A5075054322- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Eosinophilic Esophagitis
- Microscopic Colitis
- Advanced Glycation End Products research
- Long-Term Effects of COVID-19
- Alcohol Consumption and Health Effects
- Intraperitoneal and Appendiceal Malignancies
- Maternal and fetal healthcare
- Forensic Toxicology and Drug Analysis
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Infectious Aortic and Vascular Conditions
- Viral Infections and Vectors
- Pediatric Hepatobiliary Diseases and Treatments
- Neurological and metabolic disorders
- MicroRNA in disease regulation
- Platelet Disorders and Treatments
- Berberine and alkaloids research
- Sphingolipid Metabolism and Signaling
- Organ Transplantation Techniques and Outcomes
- Schizophrenia research and treatment
- Endoplasmic Reticulum Stress and Disease
University of North Dakota
2023-2025
Mayo Clinic in Arizona
2021-2025
North Dakota State University
2024
Mayo Clinic
2021-2023
WinnMed
2021-2023
Lady Hardinge Medical College
2021
Griffin Hospital
2021
Memorial Hospital
2021
Deccan College of Medical Sciences
2021
Allama Iqbal Medical College
2021
Intrahepatic macrophages in nonalcoholic steatohepatitis (NASH) are heterogenous and include proinflammatory recruited monocyte derived macrophages. The receptor for advanced glycation end products (RAGE) is expressed on can be activated by damage associated molecular patterns (DAMPs) upregulated NASH, yet the role of macrophage-specific RAGE signaling NASH unclear. Therefore, we hypothesized that expressing mediate liver inflammation NASH. Compared to healthy controls, expression was...
Immune cell-driven inflammation is a key mediator of metabolic dysfunction-associated steatohepatitis (MASH) progression. We have previously demonstrated that pharmacological sphingosine 1-phosphate (S1P) receptor modulation ameliorates MASH and associated with attenuated accumulation intrahepatic macrophage T-cell subsets. Although S1P receptors are expressed on several immune cell types, given the prominent role monocyte-derived recruited macrophages in sterile MASH, we hypothesized...
Department of Internal Medicine, University North Dakota, Fargo, USA Abbreviations: HRV, high-risk varices; PSVD, porto-sinusoidal vascular disorder; SSM, spleen stiffness measurement. Correspondence Guneet Sidhu, Fargo 58104, ND, USA. Email: [email protected]
Gastroduodenal artery (GDA) pseudoaneurysm is a rare complication of gastric and pancreatic surgery. The presentation often severe gastrointestinal (GI) bleeding with up to 90% mortality rate. Proper identification past gastrectomy based on history or endoscopic appearance essential for timely embolization surgery, given that management fails. Here, we present 65-year-old man who has ulcer-related surgery without clear documentation hypertension presented hematemesis, black stools, syncope....
Neurologic complications are a hallmark of infective endocarditis (IE). IE leading to intracranial abscess has an unfavorable prognosis. A 17-year-old boy with past medical history aortic valve replacement presented fever and seizure. On examination, he had tachycardia, systolic murmur, slurred speech, meningeal signs, right homonymous hemianopia. His laboratory analysis revealed elevated erythrocyte sedimentation rate C-reactive protein. The brain's magnetic resonance imaging multiple...
Alcohol-associated liver disease (ALD) has been recognized as the most common cause of advanced worldwide, though mechanisms pathogenesis remain incompletely understood. The X-linked inhibitor apoptosis (XIAP) protein was originally described an anti-apoptotic that directly binds and inhibits caspases-3, 7, 9. Here, we investigated function XIAP in hepatocytes vitro using gain loss-of-function approaches. We noted XIAP-dependent increase caspase activation well increased inflammatory markers...
Department of Internal Medicine, University North Dakota, Fargo, USA Correspondence Guneet S. Sidhu, ND 58104, USA. Email: [email protected]
Opiate withdrawal-induced severe exacerbation of psychosis after the sudden withdrawal an opiate is a known yet uncommon clinical manifestation. We present case in 25-year-old married male patient without any prior psychiatric history illness, family history, or past hospitalization records. The presented with psychotic symptoms such as irritability, delusions parasitosis, and auditory visual hallucinations at time hospitalization. Symptoms were fluctuating course not constant throughout...
Singh, Romil; Rathore, Sawai; Khan, Hira; Karale, Smruti; Bhurwal, Abhishek; Tekin, Aysun; Jain, Nirpeksh; Mehra, Ishita; Anand, Sohini; Allam, Sanjana; Sidhu, Guneet; Panagopoulos, Anastasios; Pattan, Vishwanath; Kashyap, Rahul; Bansal, Vikas Author Information
Introduction: Heyde syndrome is described as a triad of gastrointestinal atrial venous malformations, aortic stenosis and acquired von Willebrand's deficiency. Case Description/Methods: An 80-year-old man presented to the ER with increasing weakness fatigue for 6 months. Hemoglobin on admission was 4.6 g/dL. His prior medical history included multiple hospital admissions lower GI bleeding. No apparent alcohol intake, smoking or any illicit drug use. On initial presentation he appeared...
Introduction: Hereditary tyrosinemia type 1 (HT1), is the most severe disorder of tyrosine metabolism. HT1 occurs in 12,000 to 100,000 individuals Northern European descent. Liver transplantation an effective treatment. Case Description/Methods: A 31-year-old man with biopsy confirmed renal glomerulosclerosis on peritoneal dialysis was evaluated for advanced fibrosis/cirrhosis his hepatic graft. At year age, he diagnosed HTI and underwent cadaveric liver transplant 1992 at University...