...

10.1186/s12887-018-1350-1 article EN cc-by BMC Pediatrics 2018-11-30

Childhood illnesses, such as acute respiratory illness, fever, and diarrhoea, continue to be public health problems in low-income countries. Detecting spatial variations of common childhood illnesses service utilisation is essential for identifying inequities call targeted actions. This study aimed assess the geographical distribution associated factors across Ethiopia based on 2016 Demographic Health Survey.The sample was selected using a two-stage stratified sampling process. A total...

10.1371/journal.pone.0281606 article EN cc-by PLoS ONE 2023-03-10

Enteroviruses (EVs) and human parechoviruses (HPeVs) infections are associated with various forms of disease, including gastroenteritis. As information on the molecular epidemiology these viruses is limited in Ethiopia, genetic diversity EV HPeV was investigated Northwestern part country. Of total 450 stool samples obtained from infants young children diarrhea, 157 (34.9%) were positive for 49 (10.9%) RNA when tested by real-time reverse transcription polymerase chain reaction. Genotyping...

10.1002/jmv.25765 article EN Journal of Medical Virology 2020-03-14
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