A5105819380- Vascular Anomalies and Treatments
- Tracheal and airway disorders
- Advanced biosensing and bioanalysis techniques
- Organometallic Complex Synthesis and Catalysis
- Epigenetics and DNA Methylation
- Toxic Organic Pollutants Impact
- Nematode management and characterization studies
- DNA and Nucleic Acid Chemistry
- Ginseng Biological Effects and Applications
- Nanocluster Synthesis and Applications
- Phytochemistry and Biological Activities
- Cystic Fibrosis Research Advances
- Forest, Soil, and Plant Ecology in China
- Mitochondrial Function and Pathology
- Evaluation Methods in Various Fields
- Sepsis Diagnosis and Treatment
- Light effects on plants
- Plant and Fungal Species Descriptions
- Obesity and Health Practices
- Alzheimer's disease research and treatments
- Bariatric Surgery and Outcomes
- Phytochemical compounds biological activities
- Plant Parasitism and Resistance
- Traumatic Brain Injury and Neurovascular Disturbances
- Bioinformatics and Genomic Networks
Shanghai Pulmonary Hospital
2020-2024
Sun Yat-sen Memorial Hospital
2024
Sun Yat-sen University
2024
Shanxi Normal University
2024
Tongji University
2020-2024
Affiliated Hospital of Hebei University
2023
South China Agricultural University
2009-2022
Hebei General Hospital
2022
Sichuan University
2017-2021
Shandong University of Finance and Economics
2021
The viscosity of lysosome is reported to be a key indicator lysosomal functionality. However, the existing mechanical methods measurement can hardly applied at cellular or subcellular level. Herein, BODIPY-based two-photon fluorescent probe was presented for monitoring with high spatial and temporal resolution. By installing two morpholine moieties fluorophore as target rotational groups, TICT effect between rings main scaffold endowed excellent sensitivity. Moreover, Lyso-B succeeded in...
Abstract Background With the increasing stress from oil price and environmental pollution, aroused attention has been paid to microbial production of chemicals renewable sources. The C12/14 C16/18 alcohols are important feedstocks for surfactants detergents, which widely used in most respected consumer cleaning products personal care worldwide. Though bioproduction fatty carried out engineered E. coli , several key problems have not solved earlier studies, such as quite low alcohol, lack...
The assembly of a new family [(eta5-C5Me5)MoS3Cu3]-supported supramolecular compounds from preformed cluster [PPh4][(eta5-C5Me5)MoS3(CuNCS)3].DMF (1.DMF) with four multitopic ligands different symmetries is described. Reactions 1 1,2-bis(4-pyridyl)ethane (bpe) (Cs symmetry) or 1,4-pyrazine (1,4-pyz) (D2h in aniline gave rise to two polymeric clusters {[{(eta5-C5Me5)MoS3Cu3}2(NCS)3(mu-NCS)(bpe)3].3aniline}n (2) and [(eta5-C5Me5)MoS3Cu3(1,4-pyz)(mu-NCS)2]n (3). On the other hand, solid-state...
The construction of a new set [(η5-C5Me5)MoS3Cu3]-based supramolecular compounds with different one-dimensional (1D) arrays from two preformed clusters [PPh4][(η5-C5Me5)MoS3(CuX)3] (X = Br (1a), NCS (1b)) 1,2-bis(4-pyridyl)ethane (bpe) and 1,3-bis(4-pyridyl)propane (bpp) is presented. Reactions 1a bpe in molar ratios afforded {[{(η5-C5Me5)MoS3Cu3}2(μ-bpe)3.5Br4]·MeCN}n (2), {[{(η5-C5Me5)MoS3Cu3}2(μ-bpe)3Br4]·Sol}n (3a: Sol DMSO·3MeCN; 3b: 2aniline·3MeCN),...
The chemically selective detection of natural nucleobase modifications has been regarded as the key step in understanding their important roles epigenetics. Herein, for first time, we introduce a Wittig reaction into design reaction-based fluorescent probes ratiometrically detecting 5fU, selectively labelling 5fU-modified DNA and imaging intracellular 5fU produced by γ-irradiation.
Abstract Background Nearly half of bronchiectasis patients receiving bronchial artery embolization (BAE) still have recurrent hemoptysis, which may be life-threatening. Worse still, the underlying risk factors recurrence remain unknown. Methods A retrospective cohort was conducted with idiopathic who received BAE from 2015 to 2019 at eight centers. Patients were followed up for least 24 months post BAE. Based on outcomes hemoptysis and severe a Cox regression model used identify recurrence....
The present study evaluated the potential of endogenous enzymes and probiotics in transforming bioactive metabolites to reduce purgative effect improve functional activity Cassiae Semen verified revealed biotransformation enzymes. Although probiotics, especially Lactobacillus rhamnosus, exerted transformation effect, proved be more effective components Semen. After by for 12 h, levels six anthraquinones increased at least 2.98-fold, free anthraquinones, total phenolics, antioxidant also...
The pathogenic fungus Colletotrichum musae infects developing green bananas ( Musa spp. AAA group), but remains latent until the fruit ripens. aim of this research was to determine whether appearance disease symptoms is regulated by chitinase gene expression following treatment with benzothiadiazole (BTH) and methyl jasmonate (MeJA), physical (heat) chemical (H 2 O Ca 2+ -related) treatments. In inoculated C. , BTH MeJA lowered severity stimulated higher compared untreated controls during...
In view of the important epigenetic functions 5-formylcytosine (5fC), development quantitative detection methods for 5fC is a long-standing issue. this regard, how to distinguish from 5-formyluracil achieve higher accuracy particularly difficult because latter one more reactive. Herein, we reported phosphorus ylide, YC–CN, and introduced triple domino reaction fluorescently switch on with excellent selectivity, which also enable us quantify mutations induced by γ-irradiation. This...
Toona ciliata and sinensis belong to the genus of Meliaceae family are important timber species in China. T. is an endangered at level II due overcutting a low rate natural regeneration. was cultivated as economic nutritious tree for more than 2000 years. The two differ flower leaf morphological traits, reproductive systems, range size distribution. To reveal potential molecular basis these divergences, we examined similarities differences their whole genome sequences. Results indicate that...
Hepatocarcinoma is one of the most lethal malignancy haunting Chinese population, which partially due to difficulties in diagnosis at an early stage. The search for a biomarker that could signify presence and progress hepatocarcinoma never ended. MicroRNAs are 22-nt RNAs bind 3' UTR target mRNAs, mediating degradation mRNAs or inhibiting translation. Although much has been investigated, role miR-124 remained elusive. We first detected aberrant expression level HCC tissues 112 patients. By...
In this study, small molecular (≤3 kDa) Coix glutelin hydrolysate (CGH) was obtained by the method of enzymatic hydrolysis and then immunomodulatory activity evaluated in vitro vivo. Stimulation index mice splenocytes increased a dose-dependent manner after treated with 3.125–25 μg/mL CGH. Acid phosphatase peritoneal macrophages significantly improved stimulated CGH at some concentration. The secretion NO from Raw264.7 concentration-dependent also inhibited lipopolysaccharide-induced cell...
Abstract Background Pulmonary arteriovenous malformations (PAVMs) are rare but cause various manifestations. Although the diameter of feeding arteries has been linked to treatment decisions, relationships among characteristics PAVMs, clinical symptoms, and effect remain unclear. The present study was performed investigate how collective PAVMs relate symptoms provide proper recommendations for patients with PAVMs. Methods We retrospectively analysed 838,447 patients’ radiographic data medical...
To investigate the predictive value of neuron-specific enolase (NSE) on intensive care unit (ICU) mortality in patients with septic shock. Seventy-five shock hospitalized emergency (EICU) Hebei General Hospital from March 2020 to September 2021 were included, and patients’ baseline characteristics laboratory findings collected. NSE levels first fourth days after admission retrieved. NSE% [(NSEday1 – NSEday4)/NSEday1 × 100%] δNSE (NSEday1 NSEday4) calculated. The outcome indicator was ICU...
A novel pyrene-based fluorescent probe (3-methyl-2-(pyren-1-yl)benzo[<italic>d</italic>]thiazol-3-ium iodide) (<bold>PBT</bold>) was found to be a fast-responsive and highly selective towards G-quadruplexes. <bold>PBT</bold> exhibited an opposite variation tendency on binding with G-quadruplexes ds-DNAs.
Remote sensing monitoring of black-odor water is an important method for understanding the current status urban quality, and comprehensively evaluating effect environment treatment. A total 171 samples were collected in Nanjing, Changzhou, Wuxi, Yangzhou cities quality parameters optical measured simultaneously. Based on analysis color characteristics non-black-odor (denoted as general water), a decision tree was constructed to identify severe, mild water, green yellow water. The results...
In order to understand the effects of lucerne cropping rotation on bacterial community loess soil, a long-term field experiment was conducted in rain-fed agricultural area Loess Plateau. The systems included continuous (Medicago sativa, LC), removed and rotated with spring wheat (Triticum aestivum, LFW), corn (Zea mays, LFC), potato (Solanum tuberosum, LP), millet (Panicum miliaceum, LM). Based 16S rRNA high-throughput sequencing technology, we investigated soil structure diversity different...