Abstract Constructing three‐dimensional (3D) structural characteristics on two‐dimensional (2D) covalent organic frameworks (COFs) is a good approach to effectively improve the permeability and mass transfer rate of materials realize rapid adsorption for guest molecules, while avoiding high cost monomer scarcity in preparing 3D COFs. Herein, we report first time series colyliform crystalline 2D COFs with quasi‐three‐dimensional (Q‐3D) topologies, consisting unique “stereoscopic” triangular...

A multifunctional fluorescent sensor based on a cyclen-appended BINOL derivative (R-1) was synthesized and characterized. It can display on–off-type fluorescence change with high selectivity toward Cu(II) among 19 metal ions in 100% aqueous solution. Furthermore, the situ generated R-1–Cu(II) ensemble could recover quenched upon addition of sulfide anion resulting off–on-type sensing detection limit micromolar range same medium. No interference observed from other biothiols anions, including...

Significant progress has been accomplished in directed C–H functionalization through the use of earth-abundant and inexpensive first-row transition metals.

A coumarin TCF-based water-soluble near-infrared fluorescent probe was presented, which could be used for the rapid, colorimetric and ratiometric detection of SO2 derivatives with a limit 0.27 nM. Moreover, this successfully image analyte in living cells.

Phototheranostics have emerged and flourished as a promising pattern for cancer theranostics owing to their precise photoinduced diagnosis therapeutic meet the demands of precision medicine. The information effect are directly determined by fluorescence imaging ability photothermal conversion efficiency (PCE) phototheranostic agents. Hence, how balance competitive radiative nonradiative processes agents is key factor evaluate effect. Herein, molecules named ICRs with high photostaibility...

Amidation of a variety hydrocarbons with PhINTs catalyzed by ruthenium and manganese meso-tetrakis(pentafluorophenyl)porphyrins 1 2 afforded N-substituted amides in up to 92% yields good excellent substrate conversions. By employing catalyst 2, exceptionally high turnovers (up 2600) were achieved, the amidations can be effected directly using PhI(OAc)2/NH2R as amidating reagents; case R = COCF3 direct amination was realized 90% yield.

It was first observed that PPL, lipase from porcine pancreas, and several other lipases have a promiscuous ability to catalyse asymmetric aldol reactions between acetones aldehydes in the presence of water.

An optically active BINOL-terpyridine based Cu(II) complex (R)-2 was prepared. Sonication of in CHCl(3) led to the formation a stable gel. The interaction this gel with chiral amino alcohols studied. It found that (S)-phenylglycinol (0.10 equiv) could break network (3.75% w/v, g/mL) cause collapsing but (R)-phenylglycinol not. Similar enantioselective also observed (R)- and (S)-1-amino-2-propanol. This study demonstrates molecular gels are potentially useful for visual discrimination....

Chiral metalloporphyrins [Mn(Por*)(OH)(MeOH)] (1) and [Ru(Por*)(CO)(EtOH)] (2) catalyze asymmetric aziridination of aromatic alkenes amidation benzylic hydrocarbons to give moderate enantiomeric excesses. The mass balance in these nitrogen-atom-transfer processes has been examined. With PhI=NTs as the nitrogen source, styrenes, trans-stilbene, 2-vinylnaphthalene, indene, 2,2-dimethylchromene catalyzed by complex 1 or 2 resulted up 99 % substrate conversions 94 aziridine selectivities,...

A novel lipase-catalysed direct Mannich reaction has been developed under aqueous conditions in a “one-pot” strategy. Interestingly, these promiscuous reactions can be greatly promoted by water and generally require aromatic aldehydes.

A ratiometric fluorescent probe () for ClO(-) based on the conjugate of coumarin-rhodamine was presented, which could sense with fast response (within 5 s), high sensitivity and excellent selectivity. More importantly, is first mitochondria-targeted to image exogenous endogenous ClO(-).

Abstract An efficient metal‐free oxidative esterification of benzyl CH bonds was developed. Using tetrabutylammonium iodide as catalyst and tert ‐butyl hydroperoxide co‐oxidant, benzylic substrates could react smoothly with various carboxylic acids to give the esters good excellent yields. The method also suitable for O ‐protection N ‐Boc amino acids. reaction mechanism primarily investigated a radical process proposed.

Two probes that exhibited high sensitivity and excellent selectivity toward ClO⁻among ROS with a rapid response time were presented, which could selectively detect ClO⁻in the mitochondria of cells.

A novel imidazolium-functionalized BINOL fluorescent receptor R-1 was developed as a multifunctional for both chromogenic and chiral anion recognition. The different responses color changes of could be applied to the detection fluoride acetate ions by naked eye. Furthermore, recognition two enantiomers α-amino carboxylates also studied, displayed remarkable binding ability t-Boc alanine with an interesting enantioselectivity (KL/KD = 4.5).

The viscosity of lysosome is reported to be a key indicator lysosomal functionality. However, the existing mechanical methods measurement can hardly applied at cellular or subcellular level. Herein, BODIPY-based two-photon fluorescent probe was presented for monitoring with high spatial and temporal resolution. By installing two morpholine moieties fluorophore as target rotational groups, TICT effect between rings main scaffold endowed excellent sensitivity. Moreover, Lyso-B succeeded in...

A novel mitochondria-targeted ratiometric fluorescent probe for SO₂derivatives was presented, which could selectively respond to HSO₃⁻over other thiol compounds in living cells.

A real-time colorimetric and ratiometric fluorescent probe based on modulating the intramolecular charge transfer (ICT) of coumarin platform for selective detection sulfite is presented. This reaction utilized Michael addition to dicyano-vinyl group with limit 5.8 × 10−5 M. The displayed a high selectivity over other anions reactive sulfur especially biothiols including cysteine (Cys), homocysteine (Hcy) glutathione (GSH), about 100 nm blue shift more than 230 times intensity ratios change...

A reaction-based colorimetric and ratiometric fluorescent probe based on an ICT-strategy for selective detection of H2S that exploited the H2S-mediated reduction nitrocompound to amines was explored. And it displayed high selectivity over other relevant reactive sulfur, oxygen, nitrogen species anions with more than 120 nm blue shift change emission intensity ratio inducted by 4750.

A new iron-catalyzed, direct C-H amination of azoles at C2 has been developed by using formamides or amines as nitrogen sources. Imidazole is the only additive in catalyst system and oxygen air employed during transformation process.