A5101563029- Meat and Animal Product Quality
- Selenium in Biological Systems
- Animal Nutrition and Physiology
- Antioxidant Activity and Oxidative Stress
- Pharmacological Effects and Assays
- Trace Elements in Health
- Metabolomics and Mass Spectrometry Studies
- Heavy Metal Exposure and Toxicity
- Veterinary Pharmacology and Anesthesia
- Mercury impact and mitigation studies
- Pesticide Residue Analysis and Safety
- Advanced Chemical Sensor Technologies
- Gut microbiota and health
- Fatty Acid Research and Health
- Sulfur Compounds in Biology
- Animal Behavior and Welfare Studies
- Pharmacological Effects of Natural Compounds
- Identification and Quantification in Food
- Biochemical Analysis and Sensing Techniques
- Aquaculture Nutrition and Growth
- Ginseng Biological Effects and Applications
- Research in Cotton Cultivation
- Medicinal Plant Pharmacodynamics Research
- Liver Disease Diagnosis and Treatment
- Isotope Analysis in Ecology
Chinese Academy of Agricultural Sciences
2016-2025
Institute of Animal Sciences
2019-2025
Third Xiangya Hospital
2025
Central South University
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Ministry of Agriculture and Rural Affairs
2018-2023
Stanford University
2022
National Animal Husbandry Service
2015
Selenium (Se) intake disequilibrium is associated with many human diseases (e.g., Keshan disease and type 2 diabetes). To understand the mechanism of Se deficiency-induced hepatic pathogenesis, a pure line pig model was established by feeding diet either 0.07 mg/kg or 0.3 for 16 weeks. The metabolome, lipidome, global proteome, whole transcriptome were analyzed. deficiency causes redox imbalance via regulation selenoproteins at both mRNA protein level, blocks glutathione anti-oxidant system...
Growth-promoting antibiotics have been banned by law in the livestock and poultry breeding industry many countries. Various alternatives to investigated for using livestock. Epimedium (EM) is an herb rich flavonoids that has beneficial effects on animals. Therefore, this study was planned explore potential of EM as a new alternative antibiotic product animal feed.A total 720 1-day-old male broilers (Arbor Acres Plus) were randomly divided into six groups fed basal diet (normal control; NC),...
Melanin as a natural pigment widely exists in animals, plants, fungi and bacteria. In vivo vitro tests have proven that melanin has variety of health-promoting effects, such antioxidant immunomodulatory activities, hypoglycemic hypolipidemic effect, liver gastrointestinal tract protection effect. can be extracted from animal plant by-products or produced by microbial fermentation, involving five extraction purification methods, with their own positive negative aspects. added to foods...
Abstract Selenium (Se) is closely associated with kidney disease, and renal injury often occurs together hyposelenemia. This study was designed to reveal the mechanism underlying induced by Se deficiency in pigs. Twenty-four castrated male Yorkshire pigs were divided into two groups fed either a Se-deficient diet (0.007 mg per kg) or Se-adequate (0.3 kg). Serum samples collected at 16th week of trial, processed, analyzed for serum biochemistry, concentration, index markers, histology,...
Abstract Background The immune system is one aspect of health that affected by dietary selenium (Se) levels and selenoprotein expression. Spleen an important organ the body, which directly involved in cellular immunity. However, there are limited reports on Se spleen health. Therefore, this study established a Se-deficient pig model to investigate mechanism deficiency-induced splenic pathogenesis. Methods Twenty-four pure line castrated male Yorkshire pigs (45 days old, 12.50 ± 1.32 kg, 12...
We investigated the effects of astaxanthin supplementation on egg quality, antioxidant capacity, and ovarian aging aged laying hens. Six groups 68-wk-old Hy-line brown hens with six replications each, fifteen chickens in each replicate were fed for 12 wk. The control group was a basal diet, positive diet supplemented 100 mg/kg vitamin E, experimental 15 mg/kg, 30 45 or 60 (Ax15, Ax30, Ax45, Ax60, respectively). results showed that accumulated yolks improved yolk color (P < 0.01) Haugh unit...
Sheep breed has a major influence on characteristics of meat quality and intramuscular fat (IMF), however, studies into the relationship between sheep traits rarely consider large variation in IMF within breed. In this study, groups 176 Hu 76 Tan male were established, weaned at 56 days old, with similar weights, representative samples selected based distribution each population, to investigate variations quality, volatile compound profiles breeds. Significant differences observed drip loss,...
Taihe silky chicken (TSC) has been consumed as a specialty food in China for over 2200 years. In this study, LC/MS-based lipidomics and GC/MS-based volatilomics were used to compare lipids volatile compounds of Cobb (CC) TSC investigate the differences meat quality between them. showed higher intramuscular fat content, linoleic acid (C18:2), arachidonic (C20:4), dococsahexaenoic (C22:6, DHA) (p < 0.05). Lipidomic analysis revealed significant CC at class molecular levels. We found that 106...
Silkie chicken, an important chicken breed with high medicinal and nutritional value, has a long history of being used as dietary supplement in China. However, the compounds health-promoting effects chickens remain unclear. In present study, we conducted comprehensive analysis metabolic lipidomic profiles to identify characteristic bioactive chickens, using common control. The results showed that levels 13 metabolites including estradiol, four lipid subclasses cardiolipin (CL), eight...