- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Ion channel regulation and function
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Medication Adherence and Compliance
- ECG Monitoring and Analysis
- Cardiac Valve Diseases and Treatments
- Diabetes Treatment and Management
- Pericarditis and Cardiac Tamponade
- Streptococcal Infections and Treatments
- Health and Conflict Studies
- Bone health and osteoporosis research
- Diabetes and associated disorders
- HIV/AIDS oral health manifestations
- Analog and Mixed-Signal Circuit Design
- Diverticular Disease and Complications
- Cardiac tumors and thrombi
Hadassah Medical Center
2005-2024
Hebrew University of Jerusalem
2004-2024
Hadassah Academic College
2003-2023
Sunnybrook Health Science Centre
2016-2019
University of Toronto
2016-2019
Istituti Clinici Scientifici Maugeri
2017
Health Sciences Centre
2017
Toronto Public Health
2015
Background Low serum albumin is common in patients with chronic heart failure (HF). Hypothesis Albumin may have an impact on clinical outcome HF. We evaluated the effect of levels a real‐world cohort Methods All HF at health maintenance organization were followed for cardiac‐related hospitalizations and death. Results A total 5779 included study; mean follow‐up was 576 days; median 4.0 g/dL (interquartile range 3.7‐4.2), 12% had hypoalbuminemia (albumin<3.5 g/dL). associated increasing...
We investigated an atypical form of limb-girdle muscular dystrophy type R3 (LGMDR3) associated with a homozygous synonymous variant in SGCA that significantly expands the recognized clinical phenotype to include prominent cardiac involvement. While LGMDR3, caused by pathogenic variants SGCA, typically presents as progressive muscle weakness relatively limited manifestations, individuals our study developed substantial left ventricular dysfunction, arrhythmias, and even life-threatening...
Lead perforation is a rare, well-known complication of cardiac implantable electronic device (CIED) implants, whose management mostly not evidence-based. Main strategies include conservative approach based on clinical and lead function follow-up vs. routine invasive revision approach. This study compared the complications both by composite endpoint, including recurrent perforation-related symptoms, pericardial effusion (PEf), dysfunction, infection during 12 month follow-up.Multicentre...
Confirming the presence and participation of concealed nodo-ventricular (cNV) or His-ventricular (cHV) pathways in tachyarrhythmias is challenging. We describe novel observations to aid diagnosing cNV cHV pathways.We present 7 cases pathway-mediated arrhythmias focus on several laboratory observations: (1) differential ventricular overdrive pacing (VOD) from base versus apex, (2) response His refractory premature complexes, (3) paradoxical atriohisian (shorter interval during tachycardia...
Remote magnetic navigation (RMN) is an alternative to manual catheter control (MCC) radiofrequency ablation of right ventricular outflow tract (RVOT) arrhythmias. The data support RMN approach limited. We aimed investigate the clinical and procedural outcomes in a cohort patients undergoing RVOT premature complex/ventricular tachycardia (PVCs/VT) procedures using vs. MCC. Data was collected from two centres. Eighty-nine consecutive PVCs/VT were performed 75 patients; RMN: 42 MCC: 47...
Heart failure (HF) is associated with considerable mortality. The electrocardiographic frontal QRS-T angle a simple parameter to measure, reflects changes in the direction of repolarization sequence and predicts outcome patients HF. Data regarding temporal HF its impact on limited.To evaluate effect survival HF.Baseline follow-up were calculated from QRS T axis 12-lead surface electrocardiogram. Patients followed for survival.2,929 evaluated. Median interval between baseline ECG was 895...
Background The cardiac ryanodine receptor type 2 (RyR2) is a large homotetramer, located in the sarcoplasmic reticulum (SR), which releases Ca2+ from SR during systole. molecular mechanism underlying sensing and gating of RyR2 channel health disease only partially elucidated. Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT1) most prevalent syndrome caused by mutations. Methods Results This study involves investigation family with 4 cases ventricular fibrillation sudden death...