A5071059098- Neuroscience and Neuropharmacology Research
- Amino Acid Enzymes and Metabolism
- Molecular Sensors and Ion Detection
- Circadian rhythm and melatonin
- Antioxidant Activity and Oxidative Stress
- Neuroinflammation and Neurodegeneration Mechanisms
- Medicinal Plants and Bioactive Compounds
- Biological and pharmacological studies of plants
- Phytochemical Studies and Bioactivities
- Phytochemical and Pharmacological Studies
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Polysaccharides and Plant Cell Walls
- Genetics, Aging, and Longevity in Model Organisms
- Essential Oils and Antimicrobial Activity
Affiliated Hospital of Southwest Medical University
2023-2024
Southwest Medical University
2023-2024
Dendrobium nobile is a traditional Chinese herb with anti-inflammatory, antioxidant, and neuroprotective properties. However, its antiaging effects are unclear. Herein, we studied the aging-related functions mechanism of action alcohol extract (DnAE) in model organism Caenorhabditis elegans. The results indicated that 1 mg/mL DnAE slowed lipofuscin accumulation, decreased levels reactive oxygen species, elevated superoxide dismutase activity, enhanced oxidative heat stress resistance,...
Vaccination is the most effective way to prevent coronavirus disease 2019 (COVID-19). However, it often less protective and does not significantly increase antibody levels, especially in individuals with impaired immune systems. Nevertheless, immunocompetence can be enhanced using a natural immunomodulator, such as Dendrobium officinale aqueous extract (DoAE).
A new naphthyl-coumarin-based probe was developed for selective fluorescent recognition of the aromatic amino acids including phenylalanine (Phe) and tyrosine (Tyr). The racemic used first time to determine enantiomeric excess Phe Tyr. Mechanistic studies indicated that response toward composition might be attributed weak interaction-driven aggregation imines generated from reaction with acid enantiomers in specific polar solvent.
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