A5063383003- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Sex work and related issues
- HIV/AIDS drug development and treatment
- LGBTQ Health, Identity, and Policy
- Viral-associated cancers and disorders
- Minimally Invasive Surgical Techniques
- Sexuality, Behavior, and Technology
- Herpesvirus Infections and Treatments
- HIV-related health complications and treatments
- Genital Health and Disease
- Intimate Partner and Family Violence
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Gallbladder and Bile Duct Disorders
- Public Health Policies and Education
- Reproductive Health and Technologies
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- African Sexualities and LGBTQ+ Issues
- Racial and Ethnic Identity Research
- Parvovirus B19 Infection Studies
- Reproductive tract infections research
University of Michigan–Ann Arbor
2018-2024
Emory University
2015-2018
University of Washington
2005-2017
Korea Advertising Society
2016
Cecil College
2016
Austro Control (Austria)
2016
Friedrich-Loeffler-Institut
2012-2015
Makerere University
2013
The Royal Melbourne Hospital
2012
The University of Melbourne
2012
Genital HIV-1 RNA quantity predicts risk of heterosexual transmission independently plasma concentration.
Pre-exposure prophylaxis (PrEP) is a key HIV prevention technology, and pillar of comprehensive approach for men who have sex with (MSM). Because there been no national data to characterize trends in the PrEP continuum United States, overall demographic groups MSM, we aimed describe extent which awareness, willingness use changed over time, specific MSM critical (e.g. Black Hispanic younger rural areas without health coverage).
Background: Daily oral antiretroviral preexposure prophylaxis (PrEP) is a promising strategy for prevention of HIV-1 acquisition. Three clinical trials demonstrated PrEP efficacy; however, two among women did not find protection against HIV-1. One hypothesis proposed these divergent results that efficacy may be reduced in populations with higher incidence. Methods: Using data from the Partners Study, randomized, placebo-controlled trial daily tenofovir (TDF) and emtricitabine/tenofovir...
Background and objectives: Heterosexual HIV-1–serodiscordant couples are increasingly recognized as an important source of new HIV-1 infections in sub-Saharan Africa. A simple risk assessment tool could be useful for identifying at highest transmission. Methods: Using data from 3 prospective studies 7 African countries standard methods development clinical prediction rules, the authors derived validated a scoring developed multivariate modeling composed key predictors that measured research...
Background: Men who have sex with men (MSM) are disproportionately affected by human immunodeficiency virus (HIV) and there is evidence that this population participating in increasingly risky sexual behavior. These changes occurring the context of new modes online social interaction—many MSM now report first meeting their partners on Internet. Better monitoring key behavioral indicators among requires use surveillance strategies capitalize these interaction. Therefore, we developed an...
Natural orifice transluminal endoscopic surgery (NOTES) within the peritoneal cavity is rapidly evolving, using transgastric, transcolonic, or transvaginal access. There little experience with transesophageal NOTES access to mediastinum. This prospective long-term animal survival study was performed explore feasibility and safety of intrathoracic procedures including minor surgery.Nine pigs were used for acute (n = 2) up 6-week studies 7), followed by autopsy histological investigation. The...
Background Characterization of viruses in HIV-1 transmission pairs will help identify biological determinants infectiousness and evaluate candidate interventions to reduce transmission. Although sequencing is frequently used substantiate linkage between newly infected individuals their sexual partners epidemiologic forensic studies, viral seldom applied prevention trials. The Partners Prevention HSV/HIV Transmission Study (ClinicalTrials.gov #NCT00194519) was a prospective randomized...
Background Host genetic factors may be important determinants of HIV-1 sexual acquisition. We performed a genome-wide association study (GWAS) for host variants modifying acquisition and viral control in the context cohort African serodiscordant heterosexual couples. To minimize misclassification risk, we quantified exposure, using data including plasma concentrations, gender, condom use. Methods matched couples without seroconversion to those with by exposure risk. Logistic regression...
Abstract Background Stigmatization may prompt gay, bisexual, queer and other men who have sex with (GBQMSM) to avoid or delay HIV testing. There has been little attention GBQMSMs’ perspectives about how stigma influence their decisions whether, where, often get tested for HIV. Methods We conducted nine focus groups 64 adult GBQMSM in Metropolitan Detroit, including HIV-negative people living (PLWH). Data were thematically analyzed deductively inductively three rounds. Results Three themes...
Background The Partners HSV-2/HIV-1 Transmission Study (Partners Study) is a phase III, placebo-controlled trial of daily acyclovir for genital herpes (HSV-2) suppression among HIV-1/HSV-2 co-infected persons to reduce HIV-1 transmission their susceptible partners, which requires recruitment serodiscordant heterosexual couples. We describe the baseline characteristics this cohort. Methods couples, in infected partner was HSV-2 seropositive, had CD4 count ≥250 cells/mcL and not on...
Background. A heightened proinflammatory state has been hypothesized to enhance human immunodeficiency virus type 1 (HIV-1) transmission – both susceptibility of HIV-1-exposed persons and infectiousness HIV-1-infected persons. Methods. Using prospective data from heterosexual African couples with HIV-1 serodiscordance, we conducted a nested case-control analysis assess the relationship between cytokine concentrations risk acquisition. Case (n = 120) were initially serodiscordant in which was...
ABSTRACT Background and Aims Sexual minority (SM) populations experience higher rates of substance use disorder (SUD) associated with increased sexual orientation‐related stress. Social support may moderate the impact stress on SUD among SM adults. This study assessed associations between social DSM‐5 by sex identity. Design Cross‐sectional using data from 2012–13 National Epidemiologic Survey Alcohol Related Conditions (NESARC‐III). Setting participants A nationally representative...
Transgender youth are at high risk for human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs), but their rates of screening unknown. This study sought to quantify HIV STI testing levels examine variations in across three categories gender identity: transgender men, women, nonbinary individuals.
Purpose: To understand the relationships between stigma, resilience, and health care use among transgender other gender diverse youth (TGDY). Methods: Data include a national sample of 171 TGDY (ages 15-24). Previously developed Gender Minority Stress Theory scales were used to measure experiences stigma resilience. Health included two outcomes: difficulty accessing medical affirmation service (e.g., hormones surgery). Principal components analysis (PCA) was reduce data. Logistic regression...
The association between mild routine exercise and glucose homeostasis, insulin dynamics, risk factors for coronary artery disease was investigated in obese adolescent males. Subjects (n = 7; mean +/- SD age 13.3 1.4 yr) were tested before after 15 wk of supervised intensity exercise. Serum (GLU), (IN), C-peptide (CP) measured response to a mixed meal the period. Weight, body composition, peak oxygen uptake (peak VO2), resting blood pressure (BP), lipid levels also assessed pre-...
See also: Commentaire de travail A. Fritscher-Ravens et al., pp. 925Endoscopy 2008; 40(11): 1059-1059DOI: 10.1055/s-0032-1306889