A5101629456- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Biosensors and Analytical Detection
- Cancer-related molecular mechanisms research
- Advanced Biosensing Techniques and Applications
- Oral Health Pathology and Treatment
- Extracellular vesicles in disease
- Salivary Gland Tumors Diagnosis and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Microplastics and Plastic Pollution
- Toxic Organic Pollutants Impact
- Circular RNAs in diseases
- Head and Neck Cancer Studies
- Dermatology and Skin Diseases
- Angiogenesis and VEGF in Cancer
- Electrochemical Analysis and Applications
- Immune cells in cancer
- PI3K/AKT/mTOR signaling in cancer
- Dermatologic Treatments and Research
- Sirtuins and Resveratrol in Medicine
- Bioinformatics and Genomic Networks
- Tryptophan and brain disorders
- Effects and risks of endocrine disrupting chemicals
- Chemokine receptors and signaling
- Electrochemical sensors and biosensors
Guangdong Medical College
2014-2024
Zhujiang Hospital
2022-2024
Southern Medical University
2010-2024
Jinan University
2003-2023
Dongguan People’s Hospital
2023
Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality
2021-2022
Jianghan University
2022
Institute for Systems Biology
2016-2020
Sichuan University
2020
Chinese Academy of Medical Sciences & Peking Union Medical College
2020
To observe the effects of resveratrol (Res) on antioxidative function and estrogen level in an Alzheimer's disease (AD) mouse model.First, we examined Res AD mice model. SAMP8 were selected as model, normal-aging SAMR1 used control group. The model randomly divided into three groups: a group, high-dose group (40mg/kg, intraperitoneal (ip)), low-dose (20mg/kg, ip). After receiving medication for 15 days, subjected to water maze test assess their spatial discrimination. spectrophotometric...
We report a simple, fast, and sensitive approach for visual detection of single-nucleotide polymorphism (SNP) based on hairpin oligonucleotide-functionalized gold nanoparticle (HO-Au-NP) lateral flow strip biosensor (LFSB). The results presented here expand prior work ( Mao , X. Xu H. Zeng Q. L. Liu G. Chem. Commun. 2009 3065-3067 .) by providing new to prepare HO-Au-NP conjugates with deoxyadenosine triphosphate (dATP) blocker, which shortens the preparation time from 50 8 h lowers limit...
Abstract Toxoplasma gondii , the most common parasitic infection of human brain and eye, persists across lifetimes, can progressively damage sight, is currently incurable. New, curative medicines are needed urgently. Herein, we develop novel models to facilitate drug development: EGS strain T. forms cysts in vitro that induce oocysts cats, gold standard criterion for cysts. These highly express cytochrome b . Using these models, envisioned, then created, 4-(1 H )-quinolone scaffolds target...
To recognize new pollution caused by synthetic antioxidants in the environment, a wide range of 18 emerging hindered phenol (HPAs) and 6 sulfur (SAs) were investigated, for first time, through dedicated target screening representative e-waste recycling indoor work environments. All HPAs SAs detected 45 dust samples collected from different categories workshops. Of 24 antioxidants, 22 reported 9 newly identified environment. Pentaerythritol tetrakis[3-(3,5-di-tert-butyl-4-hydroxyphenyl)]...
Triazine UV filters are an important class of filters, but knowledge on their environmental occurrence and human exposure remains largely unknown. In this study, we performed a targeted analysis 17 emerging triazine in indoor dust air from South China based newly developed LC–MS/MS method. A total 12 the were first positively detected samples. Ethylhexyl triazone (EHT) bis-ethylhexyloxyphenol methoxyphenyl (BEMT) identified as most abundant compounds. The median concentrations reached 3860...
Psychological stress is one of the most important factors that trigger emotional disorders, such as depression and anxiety. Emerging evidence suggests neuroinflammation exacerbated by bidirectional communication between peripheral immune system central nervous facilitates abnormal psychiatric symptoms. This study aimed to investigate hippocampal migration bone marrow (BM)-derived monocytes its role in regulating depressive-like behaviors using chronic psychological (CPS) mouse model. More...
In this work, we present a simple and fast approach for simultaneous detection of nucleic acid protein using gold nanoparticles (GNPs) lateral flow device (LFD). Sandwich-type immunoreactions DNA hybridizations were performed simultaneously on the LFD by DNA- antibody-functionalized GNPs. The captured GNPs, due to hybridization immunoreaction events LFD, produced characteristic red bands that could be used qualitative detections and/or protein. proof principle was demonstrated 60-mer rabbit...