A5033777282- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Natural Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Natural product bioactivities and synthesis
- Retinal Development and Disorders
- Phytochemistry and Biological Activities
- Glaucoma and retinal disorders
- Reproductive Biology and Fertility
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Plant Physiology and Cultivation Studies
- Plant-based Medicinal Research
- Adenosine and Purinergic Signaling
- Drug-Induced Hepatotoxicity and Protection
- Ginseng Biological Effects and Applications
- Adipose Tissue and Metabolism
- Renal and related cancers
- Chromatography in Natural Products
- Flavonoids in Medical Research
- Pluripotent Stem Cells Research
- Soil Carbon and Nitrogen Dynamics
- Gut microbiota and health
- Cytomegalovirus and herpesvirus research
- Prenatal Screening and Diagnostics
- Berberine and alkaloids research
Chengdu University of Traditional Chinese Medicine
2016-2025
Henan Institute of Science and Technology
2020-2025
Sun Yat-sen University
2008-2024
Central South University
2020-2024
Southwest Medical University
2024
Jinan University
2016-2024
Hunan Normal University
2024
Reproductive & Genetic Hospital CITIC-Xiangya
2021-2024
Sun Yat-sen Memorial Hospital
2018-2024
Southern Medical University
2022-2024
CC-Cruiser is an artificial intelligence (AI) platform developed for diagnosing childhood cataracts and providing risk stratification treatment recommendations. The high accuracy of was previously validated using specific datasets. objective this study to compare the diagnostic efficacy decision-making capacity between ophthalmologists in real-world clinical settings.This multicentre randomized controlled trial performed five ophthalmic clinics different areas across China. Pediatric...
Phlorizin exists in a number of fruits and foods exhibits many bioactivities. The mechanism its antidiabetic effect has been known as it can competitively inhibit sodium-glucose symporters (SGLTs). However, phlorizin wide range two-phase metabolism systemic circulation shows poor oral bioavailability. An alternative may involve gut microbiota intestine. Sixteen obese mice with type 2 diabetes (db/db) eight age-matched control (db/+) were divided into three groups: diabetic group treated (DMT...
As a subclass of the biopharmaceutical classification system (BCS) class II, basic drugs (BCS IIB) exhibit pH-dependent solubility and tend to generate supersaturation in gastrointestinal tract, leading less qualified vitro-in vivo correlation (IVIVC). This study aims develop physiologically based multi-cup dissolution approach improve evaluation for higher quality IVIVC preliminarily explores molecular mechanism precipitation ketoconazole affected by Polyvinylpyrrolidone-vinyl acetate...
Crop production is strongly impacted by soil nitrogen supply, which regulated micro-food webs consisting of nematodes, protists, fungi and bacteria. However, responses to fertilization at the aggregate scale their relationships with supply crop yield remain unclear. To address these knowledge gaps, we investigated soils subjected typical treatments in a long-term field experiment, included: no fertilizer control (CK); synthetic fertilizers (NPK); partial replacement pig slurry (OMNPK) or...
CD26 is a leukocyte-activation antigen that expressed on T lymphocytes and macrophages possesses dipeptidyl peptidase IV (DPPIV) activity, whose natural substrates have not been identified yet. CXC chemokines, stromal cell-derived factor 1alpha (SDF-1alpha) 1beta (SDF-1beta), sharing the receptor CXCR-4, are highly efficacious chemoattractants for resting CD34(+) progenitor cells, they efficiently block CXCR-4-mediated entry into cells of cell line tropic strains HIV type 1 (HIV-1). Here we...
Schistosomiasis japonicum remains a considerable economic and public health concern in China, the Philippines Indonesia. Currently available measures to control unique intermediate host Oncomelania hupensis are frequently associated with severe side effects. Previous studies have demonstrated that linalool-rich extracts from various plants exhibited promising biological activities including cytotoxic, anti-microbial anti-parasitic properties.We identified components of leaf Cinnamomum...
Dendrobium nobile is a traditional Chinese herb with anti-inflammatory, antioxidant, and neuroprotective properties. However, its antiaging effects are unclear. Herein, we studied the aging-related functions mechanism of action alcohol extract (DnAE) in model organism Caenorhabditis elegans. The results indicated that 1 mg/mL DnAE slowed lipofuscin accumulation, decreased levels reactive oxygen species, elevated superoxide dismutase activity, enhanced oxidative heat stress resistance,...
In the north of China, Diospyros plants are vulnerable to low-temperature damage in winter and is considered as a major factor restricting development persimmon industry Northern China. lotus L. featured by high survival potential seedlings, cold tolerance, grafting affinity with D. kaki Thunb. has been frequently used rootstocks for spp. ERF transcriptional factors subfamily AP2/ERF gene family play an important role plant growth stress tolerance. To explore structure function transcription...