A5032982154- Hypothalamic control of reproductive hormones
- Ovarian function and disorders
- Regulation of Appetite and Obesity
- Dietary Effects on Health
- Adipose Tissue and Metabolism
- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Hormonal and reproductive studies
- Cancer, Lipids, and Metabolism
- Chronic Disease Management Strategies
- Cancer Research and Treatments
- Thermoregulation and physiological responses
- Autophagy in Disease and Therapy
- Cancer, Stress, Anesthesia, and Immune Response
- Health and Lifestyle Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Plant Reproductive Biology
- Neuroblastoma Research and Treatments
- Diet, Metabolism, and Disease
- Prostate Cancer Treatment and Research
- Cardiovascular Disease and Adiposity
- Sports and Physical Education Research
- Growth Hormone and Insulin-like Growth Factors
Nanjing Sport Institute
2019-2023
Beijing Sport University
2018-2022
ORCID
2021
81th Hospital of PLA
2011-2012
Zhujiang Hospital
2011
Southern Medical University
2011
Osaka University
2006
Air Force Medical University
2006
Abstract Purpose To find the expression of KISS-1 and G protein-coupled receptor 54 in rats testis from PND 21st to 56th. Method 128 three-week-old weaned underwent high-fat diet exercise (60–70% VO 2max , 1 h/day, 5 days/week) intervention were randomly divided into group C, CE, HC, or HE. Sample time points set on 21st, 35th, 43rd, The testicular testosterone mRNA content, protein content GPR54 tissue detected by ELISA, RT-qPCR, Western blotting. Result (1) increased gradually during...
Abstract Background Kiss-1 neuron, one of the metabolic sensors in hypothalamus, is necessary for puberty initiation. It acts through G protein-coupled receptor, known as GPR54. In this study, mechanism hypothalamic Kiss-1–GPR54 signaling pathway a high-fat diet and exercise was investigated growing male rats. Methods A total 135 3-week-old weaned rats were kept on (HFD) (60–70% $$\dot{\mathrm V}{\mathrm O}_{2\max}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow>...
Background Intermittent energy restriction (IER) and continuous (CER) are increasingly popular dietary approaches used for weight loss overall health. These protocols combined with exercise on other health outcomes could achieve additional effects in a short-term intervention. Objectives To evaluate the of 4-week IER or CER program weight, blood lipids, CRF overweight/obese adults when high-intensity interval training (HIIT). Methods Forty-eight [age: 21.3 ± 2.24 years, body mass index...
Background: Uncoupling protein 2 ( UCP2 ) plays an important role in regulating body weight, energy expenditure and insulin secretion. is upregulated white fat response to feeding, negatively controls also has a function that protects cells from apoptosis oxidative stress, which shows might be senescence‐related gene. Previously, ‐866G/A polymorphism the promoter region been reported alter adipose tissue mRNA expression associated with obesity Caucasians. Methods: In this study, we...
Objective To determine if activation of AMP-activated protein kinase (AMPK) is involved in ropivacaine-induced reactive oxygen species (ROS) production and apoptosis human neuroblastoma cell line SHSY5Y.Methods SH-SY5Y was purchased from center Shanghai life Science Research Institute,Chinese Academy Sciences cultured DMEM/F12 liquid culture medium containing 15 % bovine calf serum at 37 ℃ incubator filled with 5% CO2 . Plasmids pGPU6/GFP/Neo-shRNA AMPKα2 pEGFP-N1-AMPKα2were transfected into...
Kisspeptin, a hypothalamic peptide coded by the KiSS1 gene, is neuromodulator that controls GnRH secretion and now recognized as crucial regulator of onset puberty. PURPOSE: To explore difference roles moderate-intensity treadmill training (MIT) high intensity interval (HIIT) in modulating expression KiSS-1and G-protein coupled receptor (GPR) 54 mRNA diet induced obesity male rats. METHODS: After 8 weeks fat feeding, 24 11-weeks SD rats were randomly assigned to sedentary (FS, n=8), MIT...
Kisspeptin, in addition to reflects its ability inhibit cancer metastasis, which have been implicated the regulation of GnRH secretion with receptor GPR54, play an essential role normal reproduction and pubertal development. PURPOSE: To explore moderate-intensity treadmill training (MIT) modulating hypothalamic expression kiss-1 G protein coupled -GPR54 mRNA relative different time puberty. METHODS: 3 weeks male Sprague-Dawley rats (weight:62.03±3.13) were randomly assigned two experimental...
Objective To observe the effect of high fat diet on hypothalamic expression KiSS-1and G-protein coupled receptor (GPR) 54 mRNA and explore modulatory role moderate-intensity exercise in induced obesity male rats.
 Methods After 8 weeks feeding, 20 11-weeks SD rats were randomly assigned to high-fat sedentary (FS, n=8) (FE, groups, normal also (SS, (SE, groups. During following weeks, continued expose high-fat-diet. SE FE groups did 60%-70%V(•)O2max treadmill training (5 days/week, 1...
PURPOSE: The study aims to investigate the effect of 8 weeks moderate intensity exercise on level autophagy in skeletal muscle obese rats. Based this, further explore effective load for promoting autophagy, and possible mechanism enhanced exercise-trained METHODS: 40 11-week-old male SD rats were selected after adaptive feeding divided into normal control group high-fat group. These groups then subdivided group(control trained group(CT), group(OT)) sedentary groups(control group(CS), obesity...
Hypothalamic Kisspeptin/GPR54 system is the "control switch" for onset of puberty. Obesity induced by high-fat diet and/or physical inactivity a leading cause precocious PURPOSE: To observe effect on hypothalamic expression KiSS-1, G-protein coupled receptor (GPR) 54and GnRH mRNA and explore modulatory role moderate-intensity exercise in high-fat-diet feeding male rars ,which are growth period. METHODS: Male weanling rats (21std) were fed high-fat-die randomly assigned to chow sedentary (CS,...
Kisspeptins, encoded by the Kiss1 gene, is unanimously recognised as essential regulators of regulating gonadotropin secretion. It mainly expressed in arcuate nucleus hypothalamus, and have a direct role energy balance. PURPOSE: To explore high fat diet(HFD) moderate-intensity treadmill training (MIT) modulating hypothalamic expression kiss-1 mRNA relative kisspeptin-immunoreactivity 3 weeks post-weaning rats. METHODS: The SD rats (weight= 58.54±2.69g) after 5 feeding, 30 HFD 8-weeks were...
Abstract Background: Kiss-1 neurons, one of the metabolic sensors in hypothalamic, is necessary for puberty initiating and acts through G protein-coupled receptor, known as GPR54. This study investigated mechanism hypothalamic Kiss-1-GPR54 signaling pathway high-fat diet exercise on growing male rats. Methods: 135 three-week-old weaned rats were underwent (60–70% VO 2max , 1 h/day, 5 days/ week). These mice randomly divided into control group, group. Hypothalamic, testis, serum samples each...