Chuanbiao Wen

ORCID: 0000-0003-2279-932X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Traditional Chinese Medicine Studies
  • Computational Drug Discovery Methods
  • Traditional Chinese Medicine Analysis
  • Metabolomics and Mass Spectrometry Studies
  • Biomedical Text Mining and Ontologies
  • Acupuncture Treatment Research Studies
  • Advanced Chemical Sensor Technologies
  • Plant-based Medicinal Research
  • Machine Learning in Healthcare
  • Cancer-related molecular mechanisms research
  • Artificial Intelligence in Healthcare
  • Bioinformatics and Genomic Networks
  • Pharmacovigilance and Adverse Drug Reactions
  • Image Retrieval and Classification Techniques
  • Pharmacological Effects of Natural Compounds
  • Ginseng Biological Effects and Applications
  • ECG Monitoring and Analysis
  • Face and Expression Recognition
  • Complex Network Analysis Techniques
  • Diabetes Management and Research
  • Psychosomatic Disorders and Their Treatments
  • Face recognition and analysis
  • Occupational and environmental lung diseases
  • Phonocardiography and Auscultation Techniques
  • Ferroptosis and cancer prognosis

Chengdu University of Traditional Chinese Medicine
2017-2025

Weatherford College
2023

Deleted Institution
2023

Sichuan Academy of Traditional Chinese Medicine
2023

Hefei Institute of Technology Innovation
2023

National Natural Science Foundation of China
2023

The traditional Chinese Medicine (TCM) herbal formula Lian Hua Qing Wen (LHQW) improves the results of COVID-19 treatment. Three very recent studies analyzed with network pharmacology some working mechanisms LHQW. However, we used more techniques and also included Angiotensin converting enzyme 2 (ACE2) (a SARS-CoV receptor, possibly viral entry point in alveolar lung cells) immune system, as cytokine storm is essential late phase. Extensive detailed Network Pharmacology analysis LHQW-...

10.1016/j.phymed.2020.153336 article EN cc-by-nc-nd Phytomedicine 2020-09-06

Resembling the role of disease diagnosis in Western medicine, pathogenesis (also called Bing Ji) is one utmost important tasks traditional Chinese medicine (TCM). In TCM theory, a complex system composed group interrelated factors, which highly consistent with character systems science (SS). this paper, we introduce heuristic definition network (PN) to represent form directed graph. Accordingly, computational method diagnosis, differentiation (ND), proposed by integrating holism principle...

10.1016/j.artmed.2021.102134 article EN cc-by-nc-nd Artificial Intelligence in Medicine 2021-07-03

As a subclass of the biopharmaceutical classification system (BCS) class II, basic drugs (BCS IIB) exhibit pH-dependent solubility and tend to generate supersaturation in gastrointestinal tract, leading less qualified vitro-in vivo correlation (IVIVC). This study aims develop physiologically based multi-cup dissolution approach improve evaluation for higher quality IVIVC preliminarily explores molecular mechanism precipitation ketoconazole affected by Polyvinylpyrrolidone-vinyl acetate...

10.3390/molecules28196962 article EN cc-by Molecules 2023-10-07

Nowadays, intelligent medicine is gaining widespread attention, and great progress has been made in Western with the help of artificial intelligence to assist decision making. Compared medicine, traditional Chinese (TCM) involves selecting specific treatment method, prescription, medication based on dialectical results each patient's symptoms. For this reason, development a TCM-assisted decision-making system lagged. Treatment syndrome differentiation core TCM treatment; doctors can...

10.2196/29290 article EN cc-by JMIR Medical Informatics 2022-02-13

Temperature can reflect vital activities, and researchers have attempted to guide Chinese medicine diagnosis treatment by observing acupoint temperature changes. Integrating a sensor at the needle tip enables in situ measurement. However, needles for monitoring designed previous studies were fabricated manually soldering thermistor beads metal wires, making mass production difficult. In this work, using MEMS manufacturing technology, flexible that be integrated is proposed mass-produced on...

10.3390/mi15070924 article EN cc-by Micromachines 2024-07-19

Traditional Chinese medicine (TCM) is effective in preventing and treating all manner of diseases, which has been incorporated into the latest global medical outline (Ver.2019) by World Health Organization (WHO). As one most important characteristics TCM, syndrome differentiation (SD) provides curative effect assurance. SD a high-dimensional complex function with symptoms/signs as input type output. Artificial neural network (ANN) an all-purpose data-driven solution to fit function, making...

10.1109/access.2019.2921318 article EN cc-by-nc-nd IEEE Access 2019-01-01

As an effective and novel knowledge management technology, graph can provide a new way for the inheritance development of traditional Chinese medicine (TCM). However, construction TCM is still mainly based on structured data at present. With accumulation literatures electronic medical records, large amount stored in unstructured texts which urgently needs to be extracted learning. In this study, we extract core concepts build ontology layer by analyzing process diagnosis treatment. Then use...

10.1109/icbk50248.2020.00084 article EN 2020-08-01

Adverse drug-drug interaction (ADDI) is referred to as a situation where the unpleasant or adverse effects caused by co-administration of two drugs, which becomes significant problem for public health. With increasing availability healthcare data, many methods are proposed ADDI prediction. However, these usually work in "nondiscriminatory" manner, i.e., they treat each feature without discrimination and equally incorporate all features into predictive models. In practice, only few...

10.1109/tkde.2020.2978055 article EN IEEE Transactions on Knowledge and Data Engineering 2020-01-01

To explore the influencing factors of Yang deficiency constitution in traditional Chinese medicine (TCM) from perspective mathematics with use calculation formulas, so as to protect patients getting diseases caused by and provide suggestions for TCM disease prevention. Based on classification determination criteria implemented China Association Medicine, data 24 solar terms May 5, 2020 (Start Summer) April 20, 2021 (Grain Rain) identification were collected mobile system. The grey...

10.1016/j.dcmed.2023.07.005 article EN cc-by-nc-nd Digital Chinese Medicine 2023-06-01

Fermentation is one of the most traditionally utilized methods to process raw materials traditional Chinese medicine (TCM). Bile Arisaema (BA) produced by fermentation roots heterophyllum with bile. time and bile species are key factors in producing BA. The study was aimed develop a new rapid method for identification different times polysaccharide content (PC), protease activity (PA), amylase (AC) BA were determined. changes PC, PA, AC significant indicators evaluation times. On basis odor...

10.1021/acs.analchem.7b05189 article EN Analytical Chemistry 2018-02-03

According to Traditional Chinese Medicine (TCM), Aconiti Radix Cocta (AC) is clinically employed expel wind, remove dampness, and relieve pain. We evaluated the antirheumatoid arthritis (RA) activities underlying mechanisms of AC. The chemical constituents AC were analyzed by high-performance liquid chromatography (HPLC) using three reference compounds (benzoylaconitine, benzoylmesaconine, benzoylhypacoitine). anti-RA effects in adjuvant-induced (AIA) rats hind paw volume histopathological...

10.1155/2021/5523870 article EN Evidence-based Complementary and Alternative Medicine 2021-09-07

Objective Due to the complexity of face images, tongue segmentation is susceptible interference from uneven texture, lips and face, resulting in traditional methods failing segment accurately. To address this problem, RAFF-Net, an automatic region network based on residual attention multiscale feature fusion, was proposed. It aims improve accuracy achieve end-to-end automated segmentation. Methods Based UNet backbone network, different numbers ResBlocks combined with Squeeze-and-Excitation...

10.1177/20552076221136362 article EN cc-by-nc-nd Digital Health 2022-01-01
Coming Soon ...